Hotels in Sikeston

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight
Aug 24 - Aug 25
Tomorrow
Aug 25 - Aug 26
This weekend
Aug 28 - Aug 30
Next weekend
Sep 4 - Sep 6

Where to stay in Sikeston?

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.
A hotel room with a patterned sofa, a yellow ottoman, a desk with a TV, and a framed picture on the wall.
A spacious lobby with a polished floor, seating areas, and modern lighting fixtures.
A spacious dining area with high tables and chairs, a bar counter, and large windows providing natural light.

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
Sikeston
$94
$108 total
includes taxes & fees
Aug 30 - Aug 31
Drury Inn & Suites Sikeston, MO
A Holiday Inn Express building with a covered entrance, stone pillars, and multiple windows.
An indoor swimming pool with clear water, a lifeguard chair, and a pool ladder.
A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.
A buffet with labeled food items and a patterned wall in the background.

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
Sikeston
$105
$119 total
includes taxes & fees
Aug 30 - Aug 31
Holiday Inn Express & Suites Sikeston Southwest by IHG
A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.
A conference room with a large rectangular table, six chairs with patterned upholstery, two modern ceiling lights, a bowl of fruit on the table, and large windows with curtains.
A hotel lobby with a bar area, seating arrangements, and a large window providing natural light.
A Hampton Inn hotel with a modern facade, a stone entrance, and a well-lit entrance area.

Hampton Inn Sikeston

Hampton Inn Sikeston
Sikeston
$102
$115 total
includes taxes & fees
Sep 20 - Sep 21
Hampton Inn Sikeston
A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.
An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and large windows providing natural light.
A reception area with a wooden reception desk, a large painting on the wall, and a potted plant.

Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
Sikeston
$89
$102 total
includes taxes & fees
Aug 30 - Aug 31
Best Western Plus Sikeston I-55
An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.
A modern indoor swimming pool with clear glass walls, a tiled deck, and multiple lounge chairs.
A modern hotel building with a sign reading "TOWNPLACE SUITES BY MARRIOTT" and "Fairfield BY MARRIOTT".
A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
Sikeston
$101
$114 total
includes taxes & fees
Sep 13 - Sep 14
Fairfield Inn & Suites by Marriott Sikeston
A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.
A spacious room with a large dining table and chairs, a kitchenette area, and a television mounted on the wall.
A Days Inn hotel with a brick facade, large windows, and a sign above the entrance.
A spacious lobby with a central atrium, a piano, and a reception desk.

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
Sikeston
$65
$75 total
includes taxes & fees
Aug 27 - Aug 28
Days Inn and Suites by Wyndham Sikeston
A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.
A Travel Inn and Suites building with a prominent illuminated sign, a brick facade, and a parking lot.
A modern kitchen with stainless steel appliances, wooden cabinets, and a bright yellow accent wall.
A reception area with a sign for 'Travel Inn and Suites'.

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Sikeston
$68
$78 total
includes taxes & fees
Aug 25 - Aug 26
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
A Comfort Inn & Suites hotel with a clear entrance, a covered parking area, and a sign indicating a 12' clearance.
A living room with two sofas, a coffee table, a TV, and a cabinet.
A hot tub area with a tiled floor, a wooden deck surrounding the tub, and a view of the sky through large windows.
A hotel room with a bed, a desk with a TV, a chair, a bathroom with a bathtub, and a window with curtains.

Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
Sikeston
$90
$103 total
includes taxes & fees
Sep 20 - Sep 21
Comfort Inn & Suites Sikeston I-55
A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.
A hotel kitchen with a long counter, various appliances, and a tiled backsplash.
A motel with a covered entrance, multiple rooms, and a parking lot.
A hotel room with two beds, a sofa, a coffee table, and artwork on the walls.

Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
Sikeston
$61
$70 total
includes taxes & fees
Aug 25 - Aug 26
Super 8 by Wyndham Sikeston/Miner Area
A modern hotel room with a large window, a gray sofa, a small round table, a white chair, and a bed.
A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.
A modern hotel with a sign reading "Towneplace Suites by Marriott Fairfield." It features a flat roof, large windows, and a well-lit entrance.

TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
Sikeston
$118
$134 total
includes taxes & fees
Sep 3 - Sep 4
TownePlace Suites by Marriott Sikeston
A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.
A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.
A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
$100
$113 total
includes taxes & fees
Aug 30 - Aug 31
Drury Plaza Hotel Cape Girardeau Conference Center
A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.
A hotel room with a bed, a desk, a chair, a kitchenette, and a bathroom.
A buffet with labeled containers of omelets and other dishes.
An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
$102
$115 total
includes taxes & fees
Sep 21 - Sep 22
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.
An indoor swimming pool with a wooden ceiling, lounge chairs, and a lifeguard chair.
A hotel room with two beds, a brick wall, and a wooden headboard.
A Drury Inn & Suites building with a traditional architectural style, featuring a covered entrance and multiple windows.

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
Jackson
$84
$89 total
includes taxes & fees
Aug 30 - Aug 31
Drury Inn & Suites Jackson MO
A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.
A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.
A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.
A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
Cape Girardeau
$72
$81 total
includes taxes & fees
Aug 30 - Aug 31
Pear Tree Inn Cape Girardeau West
A spacious dining area with high ceilings, large windows, and modern lighting fixtures.
A gym with exercise equipment, a treadmill, and a wall-mounted TV.
A large indoor swimming pool with clear blue water, surrounded by tiled flooring and blue walls.
An outdoor patio with stone walls, wicker furniture, and large windows.

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
Cape Girardeau
$106
$119 total
includes taxes & fees
Aug 30 - Aug 31
Hampton Inn Cape Girardeau I 55 East
A hotel room with two beds, a desk, a chair, a TV, and a mirror.
A reception area with a sofa, a small table, a trash bin, a microwave, and a book display.
A motel with a blue awning and a green 7-Eleven. It has a covered parking area and a two-story structure with a balcony.
A reception area with a counter, a coffee machine, and seating.

Country Yard Inn and Suite

Country Yard Inn and Suite
Sikeston
$59
$71 total
includes taxes & fees
Sep 16 - Sep 17
Country Yard Inn and Suite
A spacious lobby with a curved staircase, large windows, and a seating area with a rug.
A hotel room with two beds, a desk, a chair, and a view of the city.
A modern living room with a large sectional sofa, a flat-screen TV, and a view of the sea through large windows.
A modern outdoor seating area with a glass-top table and a fire feature, overlooking a sunset view.

The Riverview

The Riverview
Cape Girardeau
$114
$129 total
includes taxes & fees
Aug 25 - Aug 26
The Riverview
A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.
A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.
A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.
A hotel room with two beds, a nightstand, a lamp, and a chair.

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Jackson
$88
$96 total
includes taxes & fees
Aug 25 - Aug 26
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.
A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.
A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.
A reception area with a wooden reception desk, a glass door leading to a storage room, and a decorative wall piece.

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
Cape Girardeau
$101
$114 total
includes taxes & fees
Aug 30 - Aug 31
Fairfield Inn & Suites by Marriott Cape Girardeau
A spacious lobby with marble flooring, elegant seating, and a grand staircase.
A lobby with seating areas, a reception desk, and a bar.
A modern hotel lobby with a framed advertisement for breakfast at the new Bistro, a seating area with sofas and a coffee table, and a decorative mirror reflecting the space.
A Courtyard by Marriott hotel with a modern brick facade, large windows, and a covered entrance area.

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
Cape Girardeau
$125
$142 total
includes taxes & fees
Sep 4 - Sep 5
Courtyard by Marriott Cape Girardeau Downtown
View all properties

Check out pet-friendly hotels in Sikeston

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.
A hotel room with a patterned sofa, a yellow ottoman, a desk with a TV, and a framed picture on the wall.
A spacious lobby with a polished floor, seating areas, and modern lighting fixtures.
A spacious dining area with high tables and chairs, a bar counter, and large windows providing natural light.

