Hotels in Santa Ana
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Hotel Campestre Santa Ana
Hotel Campestre Santa Ana
3.0 star property
Santa Ana
8.8 out of 10, Excellent, (5)
8.8/10
Excellent
(5)
Ixpanpajul
Ixpanpajul
3.0 star property
Flores
8.2 out of 10, Very Good, (31)
8.2/10
Very Good
(31)
Las Lagunas Boutique Hotel
Las Lagunas Boutique Hotel
4.5 star property
Flores
10.0 out of 10, Exceptional, (347)
10/10
Exceptional
(347)
The price is $385
$385
$549 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Hotel Villa Maya
Hotel Villa Maya
3.0 star property
Flores
9.6 out of 10, Exceptional, (186)
9.6/10
Exceptional
(186)
Hotel Gringo Perdido
Hotel Gringo Perdido
1.5 star property
San Jose Peten
9.8 out of 10, Exceptional, (57)
9.8/10
Exceptional
(57)
The price is $114
$114
$188 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Posada del Cerro
Posada del Cerro
2.5 star property
Flores
9.4 out of 10, Exceptional, (8)
9.4/10
Exceptional
(8)
Hotel Camino Real Tikal
Hotel Camino Real Tikal
4.0 star property
San Jose Peten
8.8 out of 10, Excellent, (557)
8.8/10
Excellent
(557)
The price is $113
$113
$137 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Hotel & Brunch Lirio de los Valles
Hotel & Brunch Lirio de los Valles
3.0 star property
Flores
10.0 out of 10, Exceptional, (3)
10/10
Exceptional
(3)
The price is $41
$41
$50 total
includes taxes & fees
Jan 16 - Jan 17, 2026
Hotel Tiffany
Hotel Tiffany
3.0 star property
Flores
The price is $111
$111
$135 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Hotel Del Patio
Hotel Del Patio
3.0 star property
Flores
8.6 out of 10, Excellent, (336)
8.6/10
Excellent
(336)
The price is $54
$54
$66 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Posada Itza
Posada Itza
3.0 star property
Flores
10.0 out of 10, Exceptional, (1)
10/10
Exceptional
(1)
The price is $203
$203
$400 total
includes taxes & fees
Dec 28 - Dec 29
Hotel La Ribiera del Lago Peten Itza
Hotel La Ribiera del Lago Peten Itza
3.0 star property
San Jose Peten
4.8 out of 10, (14)
4.8/10
(14)
The price is $74
$74
$90 total
includes taxes & fees
Dec 28 - Dec 29
Hotel Tepeu
Hotel Tepeu
2.5 star property
Flores
9.2 out of 10, Wonderful, (102)
9.2/10
Wonderful
(102)
The price is $100
$100
$122 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Nakum Hotel
Nakum Hotel
2.0 star property
Flores
7.0 out of 10, Good, (4)
7.0/10
Good
(4)
The price is $41
$41
$50 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Hotel Maya Internacional
Hotel Maya Internacional
3.0 star property
Flores
7.8 out of 10, Good, (66)
7.8/10
Good
(66)
Peten Esplendido Hotel and Conference Center
Peten Esplendido Hotel and Conference Center
3.0 star property
Flores
7.6 out of 10, Good, (235)
7.6/10
Good
(235)
The price is $70
$70
$85 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Casa Ramona
Casa Ramona
3.0 star property
Flores
8.6 out of 10, Excellent, (33)
8.6/10
Excellent
(33)
The price is $50
$50
$93 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Hotel Casona del Lago
Hotel Casona del Lago
3.5 star property
Flores
9.0 out of 10, Wonderful, (295)
9.0/10
Wonderful
(295)
Isla de Flores Hotel
Isla de Flores Hotel
3.5 star property
Flores
9.4 out of 10, Exceptional, (464)
9.4/10
Exceptional
(464)
The price is $114
$114
$151 total
includes taxes & fees
Jan 16 - Jan 17, 2026
Hotel Casazul
Hotel Casazul
2.5 star property
Flores
8.8 out of 10, Excellent, (210)
8.8/10
Excellent
(210)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Santa Ana
Family friendly
Check out reviews of Santa Ana hotels guests love
Isla de Flores Hotel
10/10 Excellent
"Fantastic Hotel. Loved it. Clean, comfortable and stylish. Great location. Excellent restaurants and friendly staff. We will return."
Peten Esplendido Hotel and Conference Center
10/10 Excellent
"Our stay was perfect. An excelent choice for stay near Flores. The restaurant was delicious with a perfect view."
Bolontiku Boutique Hotel, Member of the Cayuga Collection
10/10 Excellent
"A beautiful boutique resort in a tranquil location. Very unique! "
Hotel Camino Real Tikal
10/10 Excellent
"The Hotel is beautiful, in the middle of nature, Clean, Staff super nice. Delicious food. Amazing"
Las Lagunas Boutique Hotel
10/10 Excellent
"Maybe…. The best hotel in Guatemala!"
Hotel Tepeu
10/10 Excellent
"Great hotel! Safe. Super friendly and accommodating staff. Couldn’t be happier. "
Hotel Villa Maya
10/10 Excellent
"Everything was good"
Hotel Casona del Lago
10/10 Excellent
"room was very clean, 24/7 front desk, good food, nice pool, felt very safe"
Hotel Villa del Lago
10/10 Excellent
"It was a cool spot. I would stay again. "
Frequently asked questions
Can I book a refundable hotel in Santa Ana?
If you want the flexibility to change your travel plans to Santa Ana, most properties offer refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in Santa Ana be like during my trip?
With an average temperature of 73°F during the coldest months, Santa Ana is a great place to visit any time of year.
Why should I book my Santa Ana hotel with Hotels.com?
There are lots of reasons to book your Santa Ana trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.