Hotels in Santa Ana

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Where to stay in Santa Ana?

Ixpanpajul
Ixpanpajul
3.0 star property
Flores
8.2 out of 10, Very Good, (33 reviews)
The price is $120
$146 total
includes taxes & fees
Jan 20 - Jan 21
Ixpanpajul
Las Lagunas Boutique Hotel
Las Lagunas Boutique Hotel
4.5 star property
Flores
10.0 out of 10, Exceptional, (354 reviews)
  • cleanliness
    Waterfront boutique luxury in Flores, Guatemala with full-service spa and two bars.
The price is $385
$470 total
includes taxes & fees
Feb 3 - Feb 4
Las Lagunas Boutique Hotel
Hotel Villa Maya
Hotel Villa Maya
3.0 star property
Flores
9.6 out of 10, Exceptional, (192 reviews)
  • cleanliness
    Secluded Mayan oasis offers full-service spa, outdoor pool, and convenient Flores location.
The price is $104
$126 total
includes taxes & fees
Jan 20 - Jan 21
Hotel Villa Maya
Hotel Gringo Perdido
Hotel Gringo Perdido
1.5 star property
San Jose Peten
9.8 out of 10, Exceptional, (57 reviews)
  • cleanliness
    Lakeside retreat with a private beach, pool, and garden views in El Remate.
The price is $139
$218 total
includes taxes & fees
Feb 1 - Feb 2
Hotel Gringo Perdido
Posada del Cerro
Posada del Cerro
2.5 star property
Flores
9.2 out of 10, Wonderful, (10 reviews)
  • cleanliness
    Charming Flores hotel near Biotopo Cerro Cahui with garden retreat and terrace views.
The price is $41
$50 total
includes taxes & fees
Feb 1 - Feb 2
Posada del Cerro
Hotel Camino Real Tikal
Hotel Camino Real Tikal
4.0 star property
San Jose Peten
8.8 out of 10, Excellent, (569 reviews)
  • cleanliness
    Relax by Guatemala's Lake Petén Itzá with kayaking and poolside tranquility.
The price is $113
$137 total
includes taxes & fees
Jan 20 - Jan 21
Hotel Camino Real Tikal
Hotel & Brunch Lirio de los Valles
Hotel & Brunch Lirio de los Valles
3.0 star property
Flores
9.0 out of 10, Wonderful, (6 reviews)
The price is $37
$45 total
includes taxes & fees
Jan 20 - Jan 21
Hotel & Brunch Lirio de los Valles
Hotel Del Patio
Hotel Del Patio
3.0 star property
Flores
8.6 out of 10, Excellent, (341 reviews)
  • cleanliness
    Tranquil garden retreat in Flores with convenient access to Maya Mall attractions.
The price is $54
$66 total
includes taxes & fees
Jan 20 - Jan 21
Hotel Del Patio
Hotel La Ribiera del Lago Peten Itza
Hotel La Ribiera del Lago Peten Itza
3.0 star property
San Jose Peten
4.8 out of 10, (15 reviews)
  • cleanliness
    Lakeside retreat in Peten with pool, café, and tennis courts for Guatemala explorers.
The price is $74
$90 total
includes taxes & fees
Jan 20 - Jan 21
Hotel La Ribiera del Lago Peten Itza
Hotel Tiffany
Hotel Tiffany
3.0 star property
Flores
10.0 out of 10, Exceptional, (1 review)
The price is $120
$146 total
includes taxes & fees
Feb 9 - Feb 10
Hotel Tiffany
Posada Itza
Posada Itza
3.0 star property
Flores
10.0 out of 10, Exceptional, (1 review)
  • cleanliness
    Tranquil retreat in Flores with easy access to both Central Park and Maya Mall.
The price is $203
$400 total
includes taxes & fees
Jan 20 - Jan 21
Posada Itza
Nakum Hotel
Nakum Hotel
2.0 star property
Flores
7.0 out of 10, Good, (4 reviews)
The price is $41
$50 total
includes taxes & fees
Jan 20 - Jan 21
Nakum Hotel
Hotel Tepeu
Hotel Tepeu
2.5 star property
Flores
9.2 out of 10, Wonderful, (107 reviews)
  • cleanliness
    Relaxing lakeside retreat with a refreshing pool bar just minutes from Flores attractions.
The price is $85
$104 total
includes taxes & fees
Feb 1 - Feb 2
Hotel Tepeu
Hotel Maya Internacional
Hotel Maya Internacional
3.0 star property
Flores
7.8 out of 10, Good, (66 reviews)
  • cleanliness
    Modern hotel near Flores airport with massage services and beach access.
The price is $141
$172 total
includes taxes & fees
Jan 20 - Jan 21
Hotel Maya Internacional
Peten Esplendido Hotel and Conference Center
Peten Esplendido Hotel and Conference Center
3.0 star property
Flores
7.6 out of 10, Good, (240 reviews)
  • cleanliness
    An outdoor pool and poolside bar near Maya Mall and Central Park in Flores.
The price is $73
$89 total
includes taxes & fees
Feb 4 - Feb 5
Peten Esplendido Hotel and Conference Center
Casa Ramona
Casa Ramona
3.0 star property
Flores
8.6 out of 10, Excellent, (36 reviews)
  • cleanliness
    Experience the tranquil island of Flores with spa services and easy access to beaches.
The price is $50
$93 total
includes taxes & fees
Jan 24 - Jan 25
Casa Ramona
Hotel Casona del Lago
Hotel Casona del Lago
3.5 star property
Flores
9.0 out of 10, Wonderful, (300 reviews)
  • cleanliness
    Relaxed lakeside hotel with free airport shuttle near Central Park and Maya Mall.
The price is $88
$107 total
includes taxes & fees
Jan 20 - Jan 21
Hotel Casona del Lago
Isla de Flores Hotel
Isla de Flores Hotel
3.5 star property
Flores
9.4 out of 10, Exceptional, (470 reviews)
  • cleanliness
    Free airport shuttle and refreshing pool near Las Guacamayas Biological Station.
The price is $102
$137 total
includes taxes & fees
Jan 20 - Jan 21
Isla de Flores Hotel
Hotel Villa del Lago
Hotel Villa del Lago
3.0 star property
Flores
9.2 out of 10, Wonderful, (44 reviews)
  • cleanliness
    Lakeside retreat with easy access to Flores' historic charm and nearby attractions.
The price is $77
$93 total
includes taxes & fees
Jan 20 - Jan 21
Hotel Villa del Lago
Hotel Casazul
Hotel Casazul
2.5 star property
Flores
8.8 out of 10, Excellent, (214 reviews)
  • cleanliness
    Escape to the heart of Flores with room service and easy access to top attractions.
The price is $78
$95 total
includes taxes & fees
Jan 20 - Jan 21
Hotel Casazul
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Check out reviews of Santa Ana hotels guests love

Frequently asked questions

Can I book a refundable hotel in Santa Ana?
If you want the flexibility to change your travel plans to Santa Ana, most properties offer refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in Santa Ana be like during my trip?
With an average temperature of 73°F during the coldest months, Santa Ana is a great place to visit any time of year.
Why should I book my Santa Ana hotel with Hotels.com?
There are lots of reasons to book your Santa Ana trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.