Hotels in Saint Charles

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A spacious lobby with high ceilings, large windows, and a chandelier.

A double door entrance to a hotel with a sign above reading "PROUDFOOT & BIRD".

A spacious lobby with high ceilings, large windows, and a central chandelier. There are multiple seating areas with tables and chairs.

A spacious lobby with a central round table, green seating, and large arched windows.

1. Hotel Fort Des Moines, Curio Collection by Hilton

Downtown Des Moines

$144

$161 total

includes taxes & fees

Oct 4 - Oct 5

A hotel room with a large bed, a nightstand, a wall-mounted TV, and a window with curtains.

An indoor swimming pool with clear windows, white chairs, and a blue and white color scheme.

A gym with treadmills, elliptical machines, and a water dispenser.

A Days Inn & Suites sign, a parking lot, and a building with multiple floors and windows.

2. Days Inn & Suites by Wyndham Des Moines Airport

Greater South Side

$65

$73 total

includes taxes & fees

Nov 1 - Nov 2

A modern hotel room with a large bed, a built-in desk, a vanity with a bathtub, and a large window with curtains.

A reception area with a white counter, a clock, and a digital display.

A hallway with vending machines and a clean, tiled floor.

A restaurant with multiple tables and chairs, a kitchen area, and a stone accent wall.

3. Sonesta Essential Des Moines

Lovington

$68

$79 total

includes taxes & fees

Oct 8 - Oct 9

An indoor pool with slides and a ship-themed play area.

A spacious restaurant with wooden tables and chairs, a stone wall, and a large window overlooking the dining area.

A lobby with a reception desk, a curved seating area, and a decorative palm tree centerpiece.

A bar area with a central counter, multiple bar stools, and a decorative figure on top.

4. Ramada Tropics Resort & Conf Center by Wyndham Des Moines

Urbandale

$71

$80 total

includes taxes & fees

Oct 18 - Oct 19

A spacious, modern interior with a long wooden table and bar stools, a seating area with sofas, and a kitchen area with a countertop and shelving.

A modern conference room with a large wooden table, comfortable seating, and a fireplace.

An indoor swimming pool with clear water, surrounded by lounge chairs and tables.

5. La Quinta Inn & Suites by Wyndham Johnston

Johnston

A building with a sign reading "WILDWOOD LODGE."

A cozy living room with a stone fireplace, a sofa, and a coffee table.

A spacious lobby with a reception desk, seating area, and a view of the outdoors.

A spacious lobby with a central seating area, large windows, and a distinctive antler decoration.

6. Wildwood Lodge

Clive

$104

$116 total

includes taxes & fees

Oct 11 - Oct 12

An indoor swimming pool with a 30 ft depth sign, a reception area, and a 'No Lifeguard' warning sign.

A lobby with striped orange chairs, a green ottoman, and a fireplace.

A spacious dining area with a long table and multiple chairs, large windows, and orange walls.

A lobby with a checkered armchair, a yellow sofa, a glass-top coffee table, and a cabinet with glass doors.

7. Drury Inn & Suites West Des Moines

West Des Moines

$100

$112 total

includes taxes & fees

Nov 1 - Nov 2

An outdoor dining area with a table set for two, featuring a cocktail and candles.

A multi-level hotel lobby with a central atrium, multiple floors, and a variety of seating areas.

A multi-level hotel atrium with balconies, indoor plants, and artwork on the walls.

A multi-level hotel lobby with a central pool, dining area, and a bar.

8. Embassy Suites Hotel Des Moines Downtown

Downtown Des Moines

$130

$146 total

includes taxes & fees

Oct 11 - Oct 12

An outdoor seating area with yellow chairs and a colorful sofa, a fire pit, and a wooden ceiling with hanging lights.

A modern restaurant with a long wooden table and chairs, a counter with a beverage dispenser, and shelves with bowls and glasses.

A hotel with a modern exterior, a covered outdoor seating area, and a traditional building in the background.

A hotel room with a bed, a sofa, a desk, and a television.

