Photo by Holly Smith
Hotels in Saint Leo
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Quality Inn Zephyrhills - Dade City
Quality Inn Zephyrhills - Dade City
2.5 star property
Zephyrhills
7.8 out of 10, Good, (1001)
7.8/10
Good
(1001)
The price is $93
$93
$108 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Hampton Inn Brooksville Dade
Hampton Inn Brooksville Dade
2.5 star property
Brooksville
9.0 out of 10, Wonderful, (444)
9.0/10
Wonderful
(444)
The price is $110
$110
$123 total
includes taxes & fees
Dec 30 - Dec 31
Roadstar Hotel Zephyrhills
Roadstar Hotel Zephyrhills
2.0 star property
Zephyrhills
9.2 out of 10, Wonderful, (1097)
9.2/10
Wonderful
(1097)
The price is $95
$95
$111 total
includes taxes & fees
Dec 25 - Dec 26
Microtel Inn & Suites by Wyndham Brooksville
Microtel Inn & Suites by Wyndham Brooksville
2.0 star property
Brooksville
8.4 out of 10, Very Good, (1002)
8.4/10
Very Good
(1002)
The price is $84
$84
$94 total
includes taxes & fees
Dec 28 - Dec 29
Holiday Inn Express Hotel & Suites Brooksville by IHG
Holiday Inn Express Hotel & Suites Brooksville by IHG
2.5 star property
Brooksville
8.6 out of 10, Excellent, (728)
8.6/10
Excellent
(728)
The price is $107
$107
$119 total
includes taxes & fees
Dec 28 - Dec 29
Days Inn by Wyndham Brooksville/Dade City
Days Inn by Wyndham Brooksville/Dade City
2.0 star property
Brooksville
7.0 out of 10, Good, (1000)
7.0/10
Good
(1000)
The price is $75
$75
$83 total
includes taxes & fees
Dec 25 - Dec 26
SPOT X Hotel Tampa - Wesley Chapel by The Red Collection
SPOT X Hotel Tampa - Wesley Chapel by The Red Collection
3.0 star property
Wesley Chapel
8.4 out of 10, Very Good, (1009)
8.4/10
Very Good
(1009)
The price is $94
$94
$105 total
includes taxes & fees
Dec 30 - Dec 31
Quality Inn & Suites Brooksville I-75/Dade City
Quality Inn & Suites Brooksville I-75/Dade City
2.5 star property
Brooksville
6.8 out of 10, (775)
6.8/10
(775)
The price is $71
$71
$80 total
includes taxes & fees
Dec 30 - Dec 31
Best Western Wesley Chapel
Best Western Wesley Chapel
2.5 star property
Wesley Chapel
8.2 out of 10, Very Good, (1001)
8.2/10
Very Good
(1001)
The price is $104
$104
$116 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Liberty Hill Executive Inn
Liberty Hill Executive Inn
2.0 star property
Zephyrhills
7.4 out of 10, Good, (3)
7.4/10
Good
(3)
The price is $114
$114
$128 total
includes taxes & fees
Dec 25 - Dec 26
WoodSpring Suites Wesley Chapel-Tampa
WoodSpring Suites Wesley Chapel-Tampa
2.5 star property
Wesley Chapel
7.6 out of 10, Good, (767)
7.6/10
Good
(767)
The price is $79
$79
$88 total
includes taxes & fees
Dec 25 - Dec 26
Hampton Inn Dade City - Zephyrhills
Hampton Inn Dade City - Zephyrhills
2.5 star property
Dade City
8.8 out of 10, Excellent, (784)
8.8/10
Excellent
(784)
The price is $113
$113
$127 total
includes taxes & fees
Jan 22 - Jan 23, 2026
Rodeway Inn Wesley Chapel
Rodeway Inn Wesley Chapel
2.0 star property
Wesley Chapel
6.2 out of 10, (966)
6.2/10
(966)
The price is $79
$79
$88 total
includes taxes & fees
Dec 25 - Dec 26
Microtel Inn & Suites by Wyndham Zephyrhills
Microtel Inn & Suites by Wyndham Zephyrhills
2.0 star property
Zephyrhills
8.0 out of 10, Very Good, (1000)
8.0/10
Very Good
(1000)
The price is $100
$100
$114 total
includes taxes & fees
Dec 28 - Dec 29
Econo Lodge Wesley Chapel I-75
Econo Lodge Wesley Chapel I-75
