Hotels in Sikeston

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This weekend
May 22 - May 24
Next weekend
May 29 - May 31

Where to stay in Sikeston?

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Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1,005 reviews)
This peaceful Jackson hotel features a relaxing hot tub and indoor swimming pool. Free breakfast, WiFi, and parking add value, while the helpful staff ensures a comfortable stay. Litz Park and Lazy L Safari Park are nearby attractions to explore.
The price is $80
$85 total
includes taxes & fees
May 25 - May 26
Drury Inn & Suites Jackson MO
Lobby

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,000 reviews)
Located minutes from Shawnee National Forest, this hotel offers a refreshing indoor pool and hot tub for unwinding after adventures. Enjoy complimentary breakfast, WiFi, and parking while being close to Cape Splash Family Aquatic Center.
The price is $100
$113 total
includes taxes & fees
May 25 - May 26
Drury Plaza Hotel Cape Girardeau Conference Center
Exterior

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,000 reviews)
Discover Cape Girardeau from this central hotel with easy access to restaurants and shopping. Enjoy the indoor pool and fitness center, then wake up to a free breakfast. Helpful staff ensure a smooth stay with convenient free WiFi and parking.
The price is $110
$124 total
includes taxes & fees
May 24 - May 25
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Free daily buffet breakfast

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,003 reviews)
Peaceful retreat in Cape Girardeau with shopping and restaurants within walking distance. Start your day with free breakfast before enjoying the indoor pool, then unwind in the hot tub. Near Cape Splash Family Aquatic Center with free WiFi and parking.
The price is $90
$102 total
includes taxes & fees
May 31 - Jun 1
Drury Inn & Suites Cape Girardeau
Lobby

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (186 reviews)
Discover Cape Girardeau from this hotel with free WiFi, parking, and continental breakfast. Take a refreshing dip in the indoor pool after exploring nearby attractions like Fort D Historic Site and Cape Splash Family Aquatic Center.
The price is $84
$95 total
includes taxes & fees
May 28 - May 29
Fairfield Inn & Suites by Marriott Cape Girardeau
Exterior

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
9.0 out of 10, Wonderful, (767 reviews)
The price is $93
$100 total
includes taxes & fees
May 24 - May 25
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
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Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (815 reviews)
Wake up to a free breakfast at this Cape Girardeau hotel, just minutes from Shawnee National Forest and the Mississippi River. Swim in the indoor pool, work out in the fitness center, or relax on the terrace after exploring nearby aquatic attractions.
The price is $106
$119 total
includes taxes & fees
May 31 - Jun 1
Hampton Inn Cape Girardeau I 55 East
Snack bar

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (127 reviews)
This Cape Girardeau hotel offers convenient access to Shawnee National Forest and local nature attractions. Start each morning with free breakfast before exploring nearby conservation areas, then return for a swim in the indoor pool or a workout at the fitness center.
The price is $93
$105 total
includes taxes & fees
Jun 14 - Jun 15
Tru By Hilton Cape Girardeau
Desk, laptop workspace, blackout drapes, free cribs/infant beds

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1,000 reviews)
This tranquil hotel provides easy access to Cape Splash Family Aquatic Center and Conservation Nature Center. Enjoy complimentary breakfast, WiFi, and parking, with helpful staff ensuring a relaxing atmosphere near local restaurants and shopping.
The price is $72
$81 total
includes taxes & fees
May 24 - May 25
Pear Tree Inn Cape Girardeau West
Lobby sitting area

The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (412 reviews)
The price is $70
$78 total
includes taxes & fees
May 22 - May 23
The Riverstone Hotel Charleston-Sikeston
Indoor pool, outdoor pool

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.6 out of 10, Exceptional, (1,001 reviews)
Escape to this serene Sikeston hotel with both indoor and outdoor pools near restaurants and shopping. The fitness center, free breakfast, WiFi and parking enhance your stay, while the helpful staff ensures comfort just minutes from Central Park.
The price is $111
$128 total
includes taxes & fees
May 25 - May 26
Drury Inn & Suites Sikeston, MO
Lobby sitting area

