Hotels in South Main
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Check prices for these dates
Tonight
Aug 11 - Aug 12Tomorrow
Aug 12 - Aug 13This weekend
Aug 14 - Aug 16Next weekend
Aug 21 - Aug 23Top 5 hotels in South Main at a glance
- Wyndham Houston near NRG Park/Medical Center — 3.5-star hotel in South Main. Guest rating: 7.2/10 — Good.
- Comfort Suites Houston near Medical Center- NRG Stadium — 2.5-star hotel in South Main. Guest rating: 8.8/10 — Excellent.
- Wingate Houston near NRG Park/Medical Center — 3-star hotel in South Main. Guest rating: 6.6/10.
- Quality Inn & Suites NRG Park - Medical Center — 2.5-star hotel in South Main. Guest rating: 6.6/10.
- Candlewood Suites Houston Medical Center by IHG — 2.5-star hotel in South Main. Guest rating: 7.4/10 — Good.
Where to stay in South Main?
Wyndham Houston near NRG Park/Medical Center
Wyndham Houston near NRG Park/Medical CenterSouth Main
Luis
$89
$104 total
includes taxes & fees
Aug 13 - Aug 14
Comfort Suites Houston near Medical Center- NRG Stadium
Comfort Suites Houston near Medical Center- NRG StadiumSouth Main
LaKeisha
$94
$110 total
includes taxes & fees
Sep 2 - Sep 3
Wingate Houston near NRG Park/Medical Center
Wingate Houston near NRG Park/Medical CenterSouth Main
Terry
$72
$84 total
includes taxes & fees
Aug 18 - Aug 19
Quality Inn & Suites NRG Park - Medical Center
Quality Inn & Suites NRG Park - Medical CenterSouth Main
HERBERT
$62
$73 total
includes taxes & fees
Aug 27 - Aug 28
Candlewood Suites Houston Medical Center by IHG
Candlewood Suites Houston Medical Center by IHGSouth Main
Barbara
$87
$102 total
includes taxes & fees
Sep 2 - Sep 3
Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG
Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG1.4 km from South Main
LINDSEY
$110
$130 total
includes taxes & fees
Aug 16 - Aug 17
Hyatt Place Houston Medical Center
Hyatt Place Houston Medical CenterTexas Medical Center, 3.1 km from South Main
Marcus
$125
$147 total
includes taxes & fees
Aug 16 - Aug 17
Hotel Ylem
Hotel Ylem2.3 km from South Main
Monica
$80
$98 total
includes taxes & fees
Aug 23 - Aug 24
Hyatt House Houston Medical Center
Hyatt House Houston Medical CenterTexas Medical Center, 3.1 km from South Main
estella
$121
$143 total
includes taxes & fees
Aug 27 - Aug 28
Blossom Hotel Houston, Curio Collection by Hilton
Blossom Hotel Houston, Curio Collection by HiltonTexas Medical Center, 3.5 km from South Main
Samantha
$147
$172 total
includes taxes & fees
Aug 21 - Aug 22
Hilton Houston Plaza/Medical Center
Hilton Houston Plaza/Medical CenterTexas Medical Center, 4.4 km from South Main
Gary
$89
$105 total
includes taxes & fees
Aug 30 - Aug 31
Hilton Garden Inn Houston Medical Center, TX
Hilton Garden Inn Houston Medical Center, TXTexas Medical Center, 4.7 km from South Main
Manuel
$106
$124 total
includes taxes & fees
Aug 20 - Aug 21
DoubleTree by Hilton Hotel Houston - Greenway Plaza
DoubleTree by Hilton Hotel Houston - Greenway PlazaGreenway Plaza-Upper Kirby, 6.6 km from South Main
CORRAHN
$81
$95 total
includes taxes & fees
Aug 21 - Aug 22
Best Western Plus Pearland/Houston Medical Center Hotel
Best Western Plus Pearland/Houston Medical Center HotelSoutheast Houston, 10.2 km from South Main
Sharon
$81
$95 total
includes taxes & fees
Aug 14 - Aug 15
The Westin Houston Medical Center/Museum District
The Westin Houston Medical Center/Museum DistrictTexas Medical Center, 4.4 km from South Main
Sheila
$152
$189 total
includes taxes & fees
Sep 6 - Sep 7
Home2 Suites by Hilton at the Galleria
Home2 Suites by Hilton at the GalleriaGreater Uptown, 8 km from South Main
Kevin
$106
$124 total
includes taxes & fees
Aug 18 - Aug 19
Studio 6 Houston, TX – Pearland/Medical Center
Studio 6 Houston, TX – Pearland/Medical CenterSoutheast Houston, 12.9 km from South Main
Pamela
$60
$70 total
includes taxes & fees
Aug 12 - Aug 13
Crowne Plaza Houston Med Ctr-Galleria Area by IHG
Crowne Plaza Houston Med Ctr-Galleria Area by IHGGreenway Plaza-Upper Kirby, 6.5 km from South Main
Margaret
$63
$74 total
