Hotels in Puxico

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Where to stay in Puxico?

A reception desk with a wooden panel design, a white vase with flowers, and a 'Hilton HONOR' sign.

A modern kitchen with a bar area, bar stools, wine bottles, and a large TV.

A hotel room with two beds, a desk, a chair, a small table, a lamp, and a window with curtains.

A modern interior with a seating area, tables, and a large screen.

1. Hampton Inn By Hilton Dexter

Dexter

$98

$111 total

includes taxes & fees

Nov 1 - Nov 2

A diner with booth seating, a checkered floor, and a counter with a cash register.

A lobby with a round rug, two potted plants, three framed artworks, and two black leather chairs.

A gym with multiple exercise machines, a clock on the wall, and a window with blinds.

A hotel room with a bed, a desk, a chair, a large mirror, a sink, and a trash bin.

2. Travelodge by Wyndham Dexter

Dexter

$83

$94 total

includes taxes & fees

Oct 25 - Oct 26

A spacious lobby with a reception desk, seating area, and large windows.

A spacious conference room with brick walls, multiple tables and chairs, a large window, and a mounted TV.

An indoor swimming pool with a clear view of the outside through large windows.

A hotel room with a bed, a desk, a chair, a sofa, and a TV.

3. Drury Inn & Suites Poplar Bluff

Poplar Bluff

$94

$106 total

includes taxes & fees

Oct 25 - Oct 26

A modern lounge area with a stone fireplace, blue seating, a round coffee table, and a large window offering a view.

An outdoor patio with a table and chairs, a large umbrella, and a glass door leading to an interior space.

A reception desk with a bicycle light, potted plants, and a 'Connect & Print' sign.

A corner market with a refrigerated display case and a pantry area.

4. Fairfield Inn & Suites by Marriott Poplar Bluff

Poplar Bluff

$97

$109 total

includes taxes & fees

Nov 1 - Nov 2

A coffee shop with a coffee machine, espresso cups, a sink, and a trash bin.

A hotel room with two beds, a desk with a lamp, a chair, a dresser, and a door with a handle.

A hotel lobby with a reception desk, a waiting area with a sofa and armchairs, and a patterned carpet.

A hotel hallway with patterned carpet, light green walls, and a ceiling with recessed lighting.

5. Dexter Inn

Dexter

$69

$78 total

includes taxes & fees

Oct 20 - Oct 21

A hotel room with two beds, a nightstand, and a wall-mounted light fixture.

A laundry area with two front-loading washing machines, a metal drying rack, and a wall with a blue abstract pattern.

A compact kitchen with a microwave, a sink, and a small refrigerator.

A modern dining area with wooden tables and chairs, a mounted television, and a coffee station with various drink options.

6. Hampton Inn Poplar Bluff

Poplar Bluff

$91

$102 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with a bed, a desk, a chair, a bathroom with a bathtub, and a patterned floor.

A hotel reception area with a reception desk, framed certificates, and a painting on the wall.

A kitchen with wooden cabinets, a stainless steel sink, a microwave, and a dishwasher.

A hotel with a brick facade, multiple windows, and a covered entrance area.

7. Econo Lodge Dexter

Dexter

$51

$58 total

includes taxes & fees

Nov 17 - Nov 18

A modern kitchen with a coffee machine, a sink, and a counter. There are four chairs and a table in the dining area.

A motel with a prominent '66' sign, large windows, and a flat roof.

A hotel reception area with a modern design, featuring a reception desk, a glass door, and a wall with framed pictures and a large number '6' sign.

A hotel room with two beds, a desk, a chair, a TV mounted on the wall, and a mirror.

8. Motel 6 Poplar Bluff, MO

Poplar Bluff

$77

$86 total

includes taxes & fees

Oct 21 - Oct 22

A modern dining area with a long table and four chairs, a flat-screen TV on the wall, and recessed ceiling lighting.

A hotel room with two beds, a bedside lamp, a bench, a mirror, and a door leading to another room.

A hotel room with a desk, chair, and a small seating area. It includes a microwave, coffee maker, and a refrigerator.

A hotel room with a sofa, a small table, a chair, a desk, two lamps, a window with curtains, and a framed picture on the wall.

9. Holiday Inn Poplar Bluff by IHG

Poplar Bluff

$84

$95 total

includes taxes & fees

Nov 8 - Nov 9

A hotel room with two beds, a TV, a mirror, a wardrobe, and a desk.

A window with a view of a parking lot and buildings, a welcome sign, and a credit card machine.

A row of single-story brick buildings with attached garages, likely a motel or small hotel, with a parking lot in front and a grassy area with a gazebo.

A Hickory House Inn with a clear sky, a parking lot, and a covered entrance.

