Hotels in Prairie Home
Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices
Check prices for these dates
Where to stay in Prairie Home?
Days Inn by Wyndham Boonville
Days Inn by Wyndham Boonville
2.0 star property
Boonville
6.0 out of 10, (1003)
6.0/10
(1003)
- Enjoy a relaxing swim near Lions Park Aquatic Center and Boonville Museum.
The price is $42
$42
$47 total
includes taxes & fees
Dec 29 - Dec 30
Super 8 by Wyndham Boonville
Super 8 by Wyndham Boonville
2.5 star property
Boonville
6.4 out of 10, (653)
6.4/10
(653)
- Quiet retreat near Lions Park with free amenities for a peaceful Boonville stay.
The price is $62
$62
$70 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Baymont by Wyndham Columbia, MO
Baymont by Wyndham Columbia, MO
2.5 star property
Columbia
8.2 out of 10, Very Good, (635)
8.2/10
Very Good
(635)
- Wake up to free breakfast at this central hotel near University of Missouri.
The price is $59
$59
$66 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Quality Inn & Suites Boonville - Columbia
Quality Inn & Suites Boonville - Columbia
2.5 star property
Boonville
7.4 out of 10, Good, (579)
7.4/10
Good
(579)
- Experience comfort near Harley Park with an indoor pool and thoughtful amenities.
The price is $75
$75
$85 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Best Western Plus Columbia Inn
Best Western Plus Columbia Inn
2.5 star property
Columbia
8.8 out of 10, Excellent, (1205)
8.8/10
Excellent
(1205)
- Great for university visits and year-round comfort with attentive service.
The price is $70
$70
$79 total
includes taxes & fees
Dec 29 - Dec 30
Holiday Inn Express Boonville by IHG
Holiday Inn Express Boonville by IHG
2.5 star property
Boonville
8.6 out of 10, Excellent, (526)
8.6/10
Excellent
(526)
- Discover comfort close to Harley Park with indoor pool and fitness amenities.
The price is $100
$100
$128 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination
Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination
3.0 star property
Boonville
8.2 out of 10, Very Good, (950)
8.2/10
Very Good
(950)
- Great views of the Missouri River at this riverboat gaming hotel with live entertainment.
The price is $76
$76
$98 total
includes taxes & fees
Jan 26 - Jan 27, 2026
Drury Inn & Suites Columbia Stadium Boulevard
Drury Inn & Suites Columbia Stadium Boulevard
3.0 star property
Columbia
9.4 out of 10, Exceptional, (1003)
9.4/10
Exceptional
(1003)
The price is $90
$90
$102 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Country Inn & Suites by Radisson, Columbia, MO
Country Inn & Suites by Radisson, Columbia, MO
2.5 star property
Columbia
9.0 out of 10, Wonderful, (1719)
9.0/10
Wonderful
(1719)
The price is $78
$78
$88 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Quality Inn & Suites Columbia I-70
Quality Inn & Suites Columbia I-70
2.5 star property
Columbia
7.0 out of 10, Good, (807)
7.0/10
Good
(807)
- Quiet retreat near Mizzou with fitness center and seasonal pool offers relaxation.
The price is $53
$53
$60 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Wingate by Wyndham - Columbia
Wingate by Wyndham - Columbia
3.0 star property
Columbia
9.0 out of 10, Wonderful, (1210)
9.0/10
Wonderful
(1210)
- Stay close to University of Missouri with indoor pool and 24-hour fitness options.
The price is $81
$81
$92 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Super 8 by Wyndham Columbia East
Super 8 by Wyndham Columbia East
2.0 star property
Columbia
6.4 out of 10, (1001)
6.4/10
(1001)
- Experience Columbia's comfort at this convenient hotel with free perks and a pool.
