Hotels in Roxana

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An outdoor patio area with multiple tables and chairs, surrounded by neatly trimmed bushes and a gravel path.

A hotel room with a bed, a sofa, a small table, and a painting on the wall.

A parking area with electric vehicle charging stations, marked parking spaces, and a chain-link fence.

A modern building with a blue and white color scheme, labeled "The Great Rivers." It features a parking lot with several cars and a gas station in the foreground.

1. The Great Rivers, an Ascend Collection Hotel

Alton

$87

$99 total

includes taxes & fees

Oct 19 - Oct 20

A multi-story hotel with balconies, a parking lot with marked spaces, and a clear sky.

A red door with a prohibition sign against tobacco, e-cigarettes, and cannabis.

A long, straight corridor with a series of doors on one side and a black railing on the other.

A hotel room with two beds, each with a wooden headboard, white bedding, and a patterned bedspread.

2. Bel Air Motel

Wood River

$72

$89 total

includes taxes & fees

Sep 29 - Sep 30

A hotel lobby with blue seating, a flat-screen TV, and a fireplace.

A hotel room with a large bed, two bedside tables, a desk, and a chair.

A reception area with two dark wooden reception desks, a stone-textured wall, and a sign reading "Comfort INN".

An indoor swimming pool with clear water, surrounded by lounge chairs and a tiled deck.

3. Comfort Inn Edwardsville - St. Louis

Edwardsville

$95

$109 total

includes taxes & fees

Oct 18 - Oct 19

A modern lobby with patterned armchairs, a fireplace, and a large TV on the wall.

A garden with a stone wall, a wooden pergola, and yellow daffodils.

A modern lobby with a blue patterned carpet, a white sofa, patterned armchairs, and a decorative mirror.

A lobby with a sofa, armchairs, a chandelier, decorative mirrors, and a fireplace.

4. Holiday Inn Express & Suites Edwardsville by IHG

Edwardsville

$131

$151 total

includes taxes & fees

Oct 18 - Oct 19

A brick building with a wooden gazebo in front.

A statue of a Native American figure with a horse, a Route 66 sign, a map, and a clock on the wall.

A compact kitchen with a sink, microwave, and stove, a wooden cabinet, and a television mounted on the wall.

A spacious dining area with multiple round tables and chairs, a fireplace, and large windows with curtains.

5. Country Hearth Inn & Suites Edwardsville St. Louis

Edwardsville

$129

$148 total

includes taxes & fees

Sep 29 - Sep 30

A hotel entrance with a covered driveway and a parking area.

A hotel room with two beds, a TV, a desk, and a chair.

A hotel lobby with striped armchairs, a round coffee table, a sofa, and a clock on the wall.

A dining area with multiple tables and chairs, a kitchen in the background, and artwork on the walls.

6. Best Western Plus Parkway Hotel

Alton

$85

$96 total

includes taxes & fees

Oct 12 - Oct 13

A modern bathroom with a red bathtub, a white sink, and a shower. There is a bed with a white mattress and a grey curtain in the adjacent room.

A spacious interior with a high ceiling, a staircase with wooden balusters, and a modern kitchen area in the background.

A modern kitchen area with a dining table and chairs, a refrigerator, a coffee machine, and a vending machine.

A modern kitchen with stainless steel appliances, a white countertop, and a framed picture on the wall.

7. Red Lion Inn & Suites Pontoon Beach

Granite City

$72

$82 total

includes taxes & fees

Sep 29 - Sep 30

A hotel room with a bed, a desk with a TV, a chair, a sofa, and a window with curtains.

8. Hampton Inn & Suites St. Louis/Alton

Alton

$128

$146 total

includes taxes & fees

Oct 19 - Oct 20

A modern living room with a stone fireplace, a reception desk, and a large window.

A modern living room with a stone fireplace, green and beige sofas, a round coffee table, and large windows offering a view of trees.

A Fairfield by Marriott hotel with a modern design, featuring a covered entrance and multiple floors.

A modern lobby with a blue sofa, a white coffee table, and a reception desk in the background.

9. Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City

Granite City

$105

$117 total

includes taxes & fees

Oct 11 - Oct 12

An outdoor patio with a circular fire pit, seating, and a grill area.

A modern hotel room with a sectional sofa, a small table, a lamp, and a large window with sheer curtains.

A multi-story hotel with a covered entrance and a sign reading "Towneplace Suites by Marriott".

A modern kitchen with stainless steel appliances, wooden cabinets, and a countertop with a coffee maker and mugs.

10. TownePlace Suites by Marriott St. Louis Edwardsville, IL

Edwardsville

$161

$185 total

includes taxes & fees

Oct 18 - Oct 19

An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and large windows offering views of the outside.

A hotel room with a Samsung monitor displaying a hotel booking site, a smaller monitor, a keyboard, a mouse, and a printer.

A Best Western hotel with a large sign, multiple parking spaces, and a well-lit entrance.

A hotel room with a bed, a desk, a chair, and a small table.

11. Best Western Troy Hotel

Troy

$99

$110 total

includes taxes & fees

Sep 29 - Sep 30

A spacious lobby with a high ceiling, large windows, and a variety of seating options including sofas and chairs.

A spacious indoor area with a large table and chairs, a sofa, and a staircase leading to an upper level.

An indoor swimming pool with clear glass walls, a tiled edge, and a ceiling with metal beams. There are lounge chairs and tables around the pool area.

A hotel room with a large bed, a desk, a chair, and a television.

12. Drury Inn & Suites St. Louis Collinsville

Eastport

$111

$128 total

includes taxes & fees

Oct 11 - Oct 12

An indoor swimming pool with a lifeguard chair, a lifebuoy, and a mural of a beach scene.

A reception desk with a wooden counter, two HP laptops, a telephone, and a framed black and white photo on the wall.

A breakfast area with a wooden counter, a microwave, and a coffee machine.

A hotel room with two beds, a desk with a TV, a chair, and a window with a view of the outside.

13. Super 8 by Wyndham Troy IL/St. Louis Area

Troy

$64

$71 total

includes taxes & fees

Oct 4 - Oct 5

A Holiday Inn Express & Suites building with a modern design, featuring a covered entrance and a landscaped area with trees.

A modern hotel corridor with a wooden reception desk, a staircase, and a snack bar with various packaged foods.

A modern breakfast area with a counter displaying various food items and a sign reading "EXPRESS START BREAKFAST".

Two reception desks with a modern design, a blue geometric wall in the background, and a sign indicating the hotel name.

14. Holiday Inn Express and Suites Alton St Louis Area by IHG

Alton

$118

$135 total

includes taxes & fees

Oct 18 - Oct 19

A hotel room with a bed, a desk with a television, a chair, a desk lamp, and a wall-mounted rack with keys.

A swimming pool with a clear blue water, surrounded by lounge chairs and a sunbed.

A hotel lobby with a reception desk, seating area, and a bakery display.

A modern office space with a desk, computer, and a large window.

15. Red Roof Inn St Louis - Troy, IL

Troy

$65

$72 total

includes taxes & fees

Oct 5 - Oct 6

A buffet area with a wooden counter, various food items, and a coffee station.

A reception area with a wooden reception desk, a stone wall with a clock, and framed pictures on the wall.

A hotel room with two beds, a sofa, a desk, and a window with curtains.

A hotel room with a sofa, a small table, a lamp, and a TV.

16. Comfort Inn Collinsville near St. Louis

Eastport

$107

$123 total

includes taxes & fees

Oct 19 - Oct 20

A reception area with a counter, a digital screen, and a cityscape painting.

A reception area with a coffee station, seating, a TV, and a staircase.

A hotel room with two beds, a desk, and a window with curtains.

Vending machines with Coca-Cola branding and a sign advising not to fill ice chests.

17. Motel 6 Troy, IL

Troy

$70

$78 total

includes taxes & fees

Oct 12 - Oct 13

A modern hotel room with a large bed, a blue chair, and a wall-mounted TV.

A kitchen with a microwave, a refrigerator, and a coffee station.

