Hotels in La Mesa

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Check prices for these dates

Tonight
Aug 21 - Aug 22
Tomorrow
Aug 22 - Aug 23
This weekend
Aug 21 - Aug 23
Next weekend
Aug 28 - Aug 30

Where to stay in La Mesa?

A hotel courtyard with outdoor seating, palm trees, and a view of the ocean at dusk.
A marina with multiple boats docked and tall buildings in the background.
A grocery store with refrigerated sections for beverages, shelves with snacks, and a display of packaged goods.
A high-rise urban area with modern buildings, palm trees, and a clear sky.

Wyndham San Diego Bayside

Wyndham San Diego Bayside
Downtown San Diego
$152
$211 total
includes taxes & fees
Aug 24 - Aug 25
Wyndham San Diego Bayside
A Hard Rock Hotel with a prominent Hard Rock Cafe sign, a large marquee, and a modern building facade.
An outdoor dining area with tables and chairs, a menu stand, and a view of a street with palm trees and a building in the background.
A modern lobby with a digital display wall, reception desks, and a spacious, well-lit area.

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego
Downtown San Diego
$184
$261 total
includes taxes & fees
Sep 13 - Sep 14
Hard Rock Hotel San Diego
A multi-story hotel with a brick facade, multiple windows, and a fire escape.
A Starbucks with a modern interior, including a wooden wall and a counter with a coffee machine.
A lobby with a seating area featuring two armchairs and a table, a decorative wall, and a chandelier.
A hotel room with a large walk-in closet, a bed with white bedding, a bedside table with a lamp, and a wall-mounted mirror.

The Sofia Hotel

The Sofia Hotel
Downtown San Diego
$181
$237 total
includes taxes & fees
Aug 26 - Aug 27
The Sofia Hotel
A hotel room with a large window offering a city view, a bed, a chair, and a small table.
A modern reception area with a wooden reception desk, a large flat-screen TV displaying a scenic ocean view, and a seating area with pink chairs.
A room with a view of a cityscape, a chair with a patterned cushion, and a floor lamp.
A tall, modern hotel with a curved facade, multiple balconies, and an American flag.

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection
Downtown San Diego
$139
$162 total
includes taxes & fees
Sep 7 - Sep 8
The DEXTRO Little Italy, BW Premier Collection
A pathway flanked by neatly trimmed hedges and a building with a balcony.
A courtyard with a small pond, trees, and a fountain.
A courtyard with a small pond, palm trees, and a building with balconies.
A lobby with a mosaic fountain, seating area, and a book display.

California Suites Hotel

California Suites Hotel
Clairemont
$89
$102 total
includes taxes & fees
Aug 23 - Aug 24
California Suites Hotel
A resort with a large swimming pool surrounded by lounge chairs and palm trees.
A hotel with a curved entrance, palm trees, and a parking lot.
A lobby with seating areas, a piano, and a reception desk.
A spacious lobby with a central round table, a reception desk, and a bar area.

Handlery Hotel

Handlery Hotel
Mission Valley
$119
$137 total
includes taxes & fees
Aug 26 - Aug 27
Handlery Hotel
A cityscape at dusk with illuminated buildings and a bridge in the distance.
A high-rise hotel with multiple floors, a prominent entrance, and a view of the surrounding cityscape and waterfront.
A rooftop pool area with lounge chairs and umbrellas, surrounded by modern buildings and a cityscape at sunset.
A modern hotel lobby with a wooden reception desk, a patterned wall, and a long corridor leading to a bright area with a view.

Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy
Downtown San Diego
$161
$187 total
includes taxes & fees
Aug 30 - Aug 31
Courtyard by Marriott San Diego Downtown Little Italy
A rectangular swimming pool with lounge chairs and umbrellas, surrounded by tall trees and greenery.
A hotel room with a large bed, a TV, a desk, and a painting on the wall.
A hotel room with a large window with blinds, a round mirror, two teal chairs, a small round table, and a television on a wooden cabinet.
A compact kitchen with a microwave, coffee maker, and sink.

Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle
Mission Valley
$88
$102 total
includes taxes & fees
Sep 7 - Sep 8
Days Inn by Wyndham San Diego Hotel Circle
A pool area with a hot tub, lounge chairs, and umbrellas.
An outdoor seating area with a fire pit table, surrounded by chairs and umbrellas, in a courtyard with palm trees and a building in the background.
A marina with boats, a bridge, and a building with a pool and palm trees.
A hotel room with a bed, a lamp, and a box of pizza.

The Dana on Mission Bay

The Dana on Mission Bay
Mission Bay
$169
$223 total
includes taxes & fees
Aug 30 - Aug 31
The Dana on Mission Bay
A waterfront hotel with a dock, palm trees, and a view of the water.
A modern building with a curved roof, surrounded by lush tropical vegetation.
An outdoor dining area with tables and chairs, umbrellas, and string lights against a sunset backdrop.

Paradise Point Resort & Spa

Paradise Point Resort & Spa
Mission Bay
$215
$300 total
includes taxes & fees
Sep 7 - Sep 8
Paradise Point Resort & Spa
A hotel lobby with a 'Lobby' sign, palm trees, and a sunset sky.
A modern hotel lobby with a reception desk, seating area with chairs and a sofa, a ceiling fan, and a large window with curtains.
A restaurant with a bar area, booths, and a view of the sunset through large windows.
An outdoor patio area with tables and chairs, red umbrellas, and a view of palm trees and a building with a 'BLW' sign.

Best Western Seven Seas

Best Western Seven Seas
Mission Valley
$85
$97 total
includes taxes & fees
Aug 30 - Aug 31
Best Western Seven Seas
A bar area with a glass ceiling, a central bar counter, and multiple stools.
A large swimming pool with lounge chairs and umbrellas, surrounded by palm trees and a building with a striped facade.
A luxurious interior with a large chandelier, patterned sofas, and a view of a cityscape through a large window.
A dimly lit room with patterned walls, a wooden table, and a chair.

Lafayette Hotel & Club

Lafayette Hotel & Club
University Heights
$249
$286 total
includes taxes & fees
Sep 7 - Sep 8
Lafayette Hotel & Club
A spacious lobby with modern furniture, large windows, and a high ceiling with hanging lights.
A swimming pool with blue lounge chairs and umbrellas, surrounded by a building with balconies.
A hotel room with a large bed, a wooden nightstand, a bench, a desk with a TV, and a chair.
A pathway leading to a building labeled "LEGACY Hotel."

Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
Mission Valley
$192
$221 total
includes taxes & fees
Aug 30 - Aug 31
Legacy Resort Hotel & Spa
An aerial view of a resort with multiple swimming pools, lounge areas, and palm trees.
A modern hotel with a prominent circular tower and a glass facade.
A bar area with a long counter, multiple stools, and hanging wicker lamps.
A marina with numerous boats docked, a large ship in the background, and a modern building with balconies.

Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina
Downtown San Diego
$216
$298 total
includes taxes & fees
Sep 7 - Sep 8
Marriott Marquis San Diego Marina
An outdoor dining area with tables and chairs, overlooking a beach and ocean.
A serene garden with a pond, lush greenery, and a gazebo.
A large, multi-deck riverboat with a white exterior and multiple levels of balconies.
A waterfront property with a pathway lined by palm trees and string lights, leading to a building with a dock and boats.

Bahia Resort Hotel

Bahia Resort Hotel
Central Mission Beach
$199
$284 total
includes taxes & fees
Sep 20 - Sep 21
Bahia Resort Hotel
A hotel breakfast area with a long counter displaying various food items, including fruits, pastries, and a coffee station.
A reception area with a modern design, featuring a reception desk, a check-in counter, and a wall-mounted sign indicating check-in and check-out times.
A hotel room with a large bed, a TV, a desk with a lamp, and a bookshelf.
A swimming pool with lounge chairs, palm trees, and a building in the background.

