Hotels in Wyatt

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Check prices for these dates

Tonight
Nov 2 - Nov 3
Tomorrow
Nov 3 - Nov 4
This weekend
Nov 6 - Nov 8
Next weekend
Nov 13 - Nov 15

Where to stay in Wyatt?

A hotel room with a large bed, two bedside lamps, a framed picture of a bridge, and a wooden nightstand with a phone.

1. Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.8 out of 10, Good, (682 reviews)
This Charleston motel offers complimentary WiFi, parking, and on-the-go breakfast daily. Located with convenient interstate access to Cape Girardeau, guests consistently praise the helpful staff. The comfortable accommodations provide a practical base for exploring southeastern Missouri.
The price is $59
$66 total
includes taxes & fees
Dec 1 - Dec 2
Super 8 by Wyndham Charleston/Sikeston East MO
A hotel lobby with a reception desk, seating area, and a large window.

2. Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.4 out of 10, Good, (296 reviews)
Set off I-57 in Cairo, this welcoming hotel provides complimentary full breakfast and self parking. Explore nearby Fort Defiance State Park or take a short drive to Ballard Wildlife Management Area while enjoying free WiFi throughout your stay.
The price is $69
$76 total
includes taxes & fees
Nov 15 - Nov 16
Quality Inn Cairo I-57
A building with a fountain and flower beds in front.

3. The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, Good, (443 reviews)
The price is $66
$74 total
includes taxes & fees
Nov 4 - Nov 5
The Riverstone Hotel Charleston-Sikeston
A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.

4. Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very good, (1,001 reviews)
Experience comfort at this Sikeston hotel, offering free breakfast and parking close to Central Park. The helpful staff welcomes guests to enjoy the indoor pool and fitness center. With easy access to Sikeston Depot Museum, you'll find everything needed for a convenient Missouri stay.
The price is $80
$91 total
includes taxes & fees
Nov 8 - Nov 9
Best Western Plus Sikeston I-55
An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.

5. Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.6 out of 10, Exceptional, (1,002 reviews)
Escape to this serene Sikeston hotel with both indoor and outdoor pools near restaurants and shopping. The fitness center, free breakfast, WiFi and parking enhance your stay, while the helpful staff ensures comfort just minutes from Central Park.
The price is $94
$108 total
includes taxes & fees
Nov 8 - Nov 9
Drury Inn & Suites Sikeston, MO
A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.

6. Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
2.0 star property
Sikeston
7.4 out of 10, Good, (1,001 reviews)
Travelers rave about this serene retreat with helpful staff and clean rooms. Take advantage of free WiFi, parking, and on-the-go breakfast. Work out in the fitness center before exploring Central Park and Sikeston Depot Museum nearby.
The price is $66
$76 total
includes taxes & fees
Nov 5 - Nov 6
Days Inn and Suites by Wyndham Sikeston
A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.

7. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very good, (829 reviews)
This peaceful hotel offers a complimentary continental breakfast, free WiFi, and convenient parking. Located near I-55 Exit 67, guests consistently praise the helpful staff and clean rooms that provide a quiet retreat after exploring local attractions.
The price is $69
$79 total
includes taxes & fees
Nov 3 - Nov 4
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
A hotel room with two beds, a desk, a chair, a TV, and a mirror.

8. Country Yard Inn and Suite

Country Yard Inn and Suite
2.0 star property
Sikeston
6.8 out of 10, Good, (163 reviews)
This welcoming motel offers convenience with complimentary WiFi and parking, plus round-the-clock front desk assistance. Explore nearby Central Park and Sikeston Depot Museum before returning to your comfortable accommodations.
The price is $57
$67 total
includes taxes & fees
Nov 3 - Nov 4
Country Yard Inn and Suite
A motel with a yellow exterior, a red roof, and a parking lot with several cars.

9. Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, Good, (107 reviews)
Active travelers will appreciate the health club at this comfortable Charleston motel. Free WiFi keeps you connected, while complimentary parking saves you money. Located within driving distance of Cape Girardeau Municipal Airport for easy regional access.
The price is $66
$74 total
includes taxes & fees
Nov 3 - Nov 4
Eagle Inn Charleston
A Comfort Inn & Suites hotel with a clear entrance, a covered parking area, and a sign indicating a 12' clearance.

10. Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very good, (322 reviews)
Warm comfort awaits at this Sikeston hotel where the indoor pool invites morning swims. Just minutes from Central Park and Sikeston Depot Museum, enjoy free WiFi, parking, and a fitness center while helpful staff enhance your stay.
The price is $87
$99 total
includes taxes & fees
Nov 22 - Nov 23
Comfort Inn & Suites Sikeston I-55
A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.

11. Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
2.0 star property
Sikeston
7.0 out of 10, Good, (695 reviews)
Cozy lodging near Central Park and Sikeston Depot Museum with complimentary breakfast, WiFi, and parking. Just 29 minutes from Cape Girardeau Municipal Airport, this Super 8 offers comfortable accommodations for exploring the area.
The price is $58
$66 total
includes taxes & fees
Nov 15 - Nov 16
Super 8 by Wyndham Sikeston/Miner Area
A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a painting on the wall.

12. La Center Motel

La Center Motel
2.0 star property
La Center
7.8 out of 10, Good, (24 reviews)
Escape to this relaxing La Center hotel with complimentary WiFi and parking. Just a 15-minute drive from Ohio River Valley and 16 minutes from Paducah Regional Airport, the convenient location makes exploring the area effortless.
The price is $60
$70 total
includes taxes & fees
Nov 3 - Nov 4
La Center Motel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Go beyond your typical stay in Wyatt

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Check out reviews of Wyatt hotels guests love

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
Sikeston

10/10 Exceptional

Food was very good both supper and breakfast. Our room rate was high compared to a couple just checking in before us WHY!! We booked room in September
United States
Judy
Reviewed January 31, 2025
Drury Inn & Suites Sikeston, MO

Frequently Asked Questions

What hotels do travelers like in Wyatt?

Guests like Super 8 by Wyndham Charleston/Sikeston East MO, The Riverstone Hotel Charleston-Sikeston and Quality Inn Cairo I-57.

Can I book refundable accommodations in Wyatt?

If you want the flexibility to change your plans to Wyatt, most hotels offer refundable* rates you can book. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.

What will the weather in Wyatt be like during my visit?

The warmest months in Wyatt are usually July and August with an average temp of 77°F. January and February are the chilliest months when the average temp is 41°F. The rainiest months are April and March.

Why should I book my Wyatt hotel with Hotels.com?

There are plenty of reasons to book your Wyatt travel with us: our free cancellations on selected hotels* gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.