9. Home2 Suites by Hilton Des Moines at Drake University

Drake

$105

$117 total

includes taxes & fees

Nov 2 - Nov 3

A luxurious living room with a stone fireplace, a large mirror, and two blue armchairs.

A spacious hotel lobby with high ceilings, ornate chandeliers, and a bar area.

A hotel lobby with a polished marble floor, a grand chandelier, and traditional decor including lion statues.

A hotel facade with a brick exterior, large windows, and a prominent entrance sign.

10. Des Lux Hotel

Downtown Des Moines

$169

$189 total

includes taxes & fees

Oct 4 - Oct 5

An indoor swimming pool with tiled flooring, a wooden ceiling, and a seating area with chairs and umbrellas.

A multi-story brick building with a covered entrance, flagpoles, and a landscaped area with trees.

A spacious living area with a staircase, a fireplace, a wooden desk, and a dining area.

A reception area with a wooden counter, overhead pendant lights, framed pictures on the wall, and a refrigerator stocked with beverages.

11. Country Inn & Suites by Radisson, Des Moines West, IA

Clive

$81

$91 total

includes taxes & fees

Nov 1 - Nov 2

An indoor swimming pool with a waterfall feature, surrounded by Adirondack chairs and a wooden deck.

A wooden interior with a reception desk, a mounted moose head, and a staircase.

A building with a sign reading "The Cottages" and a covered outdoor seating area.

A hotel room with a large bed, a fireplace, a TV, and a jacuzzi.

12. Stoney Creek Hotel Des Moines - Johnston

Johnston

$109

$122 total

includes taxes & fees

Oct 4 - Oct 5

A spacious lobby with a high ceiling, a central seating area with a blue sofa and chairs, a dining area, and a staircase leading to an upper level.

A vending machine area with various snacks and drinks.

A spacious lobby with a curved blue sofa, a round coffee table, and a seating area with chairs. There is a staircase with a railing leading to an upper level.

A multi-story hotel with a prominent entrance, a large glass facade, and a parking lot.

13. Fairfield Inn and Suites by Marriott Des Moines West

West Des Moines

$97

$108 total

includes taxes & fees

Oct 18 - Oct 19

A spacious indoor area with multiple levels, featuring a central open space with tables and chairs, surrounded by balconies and a large, colorful ceiling structure.

A spacious lobby with large windows, a potted plant, and a seating area.

A gym with treadmills, elliptical machines, and free weights.

A multi-level indoor swimming pool with a clear water surface, surrounded by colorful lounge chairs and a stone wall.

14. Holiday Inn Des Moines-Airport/Conf Center by IHG

Greater South Side

$114

$128 total

includes taxes & fees

Oct 26 - Oct 27

A living room with a sofa, a patterned armchair, a coffee table, and a dining area with chairs and a table.

An indoor swimming pool with blue lounge chairs, a red brick border, and a ceiling with recessed lighting.

An outdoor patio area with picnic tables and benches, large windows, and a building with a brick facade in the background.

A reception area with a receptionist, a clock, a desk, a mirror, and a welcome mat.

15. AmericInn by Wyndham Johnston Des Moines

Johnston

$60

$67 total

includes taxes & fees

Oct 8 - Oct 9

An outdoor dining area with tables and chairs, a large umbrella, and a TV screen.

A modern hotel room with a large city view, a sofa, a dining area, and a small table with a decorative item.

A modern hotel with a prominent 'Hilton' sign, large windows, and a covered outdoor area with seating.

A modern restaurant with a large, abstract wall art piece, multiple seating areas, and a staircase leading to an upper level.

16. Hilton Des Moines Downtown

Downtown Des Moines

$136

$157 total

includes taxes & fees

Oct 11 - Oct 12

An outdoor patio with modern seating and a built-in fireplace.

A La Quinta hotel entrance with a modern design, numbered 1390, and a landscaped entrance area.

A modern restaurant with a long counter, multiple seating areas, and a kitchen visible in the background.

An indoor swimming pool with clear glass walls, a lifeguard chair, and a pool ladder.

17. La Quinta Inn & Suites by Wyndham Des Moines West Clive

Clive

$78

$88 total

includes taxes & fees

Nov 1 - Nov 2

A bar area with multiple screens displaying sports and news, a cash register, and bar stools.