2.0 star property
Wesley Chapel
6.6 out of 10, (765)
6.6/10
(765)
The price is $71
$71
$79 total
includes taxes & fees
Dec 30 - Dec 31
SpringHill Suites by Marriott Tampa North/I 75 Tampa Palms
SpringHill Suites by Marriott Tampa North/I 75 Tampa Palms
3.0 star property
New Tampa
9.0 out of 10, Wonderful, (1000)
9.0/10
Wonderful
(1000)
The price is $115
$115
$130 total
includes taxes & fees
Dec 30 - Dec 31
Fairfield Inn & Suites by Marriott Tampa Wesley Chapel
Fairfield Inn & Suites by Marriott Tampa Wesley Chapel
2.5 star property
Wesley Chapel
9.2 out of 10, Wonderful, (721)
9.2/10
Wonderful
(721)
The price is $125
$125
$140 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hyatt Place Tampa/Wesley Chapel
Hyatt Place Tampa/Wesley Chapel
3.0 star property
Lutz
9.2 out of 10, Wonderful, (1001)
9.2/10
Wonderful
(1001)
The price is $144
$144
$161 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Holiday Inn Express Hotel & Suites New Tampa I-75 by IHG
Holiday Inn Express Hotel & Suites New Tampa I-75 by IHG
3.5 star property
New Tampa
9.2 out of 10, Wonderful, (913)
9.2/10
Wonderful
(913)
The price is $118
$118
$134 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Saddlebrook Resort
Saddlebrook Resort
4.0 star property
Wesley Chapel South
8.0 out of 10, Very Good, (5)
8.0/10
Very Good
(5)
The price is $199
$199
$253 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Saint Leo
Family friendly
Pet friendly
Learn more about Saint Leo
The region around Saint Leo is home to attractions such as Dade City Atlantic Coast Line Railroad Depot and Wesley Chapel District Park.
Photo by Holly Smith
Open Photo by Holly Smith
Check out reviews of Saint Leo hotels guests love
Holiday Inn Express Hotel & Suites New Tampa I-75 by IHG
10/10 Excellent
"Clean room"
Roadstar Hotel Zephyrhills
10/10 Excellent
"Great"
SpringHill Suites by Marriott Tampa North/I 75 Tampa Palms
10/10 Excellent
"The rooms were clean staff were very friendly and common areas were clean "
SPOT X Hotel Tampa - Wesley Chapel by The Red Collection
10/10 Excellent
"Meli was great as usual!! "
Days Inn by Wyndham Brooksville/Dade City
10/10 Excellent
"Yes"
Holiday Inn Express & Suites Tampa North - Wesley Chapel by IHG
10/10 Excellent
"The staff is one the friendliest I have encountered."
Best Western Wesley Chapel
10/10 Excellent
"I've never seen a hotel so clean. As a 30-year veteran in quality assurance I'm not easily impressed but this hotel was fantastic."
WoodSpring Suites Wesley Chapel-Tampa
10/10 Excellent
"Great "
Fairfield Inn & Suites by Marriott Tampa Wesley Chapel
10/10 Excellent
"Great hotel and staff "
Frequently asked questions
What hotels do travelers like in Saint Leo?
Can I book refundable hotels in Saint Leo?
If you're looking for the flexibility to change your plans to Saint Leo, most hotels provide refundable* rates you can book. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in Saint Leo be like during my trip?
August and July are typically the warmest months in Saint Leo when the average temp is 81°F. January and February are the coldest months when the average temperature is 63°F. August and July are the months with the most rain.
Why should I book my Saint Leo hotel with Hotels.com?
There are lots of reasons to book your Saint Leo trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.