The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (575 reviews)
Overlooking the Mississippi River, this hotel puts you near Isle Casino Cape Girardeau and Riverfront Park. Enjoy 2 restaurants including Beacon 53, plus free WiFi and complimentary parking during your business-friendly stay.
The price is $132
$149 total
includes taxes & fees
May 25 - May 26
The Riverview
Lobby

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (508 reviews)
Experience Mississippi River views and explore Shawnee National Forest from this downtown Marriott. The Bistro serves American cuisine while in-room refrigerators and washers/dryers enhance comfort. Enjoy the 24-hour fitness center after visiting nearby Riverfront Park and Isle Casino.
The price is $125
$142 total
includes taxes & fees
May 30 - May 31
Courtyard by Marriott Cape Girardeau Downtown
Free daily full breakfast

Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very Good, (1,013 reviews)
Experience comfort at this Sikeston hotel, offering free breakfast and parking close to Central Park. The helpful staff welcomes guests to enjoy the indoor pool and fitness center. With easy access to Sikeston Depot Museum, you'll find everything needed for a convenient Missouri stay.
The price is $90
$103 total
includes taxes & fees
Jun 7 - Jun 8
Best Western Plus Sikeston I-55
Exterior

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (462 reviews)
Experience Sikeston from this hotel with free breakfast, WiFi, and parking. Take a morning dip in the indoor pool or hit the fitness center. Near Central Park and Sikeston Depot Museum, guests love the helpful staff and clean rooms.
The price is $107
$121 total
includes taxes & fees
May 31 - Jun 1
Holiday Inn Express & Suites Sikeston Southwest by IHG
Property amenity

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (80 reviews)
Located in Sikeston, this hotel offers free breakfast, WiFi, and parking. Take a refreshing swim in the indoor pool or grab a bite at the restaurant. Nearby attractions include Central Park and Sikeston Depot Museum for local exploration.
The price is $110
$125 total
includes taxes & fees
May 28 - May 29
Fairfield Inn & Suites by Marriott Sikeston
Exterior

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (562 reviews)
Dive into vacation mode at this welcoming hotel with an indoor pool and fitness center near Central Park. After enjoying the complimentary breakfast, explore Sikeston Depot Museum before returning to relax in modern rooms with free WiFi.
The price is $102
$115 total
includes taxes & fees
May 31 - Jun 1
Hampton Inn Sikeston
Individually decorated, individually furnished, desk, blackout drapes

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very Good, (780 reviews)
This peaceful hotel offers a complimentary continental breakfast, free WiFi, and convenient parking. Located near I-55 Exit 67, guests consistently praise the helpful staff and clean rooms that provide a quiet retreat after exploring local attractions.
The price is $67
$77 total
includes taxes & fees
May 21 - May 22
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Laptop workspace, blackout drapes, free cribs/infant beds, free WiFi

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.6 out of 10, (634 reviews)
This Charleston motel offers complimentary WiFi, parking, and on-the-go breakfast daily. Located with convenient interstate access to Cape Girardeau, guests consistently praise the helpful staff. The comfortable accommodations provide a practical base for exploring southeastern Missouri.
The price is $60
$66 total
includes taxes & fees
Jun 7 - Jun 8
Super 8 by Wyndham Charleston/Sikeston East MO
Lobby

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
2.5 star property
Cape Girardeau
7.2 out of 10, Good, (744 reviews)
Escape to this welcoming hotel featuring an outdoor pool and free daily English breakfast. Just minutes from Mississippi River and popular attractions, with free WiFi and parking. Guests rave about the helpful staff ready to make your stay enjoyable.
The price is $67
$75 total
includes taxes & fees
May 26 - May 27
Quality Inn Cape Girardeau North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Check out pet-friendly hotels in Sikeston

Exterior
Hampton Inn Sikeston

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (562)
The price is $102
$115 total
includes taxes & fees
May 31 - Jun 1
Hampton Inn Sikeston
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You may also like hotels with pools in Sikeston

Exterior
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1000)
The price is $110
$124 total
includes taxes & fees
May 24 - May 25
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
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You can also stay at family-friendly hotels in Sikeston

Indoor pool, outdoor pool
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.6 out of 10, Exceptional, (1001)
The price is $111
$128 total
includes taxes & fees
May 25 - May 26
Drury Inn & Suites Sikeston, MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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When is the best time to visit Sikeston?