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
Sikeston
$94
$108 total
includes taxes & fees
Aug 30 - Aug 31
Drury Inn & Suites Sikeston, MO
A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.
An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and large windows providing natural light.
A reception area with a wooden reception desk, a large painting on the wall, and a potted plant.

Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
Sikeston
$89
$102 total
includes taxes & fees
Aug 30 - Aug 31
Best Western Plus Sikeston I-55
A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.
A conference room with a large rectangular table, six chairs with patterned upholstery, two modern ceiling lights, a bowl of fruit on the table, and large windows with curtains.
A hotel lobby with a bar area, seating arrangements, and a large window providing natural light.
A Hampton Inn hotel with a modern facade, a stone entrance, and a well-lit entrance area.

Hampton Inn Sikeston

Hampton Inn Sikeston
Sikeston
$102
$115 total
includes taxes & fees
Sep 20 - Sep 21
Hampton Inn Sikeston
A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.
A Travel Inn and Suites building with a prominent illuminated sign, a brick facade, and a parking lot.
A modern kitchen with stainless steel appliances, wooden cabinets, and a bright yellow accent wall.
A reception area with a sign for 'Travel Inn and Suites'.

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Sikeston
$68
$78 total
includes taxes & fees
Aug 25 - Aug 26
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
A Comfort Inn & Suites hotel with a clear entrance, a covered parking area, and a sign indicating a 12' clearance.
A living room with two sofas, a coffee table, a TV, and a cabinet.
A hot tub area with a tiled floor, a wooden deck surrounding the tub, and a view of the sky through large windows.
A hotel room with a bed, a desk with a TV, a chair, a bathroom with a bathtub, and a window with curtains.

Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
Sikeston
$90
$103 total
includes taxes & fees
Sep 20 - Sep 21
Comfort Inn & Suites Sikeston I-55
A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.
A spacious room with a large dining table and chairs, a kitchenette area, and a television mounted on the wall.
A Days Inn hotel with a brick facade, large windows, and a sign above the entrance.
A spacious lobby with a central atrium, a piano, and a reception desk.

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
Sikeston
$65
$75 total
includes taxes & fees
Aug 27 - Aug 28
Days Inn and Suites by Wyndham Sikeston
A modern hotel room with a large window, a gray sofa, a small round table, a white chair, and a bed.
A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.
A modern hotel with a sign reading "Towneplace Suites by Marriott Fairfield." It features a flat roof, large windows, and a well-lit entrance.

TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
Sikeston
$118
$134 total
includes taxes & fees
Sep 3 - Sep 4
TownePlace Suites by Marriott Sikeston
A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.
A hotel kitchen with a long counter, various appliances, and a tiled backsplash.
A motel with a covered entrance, multiple rooms, and a parking lot.
A hotel room with two beds, a sofa, a coffee table, and artwork on the walls.

Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
Sikeston
$61
$70 total
includes taxes & fees
Aug 25 - Aug 26
Super 8 by Wyndham Sikeston/Miner Area
A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.
A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.
A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
$100
$113 total
includes taxes & fees
Aug 30 - Aug 31
Drury Plaza Hotel Cape Girardeau Conference Center
A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.
A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.
A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.
A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
Cape Girardeau
$72
$81 total
includes taxes & fees
Aug 30 - Aug 31
Pear Tree Inn Cape Girardeau West
View all properties

You may also like hotels with pools in Sikeston

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.
A hotel room with a patterned sofa, a yellow ottoman, a desk with a TV, and a framed picture on the wall.
A spacious lobby with a polished floor, seating areas, and modern lighting fixtures.
A spacious dining area with high tables and chairs, a bar counter, and large windows providing natural light.

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
Sikeston
$94
$108 total
includes taxes & fees
Aug 30 - Aug 31
Drury Inn & Suites Sikeston, MO
A Holiday Inn Express building with a covered entrance, stone pillars, and multiple windows.
An indoor swimming pool with clear water, a lifeguard chair, and a pool ladder.
A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.
A buffet with labeled food items and a patterned wall in the background.

