Hotels in Cape Girardeau

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Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (173 reviews)
Discover Cape Girardeau from this hotel with free WiFi, parking, and continental breakfast. Take a refreshing dip in the indoor pool after exploring nearby attractions like Fort D Historic Site and Cape Splash Family Aquatic Center.
The price is $84
$95 total
includes taxes & fees
Apr 26 - Apr 27
Fairfield Inn & Suites by Marriott Cape Girardeau
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,002 reviews)
Located minutes from Shawnee National Forest, this hotel offers a refreshing indoor pool and hot tub for unwinding after adventures. Enjoy complimentary breakfast, WiFi, and parking while being close to Cape Splash Family Aquatic Center.
The price is $100
$113 total
includes taxes & fees
May 3 - May 4
Drury Plaza Hotel Cape Girardeau Conference Center
Tru By Hilton Cape Girardeau
Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (120 reviews)
This Cape Girardeau hotel offers convenient access to Shawnee National Forest and local nature attractions. Start each morning with free breakfast before exploring nearby conservation areas, then return for a swim in the indoor pool or a workout at the fitness center.
The price is $98
$111 total
includes taxes & fees
Apr 22 - Apr 23
Tru By Hilton Cape Girardeau
Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1,000 reviews)
This tranquil hotel provides easy access to Cape Splash Family Aquatic Center and Conservation Nature Center. Enjoy complimentary breakfast, WiFi, and parking, with helpful staff ensuring a relaxing atmosphere near local restaurants and shopping.
The price is $72
$81 total
includes taxes & fees
Apr 20 - Apr 21
Pear Tree Inn Cape Girardeau West
Quality Inn Cape Girardeau North
Quality Inn Cape Girardeau North
2.5 star property
Cape Girardeau
7.2 out of 10, Good, (727 reviews)
Escape to this welcoming hotel featuring an outdoor pool and free daily English breakfast. Just minutes from Mississippi River and popular attractions, with free WiFi and parking. Guests rave about the helpful staff ready to make your stay enjoyable.
The price is $67
$75 total
includes taxes & fees
Apr 23 - Apr 24
Quality Inn Cape Girardeau North
Rockwood Inn
Rockwood Inn
2.0 star property
Cape Girardeau
10.0 out of 10, Exceptional, (20 reviews)
Wake up refreshed at this cozy Cape Girardeau retreat with free WiFi and parking. Explore nearby attractions like Show Me Center and Isle Casino, then unwind in the tranquil garden after your adventures.
The price is $150
$170 total
includes taxes & fees
Apr 19 - Apr 20
Rockwood Inn
The Riverview
The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (548 reviews)
Overlooking the Mississippi River, this hotel puts you near Isle Casino Cape Girardeau and Riverfront Park. Enjoy 2 restaurants including Beacon 53, plus free WiFi and complimentary parking during your business-friendly stay.
The price is $132
$149 total
includes taxes & fees
Apr 20 - Apr 21
The Riverview
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,000 reviews)
Discover Cape Girardeau from this central hotel with easy access to restaurants and shopping. Enjoy the indoor pool and fitness center, then wake up to a free breakfast. Helpful staff ensure a smooth stay with convenient free WiFi and parking.
The price is $102
$115 total
includes taxes & fees
May 17 - May 18
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Town House Inn Cape Giradreau
Town House Inn Cape Giradreau
2.5 star property
Cape Girardeau
6.2 out of 10, (216 reviews)
Wake up to adventure at this Cape Girardeau motel near the Family Aquatic Center and Show Me Center. Enjoy hassle-free travel with free WiFi, complimentary parking, and 24-hour front desk service for your Missouri getaway.
The price is $75
$88 total
includes taxes & fees
Apr 19 - Apr 20
Town House Inn Cape Giradreau
Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,005 reviews)
Peaceful retreat in Cape Girardeau with shopping and restaurants within walking distance. Start your day with free breakfast before enjoying the indoor pool, then unwind in the hot tub. Near Cape Splash Family Aquatic Center with free WiFi and parking.
The price is $90
$102 total
includes taxes & fees
May 3 - May 4
Drury Inn & Suites Cape Girardeau
Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (804 reviews)
Wake up to a free breakfast at this Cape Girardeau hotel, just minutes from Shawnee National Forest and the Mississippi River. Swim in the indoor pool, work out in the fitness center, or relax on the terrace after exploring nearby aquatic attractions.
The price is $106
$119 total
includes taxes & fees
Apr 23 - Apr 24
Hampton Inn Cape Girardeau I 55 East
Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (502 reviews)
Experience Mississippi River views and explore Shawnee National Forest from this downtown Marriott. The Bistro serves American cuisine while in-room refrigerators and washers/dryers enhance comfort. Enjoy the 24-hour fitness center after visiting nearby Riverfront Park and Isle Casino.
The price is $130
$147 total
includes taxes & fees
May 10 - May 11
Courtyard by Marriott Cape Girardeau Downtown
Candlewood Suites Cape Girardeau by IHG
Candlewood Suites Cape Girardeau by IHG
2.5 star property
Cape Girardeau
8.0 out of 10, Very Good, (918 reviews)
The price is $80
$96 total
includes taxes & fees
Apr 26 - Apr 27
Candlewood Suites Cape Girardeau by IHG
Makanda Inn
Makanda Inn
3.5 star property
Makanda
10.0 out of 10, Exceptional, (36 reviews)
Tucked near a train station in Makanda, this B&B offers a tranquil escape with massage services and a welcoming bar. Explore nearby Makanda Boardwalk after breakfast, then unwind on the terrace as forest sounds serenade your evening.
The price is $262
$299 total
includes taxes & fees
Apr 20 - Apr 21
Makanda Inn
Hotel 7 Inn Anna
Hotel 7 Inn Anna
2.5 star property
Anna
6.6 out of 10, (220 reviews)
Unwind in this quiet hotel with both indoor and outdoor swimming options. Located near Anna City Park and Lincoln Heritage Winery, guests enjoy free breakfast, WiFi, and parking. The helpful staff and fitness center complete your peaceful stay.
The price is $91
$106 total
includes taxes & fees
Apr 19 - Apr 20
Hotel 7 Inn Anna
Comfort Suites Jackson-Cape Girardeau
Comfort Suites Jackson-Cape Girardeau
2.5 star property
Jackson
8.2 out of 10, Very Good, (760 reviews)
Begin your day with a complimentary breakfast at this Jackson hotel near Mississippi River and Shawnee National Forest. The indoor pool offers year-round swimming while free WiFi and parking add value. Cape Girardeau Conservation Nature Center awaits nearby.
The price is $92
$100 total
includes taxes & fees
Apr 22 - Apr 23
Comfort Suites Jackson-Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
9.0 out of 10, Wonderful, (746 reviews)
The price is $89
$96 total
includes taxes & fees
Apr 20 - Apr 21
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1,005 reviews)
This peaceful Jackson hotel features a relaxing hot tub and indoor swimming pool. Free breakfast, WiFi, and parking add value, while the helpful staff ensures a comfortable stay. Litz Park and Lazy L Safari Park are nearby attractions to explore.
The price is $80
$85 total
includes taxes & fees
Apr 27 - Apr 28
Drury Inn & Suites Jackson MO
EC Reed's Mercantile and Hotel
EC Reed's Mercantile and Hotel
3.0 star property
Marble Hill
9.6 out of 10, Exceptional, (85 reviews)
Adventure seekers can explore nearby hiking trails, kayaking, and rafting, then return to this welcoming hotel. Enjoy free continental breakfast, WiFi, and parking, plus exceptional service from the staff that guests consistently praise.
The price is $93
$102 total
includes taxes & fees
Apr 19 - Apr 20
EC Reed's Mercantile and Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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When is the best time to visit Cape Girardeau?