A hotel with a pool area, outdoor seating, and a building with multiple floors and windows.

A lobby with a stone wall, a fireplace, a TV, red sofas, and two lamps.

A coffee shop interior with a menu board, a bakery display case, and a counter with a cash register.

18. Lakeside Hotel Casino, a Travelodge by Wyndham

Osceola

$72

$95 total

includes taxes & fees

Oct 4 - Oct 5

A sunroom with a glass ceiling, wicker furniture, and potted plants.

An indoor swimming pool with clear glass walls, white lounge chairs, and a tiled floor.

A spacious lobby with a high ceiling, a seating area with sofas and ottomans, a reception desk, and a staircase to an upper level.

A hotel room with a bed, a blue armchair, a desk, and a nightstand.

19. Baymont by Wyndham Des Moines Airport

Southwestern Hills

$83

$93 total

includes taxes & fees

Oct 25 - Oct 26

A spacious hotel lobby with a blue sofa, a grey armchair, and a flat-screen TV mounted on a textured wall.

A Comfort Inn hotel with a modern facade, multiple floors, and a parking lot with cars.

A hotel lobby with a blue sofa, a beige armchair, a flat-screen TV mounted on a textured wall, a fireplace, and a dining area in the background.

An indoor swimming pool with a blue and white color scheme, a lifeguard station, and seating areas with chairs and tables.

20. Comfort Inn & Suites Event Center

Downtown Des Moines

$93

$104 total

includes taxes & fees

Oct 25 - Oct 26

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Go beyond your typical stay in Saint Charles

Pet friendly

Hot tub

Pool

Family friendly

Top landmarks in Saint Charles

Imes Bridge

7.8/10 (17 reviews)

If you're planning a bit of sightseeing during your trip, head to Imes Bridge— just one of the landmarks located 0.5 mi (0.9 km) from central Saint Charles.

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Learn more about Saint Charles

The region around Saint Charles is home to attractions such as Imes Bridge and John Wayne Birthplace Museum.

See all hotels in Saint Charles

A covered bridge with a sign reading "GUTLER-DONAHUE BRIDGE Built 1870" in a forested area.

Check out reviews of Saint Charles hotels guests love

Hotel Fort Des Moines, Curio Collection by Hilton

10/10 Excellent

"Great location, beautiful hotel, nice rooms."

Motel 6 West Des Moines, IA

8/10 Good

"It was a Motel 6, so expectations weren't high. The room was OK, and it's always nice not to pay extra for a pet. However, the exterior was in pretty bad shape. The sidewalks were cracked an splitting, windows were foggy and dirty."

Days Inn & Suites by Wyndham Des Moines Airport

10/10 Excellent

"The pool was warm, the staff was great, clean room, hot water, breakfast was decent. Great price, great stay."

Drury Inn & Suites West Des Moines

10/10 Excellent

"Great stay. Friendly staff, clean comfortable room. Good breakfast"

Hampton Inn Des Moines-Airport

10/10 Excellent

"Very close to the airport, and a shuttle service. Lovely staff, quiet and clean rooms."

Hyatt Place West Des Moines Jordan Creek

8/10 Good

"Hotel is starting to show a little age"

Des Lux Hotel

10/10 Excellent

"Really unique and comfortable stay. Would highly recommend."

SpringHill Suites Des Moines West

10/10 Excellent

"Very comfortable, clean rooms, excellent breakfast"

Country Inn & Suites by Radisson, Des Moines West, IA

10/10 Excellent

"We had a wedding we were at and needed to check in a little earlier and Jeff the manager"

Frequently asked questions

Can I book a refundable hotel in Saint Charles?

If you're looking for the flexibility to change your plans to Saint Charles, most hotels provide refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Saint Charles be like during my trip?

The warmest months in Saint Charles are usually July and August with an average temp of 72°F. January and February are the chilliest months when the average temp is 29°F. The rainiest months are May and June.

Why should I book my Saint Charles hotel through Hotels.com?

There are plenty of reasons to book your Saint Charles travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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