Our prices for hotels in Sikeston are cheapest in December
Price trends for hotels in Sikeston
Pricing is based on two traveler single night rates
View properties in May
Currently viewing crowd sizes and weather for May.
Typical weather for Sikeston
May
High 25°C / low 16°C. Sunny most days.
View properties in May
25°
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May, no crowd data, average high temperature 25 degrees Celsius, average low temperature 16 degrees Celsius. Sunny most days.
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30°
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June, no crowd data, average high temperature 30 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
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32°
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July, no crowd data, average high temperature 32 degrees Celsius, average low temperature 22 degrees Celsius. Sunny most days.
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31°
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August, no crowd data, average high temperature 31 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
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28°
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September, no crowd data, average high temperature 28 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
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21°
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October, no crowd data, average high temperature 21 degrees Celsius, average low temperature 11 degrees Celsius. Sunny most days.
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14°
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November, no crowd data, average high temperature 14 degrees Celsius, average low temperature 5 degrees Celsius. Partly sunny.
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9°
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December, no crowd data, average high temperature 9 degrees Celsius, average low temperature 2 degrees Celsius. Partly sunny.
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6°
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January, no crowd data, average high temperature 6 degrees Celsius, average low temperature -1 degrees Celsius. Partly sunny.
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8°
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February, no crowd data, average high temperature 8 degrees Celsius, average low temperature 0 degrees Celsius. Partly sunny.
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14°
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March, no crowd data, average high temperature 14 degrees Celsius, average low temperature 5 degrees Celsius. Partly sunny.
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20°
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April, no crowd data, average high temperature 20 degrees Celsius, average low temperature 10 degrees Celsius. Sunny most days.
10°
Monthly weather averages (˚C)

Top landmarks in Sikeston

Sikeston Depot Museum

3.8/5 (57 reviews)
The center of Sikeston is home to cultural attractions like Sikeston Depot Museum, so you might want to stop by during your stay. If you want to experience more of the culture Sikeston has to offer, head to Central Park and City of Miner Convention Center.
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Sikeston and related destinations

Catch a hot roll in mid-air at Lambert's Cafe, where servers hurl fresh bread across the dining room with remarkable accuracy. The historic downtown reveals a slice of small-town Americana, while the Sikeston Depot Museum chronicles the railroad heritage that put this place on the map. Central Park offers a leafy respite after exploring Front Street Studio & Art Gallery's local artwork. The City of Miner Convention Center hosts events that draw visitors from across the region. Positioned at the crossroads of major highways, this makes an ideal stopover between larger destinations, though locals insist you'll find reasons to linger beyond the flying carbs that made the town famous.

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Good Day Sunshine Early Morning Sunshine passes through the fog and scatters through the leaves of a tree in Scott County Missouri

Check out reviews of Sikeston hotels guests love

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau

10/10 Excellent
"breakfast fresh - did not use gym - staff very friendly"
Kim 1-night trip
Posted 1 hour ago
Fairfield Inn & Suites by Marriott Cape Girardeau

Frequently asked questions

What accommodations do travelers recommend in Sikeston?
Guests like Drury Inn & Suites Sikeston, MO, Hampton Inn Sikeston and Best Western Plus Sikeston I-55.
Can I book a refundable accommodation in Sikeston?
If you're looking for the flexibility to change your travel plans to Sikeston, most properties provide refundable* rates you can book. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in Sikeston if I want a cheap accommodation?
Two inexpensive options worth considering are Hampton Inn Sikeston and Best Western Plus Sikeston I-55.
What will the weather in Sikeston be like during my vacation?
The warmest months in Sikeston are usually July and August with an average temp of 77°F. January and February are the chilliest months when the average temp is 41°F. The rainiest months are April and March.
Why should I book my Sikeston hotel with Hotels.com?
There are plenty of reasons to book your Sikeston travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.