Hotels in Santa Cruz

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Tonight
Dec 5 - Dec 6
Tomorrow
Dec 6 - Dec 7
This weekend
Dec 5 - Dec 7
Next weekend
Dec 12 - Dec 14

Where to stay in Santa Cruz?

Living area
Posada Express Fast Check
Posada Express Fast Check
3.0 star property
10.0 out of 10, Exceptional, (2)
The price is $50
$55 total
Jan 1 - Jan 2, 2026
Posada Express Fast Check
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Great weekend hotel deals in Santa Cruz

Showing deals for:Dec 12 - Dec 14

Image gallery for Novotel Santa Cruz De La Sierra

Exterior
VIP Access

Novotel Santa Cruz De La Sierra

5.0 star property
Santa Cruz
9.2/10Wonderful (103 reviews)
Member Price available
$120 nightly
Price is $240
Novotel Santa Cruz De La Sierra

Check out family-friendly hotels in Santa Cruz

Lounge
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (253)
The price is $64
$64 total
Dec 11 - Dec 12
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
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You may also like hotels with spas in Santa Cruz

2 outdoor pools
Prince Hotel

Prince Hotel

3.0 star property
Santa Cruz
The price is $54
$56 total
Dec 6 - Dec 7
Prince Hotel
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You can also stay at hotels with a hot tub in Santa Cruz

Seasonal outdoor pool
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (345)
The price is $134
$134 total
Dec 11 - Dec 12
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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When is the best time to visit Santa Cruz?

Our prices for hotels in Santa Cruz are cheapest in February
Price trends for hotels in Santa Cruz
Pricing is based on two traveler single night rates
View properties in December
Currently viewing crowd sizes and weather for December.
Typical weather for Santa Cruz
December
Low crowds
High 31°C / low 22°C. Sunny most days.
View properties in December
31°
weather_sun
December, Low crowds, average high temperature 31 degrees Celsius, average low temperature 22 degrees Celsius. Sunny most days.
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31°
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January, Moderate crowds, average high temperature 31 degrees Celsius, average low temperature 22 degrees Celsius. Sunny most days.
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29°
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February, High crowds, average high temperature 29 degrees Celsius, average low temperature 22 degrees Celsius. Cloudy most days.
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29°
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March, High crowds, average high temperature 29 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
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28°
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April, Moderate crowds, average high temperature 28 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
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25°
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May, Low crowds, average high temperature 25 degrees Celsius, average low temperature 18 degrees Celsius. Sunny most days.
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24°
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June, Moderate crowds, average high temperature 24 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
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25°
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July, Moderate crowds, average high temperature 25 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
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28°
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August, Low crowds, average high temperature 28 degrees Celsius, average low temperature 18 degrees Celsius. Sunny most days.
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31°
weather_sun
September, High crowds, average high temperature 31 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
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32°
weather_sun
October, High crowds, average high temperature 32 degrees Celsius, average low temperature 22 degrees Celsius. Sunny most days.
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32°
weather_sun
November, Low crowds, average high temperature 32 degrees Celsius, average low temperature 22 degrees Celsius. Sunny most days.
22°
Monthly weather averages (˚C)

Top neighborhoods in Santa Cruz

Top landmarks in Santa Cruz

Plaza 24 de Septiembre showing street scenes

Plaza 24 de Septiembre

4.4/5 (70 reviews)
If you're planning a bit of sightseeing during your trip, head to Plaza 24 de Septiembre— just one of the monuments in central Santa Cruz.
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San Lorenzo Cathedral showing a church or cathedral and interior views

San Lorenzo Cathedral

4.5/5 (36 reviews)
San Lorenzo Cathedral is in the heart of Santa Cruz, so why not stop by during your stay.
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Learn more about Santa Cruz

Santa Cruz is applauded for its cultural attractions such as Ethno-folkloric Museum and Cine Center.

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San Lorenzo Cathedral showing a garden

Check out reviews of Santa Cruz hotels guests love

HOTEL OSHO

HOTEL OSHO

10/10 Excellent
"Excellent"
Neysa 4-night trip
Posted 4 days ago
HOTEL OSHO

Frequently asked questions

What hotels do travelers recommend in Santa Cruz?
Ibis Santa Cruz DE LA Sierra, Chairú Eco Hotel and Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel are all accommodations that are popular with guests.
Where can I find free parking at my hotel in Santa Cruz?
These hotels offer the perk of free parking: Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel, Hotel LP Equipetrol and Hotel LP Santa Cruz Centro. There are 8 options you may want to check out on our site.
Can I book refundable hotels in Santa Cruz?
If you want the flexibility to change your plans to Santa Cruz, most accommodations offer refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.
Where can I stay in Santa Cruz if I want a vacation rental instead of a hotel?
If you want to find a good alternative to a hotel, browse our selection of 24 vacation homes. In addition, you can choose from 182 apartments.
What will the weather in Santa Cruz be like during my trip?
Santa Cruz is a great place to visit to enjoy the sunshine any time of year with an average temp of 70°F.
Why should I book my Santa Cruz accommodation with Hotels.com?
There are lots of reasons to book your Santa Cruz trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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