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
Mission Valley
$151
$174 total
includes taxes & fees
Aug 31 - Sep 1
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
A modern indoor swimming pool with lounge chairs and palm trees.
A modern bar area with a curved counter, bar stools, and a large chandelier.
A spacious outdoor lounge area with seating arrangements, a fire feature, and a view of the sunset.
A marina with boats, a modern building, and a sunset.

Hilton San Diego Bayfront

Hilton San Diego Bayfront
Downtown San Diego
$155
$229 total
includes taxes & fees
Sep 7 - Sep 8
Hilton San Diego Bayfront
A modern lobby with a stone wall, blue sofas, a reception desk, and a staircase.
A bar area with three cocktails on a wooden bar counter.
A lobby with a stone wall, blue sofa, purple chairs, and a patterned rug.
A hotel pool area with a circular pool, lounge chairs, umbrellas, and palm trees.

Kings Inn San Diego

Kings Inn San Diego
Mission Valley
$108
$124 total
includes taxes & fees
Aug 24 - Aug 25
Kings Inn San Diego
A modern bar area with a curved counter, multiple bar stools, and a large window offering a view of the cityscape.
A spacious lobby with large windows, curved ceiling, and comfortable seating areas.
An outdoor patio area with seating arrangements, including sofas, chairs, and round tables.
A spacious lobby with a high ceiling, a large sectional sofa, multiple seating areas, and a modern chandelier.

Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark
Downtown San Diego
$127
$193 total
includes taxes & fees
Sep 7 - Sep 8
Omni San Diego Hotel at the Ballpark
A restaurant with outdoor seating, brick walls, and decorative lighting.
A spacious lobby with a bar area, seating arrangements, and a large chandelier.
A spacious lobby with high ceilings, large windows, and elegant furniture.
A spacious lobby with a high ceiling, large windows, and a central chandelier.

The Horton Grand, Downtown/Gaslamp Quarter

The Horton Grand, Downtown/Gaslamp Quarter
Downtown San Diego
$152
$204 total
includes taxes & fees
Aug 23 - Aug 24
The Horton Grand, Downtown/Gaslamp Quarter
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Our prices for hotels in La Mesa are cheapest in January
Price trends for hotels in La Mesa
Pricing is based on two traveler single night rates
View properties in August
Typical weather for La Mesa
August
High 29°C / low 20°C. Sunny most days.
View properties in August
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Monthly weather averages (˚C)

Top neighborhoods in La Mesa

A town with a mountain in the background, a clear sky, and scattered clouds.
A town with a mountain in the background.

Casa de Oro-Mount Helix

La Mesa's Casa de Oro-Mount Helix neighborhood offers attractions including Mount Helix Park.

A large white cross against a cloudy sky.

Mount Helix

The Mount Helix neighborhood offers attractions such as Mount Helix Park and FAITH CHAPEL.

Top landmarks in La Mesa

Mount Helix Park

7.4/10 (59 reviews)
If you're planning a bit of sightseeing head to Mount Helix Park— just one of the monuments in Casa de Oro-Mount Helix. Why not take a stroll along the port and watch the sunset while you're here? La Mesa has other landmarks you might want to visit such as Hotel del Coronado.
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FAITH CHAPEL

FAITH CHAPEL is a venue in Mount Helix.
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Computer Museum of America

6.6/10 (36 reviews)
Computer Museum of America is 1 mi (1.6 km) from central La Mesa, why not stop by during your stay. Hotels.com travelers also say the area is walkable and has lots of nice beaches. If you want to experience more of the culture La Mesa has to offer, head to San Diego State University, Sharp Grossmont Hospital, and Cal Coast Credit Union Open Air Theater.
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La Mesa Memorial Fine Arts Center

La Mesa Memorial Fine Arts Center is in the heart of La Mesa, so why not stop by during your stay. If you have fun at La Mesa Memorial Fine Arts Center, you'll love Computer Museum of America, located nearby.
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The Bancroft

