Hotels in Santiago Sur

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Cabaña Chepo HERRERA
Cabaña Chepo HERRERA
2.0 star property
Chepo
The price is $85
$94 total
includes taxes & fees
Feb 24 - Feb 25
Cabaña Chepo HERRERA
Camino del Sol
Camino del Sol
3.5 star property
Torio
9.4 out of 10, Exceptional, (14 reviews)
The price is $170
$187 total
includes taxes & fees
Mar 2 - Mar 3
Camino del Sol
Hotel Mykonos Panama
Hotel Mykonos Panama
3.5 star property
Nuevo Santiago
8.8 out of 10, Excellent, (550 reviews)
Escape to this hotel in Nuevo Santiago with 3 outdoor pools, poolside bar, and rejuvenating spa treatments. Enjoy free breakfast and WiFi while staying near Plaza Banconal. After a massage or facial, grab a bite at the café.
The price is $90
$99 total
includes taxes & fees
Feb 24 - Feb 25
Hotel Mykonos Panama
Casa Morrillo
Casa Morrillo
3.0 star property
Torio
10.0 out of 10, Exceptional, (1 review)
Situated on the bay in Torio, this beachside haven offers easy access to Morrillo Beach and Duarte Point. After enjoying the complimentary breakfast, unwind at the coffee shop or sip drinks at the bar. The garden and terrace complete your coastal escape.
The price is $68
$75 total
includes taxes & fees
Feb 24 - Feb 25
Casa Morrillo
Punta Duarte Garden Inn
Punta Duarte Garden Inn
3.0 star property
Torio
9.2 out of 10, Wonderful, (37 reviews)
Waves crash steps from this beachfront lodge with an outdoor pool and hot tub. Enjoy meals at The View restaurant while gazing at the ocean. Surf at Duarte Point or explore Morrillo Beach, then relax in the garden after your adventures.
The price is $119
$131 total
includes taxes & fees
Feb 27 - Feb 28
Punta Duarte Garden Inn
Hotel Galería
Hotel Galería
3.0 star property
Nuevo Santiago
8.4 out of 10, Very Good, (208 reviews)
Immerse in Nuevo Santiago's energy at this welcoming hotel offering 2 outdoor pools, including one for children. Grab meals at Restaurante Galería or unwind at the bar/lounge after exploring nearby Plaza Banconal and Omar Torrijos Herrera Stadium.
The price is $69
$76 total
includes taxes & fees
Feb 26 - Feb 27
Hotel Galería
Hotel Gran David
Hotel Gran David
3.5 star property
Santiago
8.6 out of 10, Excellent, (375 reviews)
Unwind at this Santiago hotel with its inviting outdoor pool and poolside bar. Just minutes from Plaza Banconal and Omar Torrijos Herrera Stadium, enjoy complimentary breakfast, WiFi and parking. The 24-hour health club and helpful staff ensure a comfortable business or leisure stay.
Hotel Gran David
Hotel Playa Reina
Hotel Playa Reina
3.0 star property
Mariato
7.8 out of 10, Good, (25 reviews)
Wake to Pacific waves at this coastal hotel offering complimentary kayaking adventures and bike rentals for shoreline exploration. Enjoy fresh seafood at Alamar restaurant after cooling off in the outdoor pool, then unwind with beachside massages as sunset paints the Mariato horizon.
Hotel Playa Reina
Hotel Hibiscus Garden / Jardin De Papos
Hotel Hibiscus Garden / Jardin De Papos
2.5 star property
Hicaco
6.4 out of 10, (14 reviews)
Escape to this oceanfront haven in Panama with direct beach access and an outdoor pool for sunset swims. Kokodrilo Bar & Grill serves international cuisine all day, while the poolside bar and garden offer perfect relaxation spots near Lagartero Beach.
The price is $48
$52 total
includes taxes & fees
Mar 2 - Mar 3
Hotel Hibiscus Garden / Jardin De Papos
Kooteja Santa Catalina KAÏSA
Kooteja Santa Catalina KAÏSA
3.0 star property
Hicaco
7.4 out of 10, Good, (3 reviews)
The price is $62
$98 total
includes taxes & fees
Feb 24 - Feb 25
Kooteja Santa Catalina KAÏSA
Hotel y Restaurante Mama Ines
Hotel y Restaurante Mama Ines
3.0 star property
Hicaco
8.6 out of 10, Excellent, (28 reviews)
Immerse in paradise at this beachside hotel with an outdoor pool, bar, and cafe. Just moments from Estero and Arrimadero beaches, enjoy complimentary breakfast, WiFi and parking. The garden and terrace create a relaxing tropical atmosphere.
The price is $71
$78 total
includes taxes & fees
Feb 25 - Feb 26
Hotel y Restaurante Mama Ines
SurfAsana Lodge
SurfAsana Lodge
2.0 star property
Santa Catalina
10.0 out of 10, Exceptional, (3 reviews)
The price is $91
$100 total
includes taxes & fees
Feb 24 - Feb 25
SurfAsana Lodge
Bambuda Santa Catalina
Bambuda Santa Catalina
2.5 star property
Hicaco
9.2 out of 10, Wonderful, (61 reviews)
Soak in tropical vibes at this inviting hostal, where an outdoor pool refreshes after beach adventures. Just minutes from stunning local beaches, with convenient amenities like free WiFi, parking, and an on-site café and bar for relaxed island living.
The price is $73
$80 total
includes taxes & fees
Mar 23 - Mar 24
Bambuda Santa Catalina
zenda house
zenda house
3.5 star property
Hicaco
4.0 out of 10, (1 review)
The price is $65
$119 total
includes taxes & fees
Mar 19 - Mar 20
zenda house
Hotel Santa Catalina Panama
Hotel Santa Catalina Panama
3.0 star property
Hicaco
9.0 out of 10, Wonderful, (132 reviews)
This colonial inn sits by the ocean, featuring an inviting outdoor pool and poolside bar. Enjoy regional cuisine at Pescao restaurant while exploring nearby Estero and Arrimadero beaches. Free WiFi and parking enhance your coastal escape.
Hotel Santa Catalina Panama
Villa Coco
Villa Coco
2.5 star property
Hicaco
9.2 out of 10, Wonderful, (49 reviews)
Experience the tropical magic of this family-friendly hotel with outdoor and children's pools near Estero Beach. Relax with massage services or enjoy refreshments at the poolside bar after exploring Arrimadero Beach nearby.
The price is $165
$182 total
includes taxes & fees
Mar 11 - Mar 12
Villa Coco
Nukumi Club
Nukumi Club
4.0 star property
Santa Catalina
10.0 out of 10, Exceptional, (1 review)
The price is $175
$193 total
includes taxes & fees
Feb 25 - Feb 26
Nukumi Club
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

What hotels do travelers like in Santiago Sur?
Guests like Cabañas Palma Real.
Can I book a refundable hotel in Santiago Sur?
If you want the flexibility to change your travel plans to Santiago Sur, most accommodations provide refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.
What will the weather in Santiago Sur be like during my trip?
Santiago Sur is a great place to visit any time of year with an average temperature of 77°F during the coldest months.
Why should I book my Santiago Sur accommodation with Hotels.com?
There are plenty of reasons to book your Santiago Sur travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.