Our prices for hotels in Cape Girardeau are cheapest in December
Price trends for hotels in Cape Girardeau
Pricing is based on two traveler single night rates
View properties in April
Currently viewing crowd sizes and weather for April.
Typical weather for Cape Girardeau
April
High 19°C / low 9°C. Sunny most days.
View properties in April
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April, no crowd data, average high temperature 19 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
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May, no crowd data, average high temperature 25 degrees Celsius, average low temperature 15 degrees Celsius. Sunny most days.
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June, no crowd data, average high temperature 30 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
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32°
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July, no crowd data, average high temperature 32 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
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31°
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August, no crowd data, average high temperature 31 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
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28°
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September, no crowd data, average high temperature 28 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
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21°
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October, no crowd data, average high temperature 21 degrees Celsius, average low temperature 11 degrees Celsius. Sunny most days.
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13°
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November, no crowd data, average high temperature 13 degrees Celsius, average low temperature 4 degrees Celsius. Partly sunny.
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December, no crowd data, average high temperature 9 degrees Celsius, average low temperature 1 degrees Celsius. Partly sunny.
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January, no crowd data, average high temperature 6 degrees Celsius, average low temperature -2 degrees Celsius. Partly sunny.
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February, no crowd data, average high temperature 8 degrees Celsius, average low temperature -1 degrees Celsius. Partly sunny.
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14°
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March, no crowd data, average high temperature 14 degrees Celsius, average low temperature 5 degrees Celsius. Sunny most days.
Monthly weather averages (˚C)

Top landmarks in Cape Girardeau

Learn more about Cape Girardeau

Hugging the Mississippi River, this college town reveals its history through vibrant floodwall murals that transform concrete into an outdoor gallery. Southeast Missouri State University brings youthful energy to streets lined with locally-owned shops and cafes. The River Campus hosts performances in a former seminary with river views. Explore the Cape Girardeau Conservation Nature Center or paddle the Mississippi. Trail of Tears State Park offers hiking paths with panoramic vistas that explain why settlers chose this dramatic spot. The Cape Riverfront Market buzzes with farmers and artisans, while the historic downtown invites exploration with red-brick buildings housing quirky boutiques and restaurants serving hearty Midwestern fare with surprising sophistication.

Bill Emerson Memorial Bridge, Cape Girardeau, MO

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Frequently asked questions

What hotels do travelers recommend in Cape Girardeau?
Can I book a refundable hotel in Cape Girardeau?
If you need the flexibility to change your travel plans to Cape Girardeau, most accommodations offer refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.
Where can I stay in Cape Girardeau if I'm looking for an affordable accommodation?
Where can I stay in Cape Girardeau if I want a vacation rental instead of a hotel?
If you want a good alternative to a hotel, look over our selection of 21 vacation homes. In addition, you can choose from 22 apartments.
What will the weather in Cape Girardeau be like during my vacation?
July and August are typically the warmest months in Cape Girardeau when the average temp is 76°F. January and February are the coldest months when the average temperature is 40°F. April and March are the months with the most rain.
Why should I book my Cape Girardeau hotel through Hotels.com?
There are lots of reasons to book your Cape Girardeau trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.