Hotels in Saint Matthews

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Check prices for these dates

Tonight
Feb 28 - Mar 1
Tomorrow
Mar 1 - Mar 2
Next weekend
Mar 6 - Mar 8
In two weeks
Mar 13 - Mar 15

Where to stay in Saint Matthews?

Free daily buffet breakfast
Tru By Hilton Santee
Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (740 reviews)
  • cleanliness
    Experience a comfortable stay near Santee Cooper Country Club with top-rated service.
The price is $109
$121 total
includes taxes & fees
Mar 9 - Mar 10
Tru By Hilton Santee
Room, 2 Queen Beds, Kitchenette | Desk, free rollaway beds, free WiFi, bed sheets
Crown Inn By Oyo Orangeburg Hwy 301
Crown Inn By Oyo Orangeburg Hwy 301
2.5 star property
Orangeburg
3.0 out of 10, (7 reviews)
  • cleanliness
    Highway 301 retreat with comfortable rooms and free parking in Orangeburg.
The price is $50
$58 total
includes taxes & fees
Mar 1 - Mar 2
Crown Inn By Oyo Orangeburg Hwy 301
Lobby lounge
Fairfield Inn by Marriott Orangeburg
Fairfield Inn by Marriott Orangeburg
3.0 star property
Orangeburg
8.4 out of 10, Very Good, (728 reviews)
  • cleanliness
    Swim into comfort at this Orangeburg hotel with fitness options and seasonal pool.
The price is $84
$93 total
includes taxes & fees
Mar 29 - Mar 30
Fairfield Inn by Marriott Orangeburg
Property amenity
Fairfield Inn & Suites by Marriott Santee
Fairfield Inn & Suites by Marriott Santee
3.0 star property
Santee
9.8 out of 10, Exceptional, (1,005 reviews)
  • cleanliness
    Comfortable hotel in a tranquil setting, perfect for morning swims and golf outings.
The price is $125
$139 total
includes taxes & fees
Mar 8 - Mar 9
Fairfield Inn & Suites by Marriott Santee
Comfort Single Room | Desk, free WiFi
Orangeburg Inn & Suites
Orangeburg Inn & Suites
2.0 star property
Orangeburg
6.0 out of 10, (60 reviews)
  • cleanliness
    Enjoy comfort and easy access to Orangeburg's local attractions at this welcoming inn.
The price is $54
$61 total
includes taxes & fees
Mar 1 - Mar 2
Orangeburg Inn & Suites
Desk, blackout drapes, iron/ironing board, free WiFi
Baymont by Wyndham Santee
Baymont by Wyndham Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1,427 reviews)
  • cleanliness
    Relax in peaceful Santee with continental breakfast and helpful staff nearby.
The price is $80
$89 total
includes taxes & fees
Mar 1 - Mar 2
Baymont by Wyndham Santee
Room, 2 Queen Beds, Accessible, Non Smoking (Efficiency) | Desk, iron/ironing board, free cribs/infant beds, free WiFi
Comfort Inn & Suites Orangeburg
Comfort Inn & Suites Orangeburg
2.5 star property
Orangeburg
8.0 out of 10, Very Good, (581 reviews)
  • cleanliness
    Comfort and convenience minutes away from Smith-Hammond-Middleton Memorial Center.
The price is $106
$118 total
includes taxes & fees
Mar 8 - Mar 9
Comfort Inn & Suites Orangeburg
Breakfast area
Travelodge by Wyndham Orangeburg
Travelodge by Wyndham Orangeburg
2.0 star property
Orangeburg
8.2 out of 10, Very Good, (1,001 reviews)
  • cleanliness
    Modern Orangeburg stay with free WiFi and parking, near local attractions.
The price is $75
$83 total
includes taxes & fees
Mar 1 - Mar 2
Travelodge by Wyndham Orangeburg
Breakfast and dinner served
Courtyard by Marriott Columbia Cayce
Courtyard by Marriott Columbia Cayce
3.0 star property
Cayce
9.0 out of 10, Wonderful, (678 reviews)
  • cleanliness
    Wake up to Cayce's charm with refreshing dips in the outdoor pool.
The price is $118
$131 total
includes taxes & fees
Mar 8 - Mar 9
Courtyard by Marriott Columbia Cayce
Exterior
Best Western Plus Santee Inn
Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1,003 reviews)
The price is $112
$124 total
includes taxes & fees
Mar 1 - Mar 2
Best Western Plus Santee Inn
Desk, blackout drapes, iron/ironing board, free WiFi
Econo Lodge Inn & Suites Cayce I-26 Airport
Econo Lodge Inn & Suites Cayce I-26 Airport
2.0 star property
Cayce
6.8 out of 10, (23 reviews)
The price is $62
$69 total
includes taxes & fees
Mar 29 - Mar 30
Econo Lodge Inn & Suites Cayce I-26 Airport
Suite, 1 King Bed, Accessible, Smoking | Desk, blackout drapes, iron/ironing board, free WiFi
Quality Inn & Suites Orangeburg
Quality Inn & Suites Orangeburg
2.5 star property
Orangeburg
6.2 out of 10, (640 reviews)
  • cleanliness