The price is $54
$54
$61 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Ramada by Wyndham Columbia
Ramada by Wyndham Columbia
2.5 star property
Columbia
7.4 out of 10, Good, (1003)
7.4/10
Good
(1003)
The price is $65
$65
$73 total
includes taxes & fees
Dec 28 - Dec 29
Tru By Hilton Columbia South
Tru By Hilton Columbia South
2.5 star property
Columbia
The price is $93
$93
$107 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Wyndham Executive Center Columbia
Wyndham Executive Center Columbia
3.5 star property
Columbia
8.4 out of 10, Very Good, (1005)
8.4/10
Very Good
(1005)
The price is $85
$85
$96 total
includes taxes & fees
Jan 25 - Jan 26, 2026
Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG
Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG
2.5 star property
Columbia
8.8 out of 10, Excellent, (1000)
8.8/10
Excellent
(1000)
- Stay just 5 minutes from University of Missouri with hot tub and 24-hour fitness center.
The price is $99
$99
$112 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Red Roof Inn Columbia, MO
Red Roof Inn Columbia, MO
2.0 star property
Columbia
4.8 out of 10, (1004)
4.8/10
(1004)
- Stay in quiet comfort near University of Missouri at this clean, convenient hotel.
The price is $54
$54
$61 total
includes taxes & fees
Dec 28 - Dec 29
Iron Horse Hotel
Iron Horse Hotel
3.0 star property
Blackwater
9.6 out of 10, Exceptional, (117)
9.6/10
Exceptional
(117)
- Enjoy panoramic views from a charming rooftop terrace at this peaceful Blackwater haven.
The price is $129
$129
$140 total
includes taxes & fees
Dec 28 - Dec 29
Boonville Luxury Lodging
Boonville Luxury Lodging
4.0 star property
Boonville
10.0 out of 10, Exceptional, (40)
10/10
Exceptional
(40)
- Charming B&B near Isle of Capri Casino with gourmet local breakfast provided daily.
The price is $197
$197
$223 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Extended Stay America Select Suites - Columbia - Stadium Blvd.
Extended Stay America Select Suites - Columbia - Stadium Blvd.
2.5 star property
Columbia
7.0 out of 10, Good, (1002)
7.0/10
Good
(1002)
- Extended stay rooms near University of Missouri with free parking.
The price is $77
$77
$87 total
includes taxes & fees
Jan 17 - Jan 18, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Prairie Home
Pet friendly
Family friendly
Check out reviews of Prairie Home hotels guests love
Country Inn & Suites by Radisson, Columbia, MO
10/10 Excellent
"Great and friendly check in"
Baymont by Wyndham Columbia, MO
10/10 Excellent
"We had a great stay at this place. We tend to drive between Denver and St. Louis area often, and it’s nice to have this place on our list of approved places. You can tell they really care about providing a nice place to stay."
Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination
10/10 Excellent
"Yes, the room nice, comfortable and clean. The staffs were very nice with good costumer services. I surely recommend this property to a friend or family member."
Wingate by Wyndham - Columbia
10/10 Excellent
"Clean room, helpful staff, room was noisy at night due to traffic outside but other than that great for the price."
Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG
10/10 Excellent
"Very clean hotel with friendly staff"
Drury Plaza Hotel Columbia East
10/10 Excellent
"Spotless room, friendly staff, wonderful food for a family with younger children. "
Staybridge Suites Columbia by IHG
10/10 Excellent
"Comfortable stay. Pleasant staff. Great breakfast. "
Drury Inn & Suites Columbia Stadium Boulevard
10/10 Excellent
"Such a great orient"
Stoney Creek Hotel Columbia
10/10 Excellent
"noce atmosphere"
Frequently asked questions
Can I book a refundable hotel in Prairie Home?
If you want the flexibility to change your travel plans to Prairie Home, most properties provide refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.
What will the weather in Prairie Home be like during my trip?
The warmest months in Prairie Home are usually July and August with an average temp of 75°F. January and February are the chilliest months when the average temp is 36°F. The rainiest months are May and April.
Why should I book my Prairie Home hotel with Hotels.com?
There are plenty of reasons to book your Prairie Home travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.