Photo by Caroline Nunez
Hotels in Mayesville
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Hampton Inn Sumter
Hampton Inn Sumter
2.5 star property
Sumter
8.6 out of 10, Excellent, (489)
8.6/10
Excellent
(489)
The price is $89
$89
$103 total
includes taxes & fees
Jan 4 - Jan 5, 2026
1912 Bed and Breakfast
1912 Bed and Breakfast
3.5 star property
Sumter
10.0 out of 10, Exceptional, (284)
10/10
Exceptional
(284)
The price is $117
$117
$132 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Holiday Inn Express Sumter by IHG
Holiday Inn Express Sumter by IHG
2.5 star property
Sumter
8.8 out of 10, Excellent, (701)
8.8/10
Excellent
(701)
The price is $107
$107
$120 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Hyatt Place Sumter / Downtown
Hyatt Place Sumter / Downtown
3.0 star property
Sumter
9.2 out of 10, Wonderful, (881)
9.2/10
Wonderful
(881)
The price is $115
$115
$129 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Tru by Hilton Sumter
Tru by Hilton Sumter
2.5 star property
Sumter
8.8 out of 10, Excellent, (671)
8.8/10
Excellent
(671)
The price is $85
$85
$96 total
includes taxes & fees
Jan 4 - Jan 5, 2026
SureStay Hotel by Best Western Manning
SureStay Hotel by Best Western Manning
2.5 star property
Manning
8.6 out of 10, Excellent, (1002)
8.6/10
Excellent
(1002)
The price is $89
$89
$99 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Woodspring Suites Sumter Near Shaw Afb
Woodspring Suites Sumter Near Shaw Afb
2.5 star property
Sumter
8.2 out of 10, Very Good, (142)
8.2/10
Very Good
(142)
The price is $104
$104
$116 total
includes taxes & fees
Dec 28 - Dec 29
Super 8 by Wyndham Sumter
Super 8 by Wyndham Sumter
2.0 star property
Sumter
7.2 out of 10, Good, (407)
7.2/10
Good
(407)
The price is $70
$70
$78 total
includes taxes & fees
Jan 4 - Jan 5, 2026
American Inn
American Inn
2.5 star property
Sumter
3.4 out of 10, (30)
3.4/10
(30)
The price is $60
$60
$67 total
includes taxes & fees
Dec 28 - Dec 29
Baymont by Wyndham Manning
Baymont by Wyndham Manning
2.5 star property
Manning
6.8 out of 10, (1000)
6.8/10
(1000)
The price is $80
$80
$89 total
includes taxes & fees
Dec 28 - Dec 29
Hampton Inn Manning
Hampton Inn Manning
2.5 star property
Manning
8.4 out of 10, Very Good, (1001)
8.4/10
Very Good
(1001)
The price is $119
$119
$132 total
includes taxes & fees
Jan 5 - Jan 6, 2026
SpringHill Suites Sumter
SpringHill Suites Sumter
2.5 star property
Sumter
9.4 out of 10, Exceptional, (452)
9.4/10
Exceptional
(452)
The price is $125
$125
$140 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Americas Best Value Inn Bishopville
Americas Best Value Inn Bishopville
2.0 star property
Bishopville
7.2 out of 10, Good, (90)
7.2/10
Good
(90)
The price is $85
$85
$95 total
includes taxes & fees
Dec 28 - Dec 29
Comfort Suites Sumter near Shaw AFB
Comfort Suites Sumter near Shaw AFB
2.5 star property
Sumter
7.2 out of 10, Good, (601)
7.2/10
Good
(601)
The price is $97
$97
$108 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Spark by Hilton Sumter
Spark by Hilton Sumter
2.5 star property
Sumter
7.6 out of 10, Good, (15)
7.6/10
Good
(15)
The price is $114
$114
$128 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Budget Inn Timmonsville
Budget Inn Timmonsville
2.0 star property
Timmonsville
7.0 out of 10, Good, (321)
7.0/10
Good
(321)
The price is $61
$61
$68 total
includes taxes & fees
Dec 28 - Dec 29
Red Roof Inn Bishopville
Red Roof Inn Bishopville
2.0 star property
Bishopville
6.2 out of 10, (139)
6.2/10
(139)
The price is $75
$75
$84 total
includes taxes & fees
Dec 28 - Dec 29
Super 8 by Wyndham Manning
Super 8 by Wyndham Manning
2.0 star property
Manning
6.4 out of 10, (374)
6.4/10
(374)
The price is $60
$60
$66 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Candlewood Suites Sumter by IHG
Candlewood Suites Sumter by IHG
2.5 star property
Sumter
8.4 out of 10, Very Good, (163)
8.4/10
Very Good
(163)
The price is $134
$134
$150 total
includes taxes & fees
Dec 28 - Dec 29
Affordable Suites Sumter SC
Affordable Suites Sumter SC
2.5 star property
Sumter
8.8 out of 10, Excellent, (37)
8.8/10
Excellent
(37)
The price is $78
$78
$88 total
includes taxes & fees
Jan 20 - Jan 21, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Budget hotels in Mayesville and vicinity
7.0 out of 10, Good, (321)
7.0/10
Good
(321)
The price is $61
$61
$68 total
includes taxes & fees
Dec 28 - Dec 29
8.0 out of 10, Very Good, (9)
8.0/10
Very Good
(9)
The price is $73
$73
$81 total
includes taxes & fees
Jan 11 - Jan 12, 2026
7.0 out of 10, Good, (7)
7.0/10
Good