    Affordable Orangeburg hotel with free amenities near dining and attractions.
The price is $63
$70 total
includes taxes & fees
Mar 8 - Mar 9
Quality Inn & Suites Orangeburg
Exterior
Holiday Inn Express & Suites Orangeburg by IHG
Holiday Inn Express & Suites Orangeburg by IHG
2.5 star property
Orangeburg
8.6 out of 10, Excellent, (810 reviews)
  • cleanliness
    Stay steps from Columbia and enjoy free perks at this convenient Orangeburg hotel.
The price is $134
$149 total
includes taxes & fees
Mar 9 - Mar 10
Holiday Inn Express & Suites Orangeburg by IHG
Seasonal outdoor pool
Spark by Hilton Orangeburg
Spark by Hilton Orangeburg
2.5 star property
Orangeburg
7.8 out of 10, Good, (1,003 reviews)
  • cleanliness
    Central stay in Orangeburg with seasonal pool and complimentary breakfast.
The price is $99
$110 total
includes taxes & fees
Mar 2 - Mar 3
Spark by Hilton Orangeburg
Property amenity
SpringHill Suites by Marriott Orangeburg
SpringHill Suites by Marriott Orangeburg
2.5 star property
Orangeburg
8.8 out of 10, Excellent, (703 reviews)
  • cleanliness
    Relax by the indoor pool near I.P. Stanback Museum in this convenient Orangeburg stay.
The price is $129
$143 total
includes taxes & fees
Mar 1 - Mar 2
SpringHill Suites by Marriott Orangeburg
Lobby
Sleep Inn Orangeburg
Sleep Inn Orangeburg
2.5 star property
Orangeburg
7.8 out of 10, Good, (399 reviews)
  • cleanliness
    Comfortable hotel with a seasonal pool and convenient perks in Orangeburg.
The price is $70
$78 total
includes taxes & fees
Mar 29 - Mar 30
Sleep Inn Orangeburg
Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes
Comfort Inn & Suites Santee
Comfort Inn & Suites Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1,000 reviews)
  • cleanliness
    Relax in a serene hotel with a seasonal outdoor pool near Santee attractions.
The price is $104
$115 total
includes taxes & fees
Mar 8 - Mar 9
Comfort Inn & Suites Santee
Desk, iron/ironing board, free WiFi, bed sheets
Baymont by Wyndham Orangeburg North
Baymont by Wyndham Orangeburg North
2.5 star property
Orangeburg
6.0 out of 10, (1,000 reviews)
  • cleanliness
    Perfect spot in Orangeburg with seasonal pool, free breakfast, and parking.
The price is $60
$66 total
includes taxes & fees
Mar 8 - Mar 9
Baymont by Wyndham Orangeburg North
Free WiFi
Suburban Studios Orangeburg
Suburban Studios Orangeburg
2.0 star property
Orangeburg
6.6 out of 10, (17 reviews)
  • cleanliness
    Visit Orangeburg for spacious comfort and convenient travel arrangements.
The price is $53
$59 total
includes taxes & fees
Mar 29 - Mar 30
Suburban Studios Orangeburg
Free daily full breakfast
Quality Inn & Suites Santee I-95
Quality Inn & Suites Santee I-95
2.5 star property
Santee
6.0 out of 10, (477 reviews)
  • cleanliness
    Experience the gateway to Santee's acclaimed golf clubs with complimentary perks.
The price is $54
$66 total
includes taxes & fees
Mar 8 - Mar 9
Quality Inn & Suites Santee I-95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Saint Matthews

The region around Saint Matthews is home to attractions such as Congaree National Park and Harry Hampton Visitor Center.

See all hotels in Saint Matthews
Moss Covered Cypress Trees Stand Tall in A Dark Marsh Of Congaree

Check out reviews of Saint Matthews hotels guests love

Tru By Hilton Columbia Downtown

Tru By Hilton Columbia Downtown

10/10 Excellent
"In one word the stay was outstanding! Customer service , professionalism, location, all of the above. Enjoyed our stay!"
Charles 1-night trip
Posted 11 hours ago
Tru By Hilton Columbia Downtown

Frequently asked questions

What hotels do travelers like in Saint Matthews?
Guests like Tru by Hilton Orangeburg.
Can I book a refundable hotel in Saint Matthews?
If you want the flexibility to change your travel plans to Saint Matthews, most hotels offer refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in Saint Matthews be like during my trip?
July and August are typically the warmest months in Saint Matthews when the average temp is 79°F. January and February are the coldest months when the average temperature is 51°F. August and July are the months with the most rain.
Why should I book my Saint Matthews accommodation with Hotels.com?
There are lots of reasons to book your Saint Matthews trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.