If you find yourself in Mount Helix, you can stop off for a few drinks or snacks at The Bancroft.
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Learn more about La Mesa

Between the bustle of San Diego and the quiet of the hills, La Mesa lives up to its 'Jewel of the Hills' nickname without trying too hard. The historic Village area offers boutiques and cafés where locals actually eat, not just places that survive on tourist traffic. Mount Helix rewards a short climb with panoramic views that explain why everyone in California seems suspiciously content. Lake Murray Park provides a refreshing escape where fishing lines dangle alongside kayakers who've discovered this urban oasis. Train enthusiasts find unexpected delight at the Pacific Southwest Railway Museum, where vintage locomotives sit frozen in time.

See all hotels in La Mesa
A sunset over a mountainous landscape with scattered clouds.

Check out reviews of La Mesa hotels guests love

Wyndham San Diego Bayside

Wyndham San Diego Bayside

10/10 Excellent
"Did not like to pay for Handicap parking."
Len 4-night trip
Posted less than an hour ago
Wyndham San Diego Bayside
Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy

8/10 Good
"Spacious clean rooms with comfortable beds. Walking distance to great restaurants. It was a little loud being so close to the freeway and the parking garage ramps are tight for bigger vehicles."
Alejandro 3-night trip
Posted less than an hour ago
Courtyard by Marriott San Diego Downtown Little Italy
Bay Club Hotel & Marina

Bay Club Hotel & Marina

10/10 Excellent
"Great hotel! Super clean, super friendly staff! We will be back and recommending this place to anyone coming to San Diego!"
Staci 1-night trip
Posted 1 hour ago
Bay Club Hotel & Marina
California Suites Hotel

California Suites Hotel

10/10 Excellent
"So aside from this place being super affordable, I’ve been to a few places where they charge more but got less. The staff here is very helpful and friendly, and I would recommend it especially if you’re on a budget."
Mathew 4-night trip
Posted 5 hours ago
California Suites Hotel
Gaylord Pacific Resort & Convention Center

Gaylord Pacific Resort & Convention Center

10/10 Excellent
"Excellent!"
Pratik 3-night trip
Posted 5 hours ago
Gaylord Pacific Resort & Convention Center
Sheraton San Diego Resort

Sheraton San Diego Resort

10/10 Excellent
"This is a beautiful property with an abundant of activities."
Jo 3-night trip
Posted 6 hours ago
Sheraton San Diego Resort
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

10/10 Excellent
"We had difficulty getting food. Mary Jane’s was closed early and the 207 bar didn’t open til late. There was nothing mid day available when we arrived"
Diane 1-night trip
Posted 7 hours ago
Hard Rock Hotel San Diego
The Dana on Mission Bay

The Dana on Mission Bay

8/10 Good
"Overall good location. I prefer the bay side to the boat dock side. The rooms are larger and nicer. It was very annoying that they charge guest an added 6% to their checks if you eat at the Firefly restaurant. That’s so weird. Never seen that before. I would’ve eaten off property if I had known that ."
Falana 1-night trip
Posted 7 hours ago
The Dana on Mission Bay
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

10/10 Excellent
"It’s was great"
Darryus 7-night trip
Posted 1 day ago
Days Inn by Wyndham San Diego Hotel Circle

Frequently asked questions

What accommodations do travelers like in La Mesa?
Guests like Manchester Grand Hyatt San Diego, Wyndham San Diego Bayside and California Suites Hotel.
Can I book a refundable accommodation in La Mesa?
If you need the flexibility to change your travel plans to La Mesa, most hotels offer refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in La Mesa if I want a vacation home instead of a hotel?
If you're looking for a good alternative to a hotel, review our selection of 60 vacation homes. In addition, you can choose from 7 apartments.
What will the weather in La Mesa be like during my trip?
August and September are typically the warmest months in La Mesa when the average temp is 72°F. February and January are the coldest months when the average temperature is 56°F. December and February are the months with the most rain.
Why should I book my La Mesa hotel through Hotels.com?
There are lots of reasons to book your La Mesa trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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