10. OYO Hickory House Inn

Dexter

$58

$72 total

includes taxes & fees

Oct 20 - Oct 21

A hotel lobby with a reception desk, a blue sofa, a fireplace, and a television.

A hotel room with a bed, two armchairs, a sofa, a small table, a TV, a ceiling fan, and a window with curtains.

A hotel with a covered entrance, multiple windows, and a yellow facade.

A hotel lobby with a coffee station, seating area, and a television screen.

11. Comfort Inn Poplar Bluff North

Poplar Bluff

$75

$84 total

includes taxes & fees

Nov 8 - Nov 9

A hotel room with a bed, two bedside lamps, a framed picture of a building, and a nightstand with a phone.

A two-story motel with a covered parking area and a bench outside.

A lobby with a reception desk, a Coca-Cola vending machine, a snack vending machine, and a seating area with a round table.

A laundry area with two stacked washers and dryers, a control panel, and a beige wall with a wooden panel above the dryers.

12. Super 8 by Wyndham Poplar Bluff Missouri

Poplar Bluff

$55

$62 total

includes taxes & fees

Nov 19 - Nov 20

A rustic cabin with a metal roof, surrounded by a wooden deck and picnic tables, set in a forested area.

A calm lake with a wooden dock and a forested island in the distance.

A wooden deck with a railing leading to a building with a metal roof and a brown door.

13. Lake Wappapello

Williamsville

$100

$105 total

includes taxes & fees

Oct 20 - Oct 21

A living room with a blue wall, a fireplace, a sofa, and a chair.

A brick building with a sign reading "Mercantile & Hotel".

A hotel room with two beds, a vanity with a mirror, a chair, and a dresser.

A sign for EC REED'S MERCANTILE & HOTEL with a geometric design.

14. EC Reed's Mercantile and Hotel

Marble Hill

$105

$114 total

includes taxes & fees

Oct 20 - Oct 21

A spacious living area with a dark grey sofa set, a matching ottoman, and a wooden-paneled wall.

A house with a red door, a porch with rocking chairs, and a wreath on the door.

A two-story house with a deck and a covered porch.

A spacious dining area with a stone wall, wooden furniture, and a fireplace.

15. 40-acre Poplar Bluff Nature Lovers Paradise!

Poplar Bluff

$120

$297 total

includes taxes & fees

Oct 21 - Oct 22

View all properties

Go beyond your typical stay in Puxico

Pet friendly

Pool

Family friendly

Learn more about Puxico

Puxico is well-known for its attractions such as Mark Twain National Forest and Mingo Wilderness.

See all hotels in Puxico

A night scene with a clear sky, a crescent moon, and two silhouetted trees against a twilight sky.

Check out reviews of Puxico hotels guests love

Hampton Inn Poplar Bluff

8/10 Good

"The hotel needs some TLC, a little rough around the edges, but is was a nice stay, comfortable beds, clean, good breakfast."

Drury Inn & Suites Poplar Bluff

10/10 Excellent

"Everything was wonderful, highly recommended"

Holiday Inn Poplar Bluff by IHG

10/10 Excellent

"Quick service. Friendly staff. Very nice room"

Fairfield Inn & Suites by Marriott Poplar Bluff

10/10 Excellent

"Everything was great- breakfast, cleanliness, price— will stay there again"

Hampton Inn By Hilton Dexter

8/10 Good

"I was disappointed that there was no Bible in my room. I would hope they would consider putting Bibles in each room."

EC Reed's Mercantile and Hotel

10/10 Excellent

"On street parking, quiet little town, absolutely beautiful little hotel, diner, and general store. Very unique! It’s a whole experience staying here. I would love an opportunity to stop here again if I’m ever going through this area again."

Lake Wappapello

10/10 Excellent

"This a cabin in a state park. It was very clean and had newer upgrades. Bring the food you need because it's fairly distance from a grocery. We came later in the day because we needed one night and this was a great price and not a chain hotel which we like. There is a little store not too far from the park. We ordered deli sandwiches from here and picked up some icecream. The sandwiches were delicious and the store had pretty much whatever you might need. The checkin process was great with good communication about which cabin to go to, what the door code was etc... We plan to come back for a longer stay so we can have another evening around the firepit and see all of the stars. Great place to stay."

Frequently asked questions

What hotels do travelers like in Puxico?

Guests like 'the Lakehouse' Lovely Wappapello Country Home!.

Can I book a refundable accommodation in Puxico?

If you want the flexibility to change your travel plans to Puxico, most accommodations provide refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.

What will the weather in Puxico be like during my visit?

The warmest months in Puxico are usually July and August with an average temp of 77°F. January and February are the chilliest months when the average temp is 41°F. The rainiest months are April and May.

Why should I book my Puxico hotel through Hotels.com?

There are plenty of reasons to book your Puxico travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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