(7)
The price is $68
$68
$76 total
includes taxes & fees
Dec 28 - Dec 29
7.2 out of 10, Good, (407)
7.2/10
Good
(407)
The price is $70
$70
$78 total
includes taxes & fees
Jan 4 - Jan 5, 2026
8.8 out of 10, Excellent, (37)
8.8/10
Excellent
(37)
The price is $78
$78
$88 total
includes taxes & fees
Jan 20 - Jan 21, 2026
8.8 out of 10, Excellent, (671)
8.8/10
Excellent
(671)
The price is $85
$85
$96 total
includes taxes & fees
Jan 4 - Jan 5, 2026
7.2 out of 10, Good, (90)
7.2/10
Good
(90)
The price is $85
$85
$95 total
includes taxes & fees
Dec 28 - Dec 29
SureStay Hotel by Best Western Manning
SureStay Hotel by Best Western Manning2.5 star property
Manning
8.6 out of 10, Excellent, (1002)
8.6/10
Excellent
(1002)
The price is $89
$89
$99 total
includes taxes & fees
Jan 1 - Jan 2, 2026
8.6 out of 10, Excellent, (489)
8.6/10
Excellent
(489)
The price is $89
$89
$103 total
includes taxes & fees
Jan 4 - Jan 5, 2026
7.2 out of 10, Good, (601)
7.2/10
Good
(601)
The price is $97
$97
$108 total
includes taxes & fees
Jan 8 - Jan 9, 2026
8.8 out of 10, Excellent, (701)
8.8/10
Excellent
(701)
The price is $107
$107
$120 total
includes taxes & fees
Jan 8 - Jan 9, 2026
8.2 out of 10, Very Good, (142)
8.2/10
Very Good
(142)
The price is $104
$104
$116 total
includes taxes & fees
Dec 28 - Dec 29
7.6 out of 10, Good, (15)
7.6/10
Good
(15)
The price is $114
$114
$128 total
includes taxes & fees
Jan 2 - Jan 3, 2026
9.2 out of 10, Wonderful, (881)
9.2/10
Wonderful
(881)
The price is $115
$115
$129 total
includes taxes & fees
Jan 4 - Jan 5, 2026
10.0 out of 10, Exceptional, (284)
10/10
Exceptional
(284)
The price is $117
$117
$132 total
includes taxes & fees
Jan 5 - Jan 6, 2026
8.4 out of 10, Very Good, (1001)
8.4/10
Very Good
(1001)
The price is $119
$119
$132 total
includes taxes & fees
Jan 5 - Jan 6, 2026
9.4 out of 10, Exceptional, (452)
9.4/10
Exceptional
(452)
The price is $125
$125
$140 total
includes taxes & fees
Jan 2 - Jan 3, 2026
8.4 out of 10, Very Good, (163)
8.4/10
Very Good
(163)
The price is $134
$134
$150 total
includes taxes & fees
Dec 28 - Dec 29
10.0 out of 10, Exceptional, (13)
10/10
Exceptional
(13)
The price is $165
$165
$185 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Mayesville
Family friendly
Pet friendly
Learn more about Mayesville
The region around Mayesville is home to attractions such as Riley Field and O'Donnell House.
Photo by Caroline Nunez
Open Photo by Caroline Nunez
Check out reviews of Mayesville hotels guests love
SpringHill Suites Sumter
10/10 Excellent
"Clean, large room. Appreciate the set up and separate bathroom "
Hyatt Place Sumter / Downtown
10/10 Excellent
"Great space good breakfast and spacious rooms clean and comfortable "
Hampton Inn Sumter
10/10 Excellent
"Truly enjoy staying here, the staff is extremely friendly and understanding! It is very clean and comfortable! "
Hampton Inn Manning
10/10 Excellent
"Staff is always super friendly!"
Holiday Inn Express Sumter by IHG
10/10 Excellent
"My room was spotless. The staff was friendly and the breakfast was awesome. I will definitely be staying at the Holiday Inn Express during my travels. "
SureStay Hotel by Best Western Manning
10/10 Excellent
"The room was spotless, very clean. The young man at the front desk was very kind and professional. The young lady at the front desk when we checked out was very kind and professional as well. We enjoyed the comfy Beds and space in the room"
Best Inn of Manning
10/10 Excellent
"Worst experience ever roaches in room 250 moved to 160 much better needs to upgrade rooms not just paint over the mess pull up all carpeting "
1912 Bed and Breakfast
10/10 Excellent
"Good "
Tru by Hilton Sumter
10/10 Excellent
"Rooms are small, no coffe maker or microwave in my room"
Frequently asked questions
What hotels do travelers like in Mayesville?
Guests like Hyatt Place Sumter / Downtown, Super 8 by Wyndham Sumter and 1912 Bed and Breakfast.
Can I book a refundable accommodation in Mayesville?
If you need the flexibility to change your travel plans to Mayesville, most hotels offer refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in Mayesville be like during my vacation?
July and August are typically the warmest months in Mayesville when the average temp is 79°F. January and February are the coldest months when the average temperature is 50°F. August and July are the months with the most rain.
Why should I book my Mayesville hotel through Hotels.com?
There are lots of reasons to book your Mayesville trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.