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
Sikeston
$105
$119 total
includes taxes & fees
Aug 30 - Aug 31
Holiday Inn Express & Suites Sikeston Southwest by IHG
An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.
A modern indoor swimming pool with clear glass walls, a tiled deck, and multiple lounge chairs.
A modern hotel building with a sign reading "TOWNPLACE SUITES BY MARRIOTT" and "Fairfield BY MARRIOTT".
A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
Sikeston
$101
$114 total
includes taxes & fees
Sep 13 - Sep 14
Fairfield Inn & Suites by Marriott Sikeston
A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.
An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and large windows providing natural light.
A reception area with a wooden reception desk, a large painting on the wall, and a potted plant.

Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
Sikeston
$89
$102 total
includes taxes & fees
Aug 30 - Aug 31
Best Western Plus Sikeston I-55
A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.
A conference room with a large rectangular table, six chairs with patterned upholstery, two modern ceiling lights, a bowl of fruit on the table, and large windows with curtains.
A hotel lobby with a bar area, seating arrangements, and a large window providing natural light.
A Hampton Inn hotel with a modern facade, a stone entrance, and a well-lit entrance area.

Hampton Inn Sikeston

Hampton Inn Sikeston
Sikeston
$102
$115 total
includes taxes & fees
Sep 20 - Sep 21
Hampton Inn Sikeston
A modern hotel room with a large window, a gray sofa, a small round table, a white chair, and a bed.
A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.
A modern hotel with a sign reading "Towneplace Suites by Marriott Fairfield." It features a flat roof, large windows, and a well-lit entrance.

TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
Sikeston
$118
$134 total
includes taxes & fees
Sep 3 - Sep 4
TownePlace Suites by Marriott Sikeston
A Comfort Inn & Suites hotel with a clear entrance, a covered parking area, and a sign indicating a 12' clearance.
A living room with two sofas, a coffee table, a TV, and a cabinet.
A hot tub area with a tiled floor, a wooden deck surrounding the tub, and a view of the sky through large windows.
A hotel room with a bed, a desk with a TV, a chair, a bathroom with a bathtub, and a window with curtains.

Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
Sikeston
$90
$103 total
includes taxes & fees
Sep 20 - Sep 21
Comfort Inn & Suites Sikeston I-55
A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.
A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.
A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
$100
$113 total
includes taxes & fees
Aug 30 - Aug 31
Drury Plaza Hotel Cape Girardeau Conference Center
A modern retail area with a display of local items and snacks.
An outdoor patio area with seating arrangements, including a sofa and chairs, and a table.
A modern indoor seating area with blue sofas and tables, a patterned carpet, and large windows offering a view of the outdoors.
A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
Cape Girardeau
$89
$102 total
includes taxes & fees
Aug 30 - Aug 31
Tru By Hilton Cape Girardeau
A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.
An indoor swimming pool with a wooden ceiling, lounge chairs, and a lifeguard chair.
A hotel room with two beds, a brick wall, and a wooden headboard.
A Drury Inn & Suites building with a traditional architectural style, featuring a covered entrance and multiple windows.

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
Jackson
$84
$89 total
includes taxes & fees
Aug 30 - Aug 31
Drury Inn & Suites Jackson MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Our prices for hotels in Sikeston are cheapest in November
Price trends for hotels in Sikeston
Pricing is based on two traveler single night rates
View properties in August
Typical weather for Sikeston
August
High 31°C / low 21°C. Sunny most days.
View properties in August
31°
21°
28°
17°
21°
11°
14°
5°
9°
2°
6°
-1°
8°
0°
14°
5°
20°
10°
25°
16°
30°
20°
32°
22°
Monthly weather averages (˚C)

Top landmarks in Sikeston

Sikeston Depot Museum

7.6/10 (57 reviews)
The center of Sikeston is home to cultural attractions like Sikeston Depot Museum, so you might want to stop by during your stay. If you want to experience more of the culture Sikeston has to offer, head to City of Miner Convention Center and Central Park.
See properties

