Hotels in Irene

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Where to stay in Irene?

A hotel room with two beds, a large framed waterfall painting, a lamp, and a window with curtains.

A hotel sign with the name "Super 8" and a blank board below it.

A reception area with a counter, seating, and a television.

A lobby with a reception desk, two armchairs, a coffee table, and potted plants.

1. Super 8 by Wyndham Beresford

Beresford

$66

$72 total

includes taxes & fees

Sep 20 - Sep 21

A hotel room with two beds, a desk, a chair, a window with curtains, a wall-mounted TV, and a large wall art piece.

A breakfast area with a coffee machine, a TV, and a clock on the wall.

A bathroom with a sink, mirror, towel rack, toilet, and shower curtain.

A multi-story hotel with a covered entrance, stone accents, and a parking lot.

2. Super 8 by Wyndham Yankton

Yankton

$78

$87 total

includes taxes & fees

Sep 8 - Sep 9

An indoor swimming pool with clear blue water, surrounded by white chairs and tables.

A compact kitchenette with a microwave, coffee maker, and dishwasher. Adjacent is a small seating area with a sofa and a table.

A hotel room with a desk, two chairs, a sofa, a lamp, and a window with curtains.

A hotel room with a bed, a desk with a television, a chair, a lamp, and a window with curtains.

3. Holiday Inn Express & Suites Yankton by IHG

Yankton

$118

$130 total

includes taxes & fees

Sep 10 - Sep 11

A lobby with a stone fireplace, leather seating, a bar area, and a staircase.

A bar area with a long counter, multiple stools, and hanging glassware.

A modern living room with a sofa set, a coffee table, and a rug.

A Best Western hotel with a modern facade, large glass windows, and a well-lit entrance.

4. Best Western Kelly Inn

Yankton

$106

$117 total

includes taxes & fees

Sep 10 - Sep 11

A modern living room with a fireplace, seating area, and large windows.

A patio with outdoor seating, stone wall, and large windows.

A restaurant with a long counter, booths, and high tables.

A modern reception area with wooden paneling, a reception desk, and a refrigerated display case.

5. Fairfield Inn & Suites by Marriott Yankton

Yankton

$139

$153 total

includes taxes & fees

Sep 6 - Sep 7

A hotel lobby with a reception desk, seating area, and a large window with a view of a building.

A hotel room with two beds, a desk, a chair, and a framed picture on the wall.

A Comfort Inn hotel with a covered entrance, a parking lot, and a clear sky.

A hotel reception area with a long counter, coffee machines, and a television screen displaying a program.

6. Comfort Inn Yankton SD

Yankton

$110

$121 total

includes taxes & fees

Oct 5 - Oct 6

A hotel room with two beds, a desk, a chair, and a lamp.

A living room with a brown leather sofa, a brown leather armchair, a round coffee table, a red doormat, a window with curtains, and an air conditioning unit.

A hotel room with a sofa, a television, a desk with a chair, a lamp, a microwave, a framed picture, and a fireplace.

A hotel room with a corner bathtub, a refrigerator, a microwave, a lamp, and a map on the wall.

7. Econo Lodge Inn & Suites Yankton

Yankton

$77

$85 total

includes taxes & fees

Sep 28 - Sep 29

A spacious kitchen with a large island, modern pendant lights, and a ceiling fan.

A modern kitchen with stainless steel appliances, dark wood cabinets, and a tiled floor.

A spacious room with wooden walls and ceiling, featuring a large chandelier, multiple windows, and a central seating area with tables and chairs.

A modern kitchen with dark cabinets, stainless steel appliances, and a large window.

8. Lewis and Clark Resort

Yankton

$99

$105 total

includes taxes & fees

Sep 7 - Sep 8

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Go beyond your typical stay in Irene

Pet friendly

Check out reviews of Irene hotels guests love

Lewis and Clark Resort

10/10 Excellent

"Great views..very adequate accommodations..huge outlying natural area to relax in..do it again!"

Fairfield Inn & Suites by Marriott Yankton

10/10 Excellent

"Everything was great! Couldn’t quite figure out how to keep the room temp consistent with the air conditioning at night (I need it cold) but no complaints!"

Best Western Kelly Inn

10/10 Excellent

"Great place. I’ll be back"

Econo Lodge Inn & Suites Yankton

8/10 Good

"Good and clean staff was not always around."

Super 8 by Wyndham Beresford

10/10 Excellent

"Nothing special"

Frequently asked questions

Can I book refundable hotels in Irene?

If you're looking for the flexibility to change your plans to Irene, most accommodations provide refundable* bookable rates. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.

What will the weather in Irene be like during my vacation?

July and August are typically the warmest months in Irene when the average temp is 72°F. January and February are the coldest months when the average temperature is 26°F. June and May are the months with the most rain.

Why should I book my Irene accommodation with Hotels.com?

There are lots of reasons to book your Irene trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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