includes taxes & fees
Aug 24 - Aug 25
Hotel Zaza Houston Museum District
Hotel Zaza Houston Museum District6.3 km from South Main
Stephanie
$244
$325 total
includes taxes & fees
Aug 12 - Aug 13
Holiday Inn Express & Suites Houston SW - Galleria Area by IHG
Holiday Inn Express & Suites Houston SW - Galleria Area by IHG9.6 km from South Main
odilia
$88
$103 total
includes taxes & fees
Aug 24 - Aug 25
Compare popular hotels in South Main
Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet friendly | WiFi included |
|---|---|---|---|---|---|---|---|
 Comfort Suites Houston near Medical Center- NRG Stadium | 8.8 Excellent 1,008 reviews | View | |||||
 Quality Inn & Suites NRG Park - Medical Center | 6.6 1,015 reviews | View | |||||
 Wyndham Houston near NRG Park/Medical Center | 7.2 Good 1,390 reviews | View | |||||
 Candlewood Suites Houston Medical Center by IHG | 7.4 Good 890 reviews | View | |||||
 Wingate Houston near NRG Park/Medical Center | 6.6 1,005 reviews | View |
Our prices for hotels in South Main are cheapest in August
Our prices for hotels in South Main are cheapest in August
Price trends for hotels in South Main
Pricing is based on two traveler single night rates
Check out reviews of South Main hotels guests love
The Royal Sonesta Houston Galleria
10/10 Excellent
"Great stay"
The Whitehall Houston
10/10 Excellent
"Room was clean and awesome bar experience"
Magnolia Hotel Houston, A Tribute Portfolio Hotel
8/10 Good
"Ok, check-in was a nightmare. I’m not blaming the receptionists but the process could have gone a little smoother. We were told our room was not ready at the 4:00 check-in time. We arrived shortly before 5:00 pm. We did not get into our room until 7:30. Two free drink tickets were received for our troubles. The drinks were gone by 6:00. An hour and a half later we were called and told our room was ready. It was not the room I reserved. After straightening things out at reception we finally get to our room. The rest of the stay was pleasant. If you ask to use the free shuttle that will only drive you within one mile of the hotel without cost, they acted very inconvenienced. No worries, we still used the shuttle and still tipped well. As for the breakfast, over $30 a plate for a pretty common but slightly upscale hotel continental breakfast. I will say the coffee was good, but the breakfast was 7 out of 10. If we stayed another night we’d have found another spot in downtown to eat. Overall, I think I would give another hotel in the downtown area a chance before booking here again. But if it were my last option, I guess I’d take it."
Grand Tuscany Hotel
10/10 Excellent
"Nice"
La Quinta Inn & Suites by Wyndham Houston Bush IAH South
8/10 Good
"Nice people could have been cleaner i was so glad they had a shuttle"
Hotel Zaza Houston Museum District
10/10 Excellent
"The Zaza is our home away from home anytime we wanna have a night or a weekend alone. This is the place we come to everyone’s friendly. It smells good. It has great vibes. The drinks and the food are always good. The shuttle service is pretty legit my favorite hotel in Houston by far."
Hilton Americas-Houston
10/10 Excellent
"Él hotel muy bonito, muy bien conservado, buena atención. Muy amables él staff, desde la puerta del hotel, front desk, camareras. El restaurant PAPASITOS muy bueno y acogedor. ."
Blossom Hotel Houston, Curio Collection by Hilton
10/10 Excellent
"I had a wonderful one-night stay at the Blossom Hotel Houston! The property itself is absolutely beautiful, with clean, stylish, and aesthetically pleasing rooms. The bed was incredibly comfortable, ensuring a great night's sleep. The staff were warm and welcoming, and the amenities really stand out—the rooftop pool and bar are gorgeous and offer fantastic views. I have zero complaints about my time here. Even for a short trip, the overall experience was top-tier, and I will definitely be returning next time I'm in Houston!"
Hyatt Regency Houston/Galleria
10/10 Excellent
"Great staff. Good location. Super clean."
Find out more about South Main