Central Park

7.2/10 (56 reviews)
Central Park is 0.5 mi (0.8 km) from central Sikeston, why not stop by during your stay.
See properties

City of Miner Convention Center

City of Miner Convention Center is worth a visit when in central Miner.
See properties

Sikeston and related destinations

Catch a hot roll in mid-air at Lambert's Cafe, where servers hurl fresh bread across the dining room with remarkable accuracy. The historic downtown reveals a slice of small-town Americana, while the Sikeston Depot Museum chronicles the railroad heritage that put this place on the map. Central Park offers a leafy respite after exploring Front Street Studio & Art Gallery's local artwork. The City of Miner Convention Center hosts events that draw visitors from across the region. Positioned at the crossroads of major highways, this makes an ideal stopover between larger destinations, though locals insist you'll find reasons to linger beyond the flying carbs that made the town famous.

See all hotels in Sikeston
A tree with sunlight filtering through its leaves, creating a warm glow.

Check out reviews of Sikeston hotels guests love

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

10/10 Excellent
"The room was clean and quiet. Staff was friendly and professional and helpful. Breakfast was very good with plenty of options. Second time I have stayed here and felt safe as a woman traveling with her daughter. Only minor complaint is that the pillows aren't the best. Recommend bringing your own from home if you can."
Jacqueline 1-night trip
Posted 4 hours ago
Pear Tree Inn Cape Girardeau West
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent
"Clean rooms, friendly staff, I would definitely stay here again next time I’m in town."
Matthew 1-night trip
Posted 5 hours ago
Drury Plaza Hotel Cape Girardeau Conference Center
Hampton Inn Sikeston

Hampton Inn Sikeston

10/10 Excellent
"👍"
Gregory S 1-night trip
Posted 17 hours ago
Hampton Inn Sikeston
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

10/10 Excellent
"Very clean and friendly staff"
Angela 2-night trip
Posted 20 hours ago
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55

10/10 Excellent
"I really loved everything about my stay and the hotel in general. Nice Job"
Jimmy 2-night trip
Posted 21 hours ago
Best Western Plus Sikeston I-55
The Riverview

The Riverview

8/10 Good
"Nice view of the river. The staff was nice."
Pamela 1-night trip
Posted 1 day ago
The Riverview
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

10/10 Excellent
"Great value, very clean and breakfast was actually good."
Ken 1-night trip
Posted 2 days ago
Drury Inn & Suites Sikeston, MO
Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

10/10 Excellent
"Good price."
Kevin 1-night trip
Posted 2 days ago
Super 8 by Wyndham Sikeston/Miner Area
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

10/10 Excellent
"We stay here every time we are in Sikesons. Can't beat this hotel. Super clean 'comfortable!' beds, living room area, and bathrooms. Small hot breakfast. All for the best price out there. Don't skip on this hotel! Staff is always polite and helpful. We always love to walk out to the pond"
Cheyenna 1-night trip
Posted 4 days ago
Days Inn and Suites by Wyndham Sikeston

Frequently asked questions

What accommodations do travelers recommend in Sikeston?
Guests like Drury Inn & Suites Sikeston, MO, Days Inn and Suites by Wyndham Sikeston and Best Western Plus Sikeston I-55.
Can I book a refundable accommodation in Sikeston?
If you're looking for the flexibility to change your travel plans to Sikeston, most properties provide refundable* rates you can book. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in Sikeston if I want a cheap accommodation?
Days Inn and Suites by Wyndham Sikeston, Holiday Inn Express & Suites Sikeston Southwest by IHG and Best Western Plus Sikeston I-55 are a few accommodations you might want to consider that'll save you money.
What will the weather in Sikeston be like during my vacation?
The warmest months in Sikeston are usually July and August with an average temp of 77°F. January and February are the chilliest months when the average temp is 41°F. The rainiest months are April and March.
Why should I book my Sikeston hotel with Hotels.com?
There are plenty of reasons to book your Sikeston travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Keep exploring