A modern hotel lobby with a kitchen area, multiple seating arrangements, and framed artwork on the walls.

18. Days Inn by Wyndham Collinsville/St. Louis

Eastport

$65

$75 total

includes taxes & fees

Oct 13 - Oct 14

A lobby with a central table, seating area, and a stone pillar with a mirror.

A restaurant with multiple tables, chairs, and a stone fireplace.

A modern hotel lobby with a sectional sofa, armchairs, a coffee table, and abstract wall art.

An indoor swimming pool with clear water, surrounded by lounge chairs and potted plants.

19. DoubleTree by Hilton Collinsville - St. Louis

Eastport

$123

$141 total

includes taxes & fees

Oct 18 - Oct 19

A rooftop terrace with wicker furniture, offering a city view.

A spacious lobby with a blue sofa, a glass coffee table, and a chandelier.

A hotel room with a large window offering a view of the Gateway Arch and a modern building.

A lobby with seating areas, a chandelier, and a large pillar.

20. Drury Plaza Hotel St. Louis at the Arch

Downtown St. Louis

$135

$158 total

includes taxes & fees

Oct 2 - Oct 3

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Go beyond your typical stay in Roxana

Pet friendly

Apartment

Pool

Hot tub

Family friendly

Cottage

Top landmarks in Roxana

Wood River Refinery History Museum

Wood River Refinery History Museum is 0.8 mi (1.3 km) from central Roxana, why not stop by during your stay. If you want to experience more of the culture Roxana has to offer, head to Lewis and Clark Confluence Tower, Lewis and Clark Interpretive Center, and Columbia Bottom Conservation Area.

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Roxana Village Hall

Roxana Village Hall is worth a visit, located 1 mi (1.6 km) from central Roxana.

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Charles Raich Field

You can catch an event at Charles Raich Field, located 0.7 mi (1.2 km) from central Roxana.

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Burbank Park

Burbank Park is worth a visit, located 1 mi (1.5 km) from central Roxana.

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Check out reviews of Roxana hotels guests love

Home2 Suites by Hilton St. Louis Downtown

8/10 Good

"Clean rooms, friendly helpful staff, nice complimentary breakfast and nighttime security make this hotel an incredible value. The location is great too. The beds and pillows are not comfortable but they were very clean. This is not really an issue if traveling for business. I recommend this property."

Courtyard by Marriott St. Louis Downtown/Convention Center

10/10 Excellent

"Great staff"

Live by Loews - St.Louis

10/10 Excellent

"Great stay!"

Drury Plaza Hotel St. Louis at the Arch

8/10 Good

"The location was great for downtown attractions. Although there was no baseball game when we were there that whole area looked nice. We stayed in a room overlooking the arch…just note the traffic noise for the adjacent highway was substantial but the morning sunrises beautiful. Also, there is great value for families here. Between the breakfast and dinner Kickback there was a lot of free food provided. Staff very friendly."

Pear Tree Inn St. Louis Airport

10/10 Excellent

"The room was very nice especially for the price. Airport shuttle was helpful."

The Cheshire

8/10 Good

"The staff, lobby, breakfast were all good. The room was mid-tier, however. Not bad, but still a bit pricey for what it was."

Pear Tree Inn St. Louis Near Union Station

8/10 Good

"I would go back and stay again because the overall experience was good."

Forest Park Hotel by MDR

8/10 Good

"I was only there to sleep and did not use any of the amenities. The noise from the highway and the trains was louder than at most hotels I have stayed at."

Hyatt Regency St. Louis at The Arch

10/10 Excellent

"Great stay with a great view and amenities…."

Frequently asked questions

Can I book a refundable accommodation in Roxana?

If you want the flexibility to change your plans to Roxana, most accommodations provide refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.

What will the weather in Roxana be like during my visit?

July and August are typically the warmest months in Roxana when the average temp is 75°F. January and February are the coldest months when the average temperature is 36°F. May and April are the months with the most rain.

Why should I book my Roxana hotel with Hotels.com?

There are lots of reasons to book your Roxana trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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