Hotels in Saint Louis

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Next weekend
In two weeks

Where to stay in Saint Louis?

Check out reviews of Saint Louis hotels guests love

Frequently asked questions

Can I book refundable accommodations in Saint Louis?
If you're looking for the flexibility to change your plans to Saint Louis, most properties provide refundable* bookable rates. You can see these properties by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in Saint Louis be like during my trip?
July and August are typically the warmest months in Saint Louis when the average temp is 65°F. December and February are the coldest months when the average temperature is 36°F. March and December are the months with the most rain.
Why should I book my Saint Louis accommodation with Hotels.com?
There are lots of reasons to book your Saint Louis trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.