Hotels in La Mesa

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Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
Downtown San Diego
8.4 out of 10, Very Good, (6,294 reviews)
Wake to stunning bay views at this waterfront hotel near Port of San Diego. Hop on the trolley at America Plaza Station, just 7 minutes away, or enjoy lunch at Hazelwoods Bayside Deli. The outdoor pool offers a refreshing retreat after exploring nearby Petco Park.
The price is $152
$211 total
includes taxes & fees
Aug 3 - Aug 4
Wyndham San Diego Bayside

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection
3.0 star property
Downtown San Diego
8.8 out of 10, Excellent, (1,864 reviews)
Immerse yourself in San Diego's vibrant Little Italy at this Art Deco hotel. Take a dip in the outdoor pool, enjoy dinner at Ottutto, or grab drinks at the bar. Just 8 minutes from County Center station and a short drive to major attractions.
The price is $143
$166 total
includes taxes & fees
Aug 2 - Aug 3
The DEXTRO Little Italy, BW Premier Collection

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (4,031 reviews)
The price is $183
$261 total
includes taxes & fees
Jul 19 - Jul 20
Hard Rock Hotel San Diego

The Sofia Hotel

The Sofia Hotel
3.5 star property
Downtown San Diego
8.6 out of 10, Excellent, (2,372 reviews)
Unwind in the heart of San Diego at this historic hotel, just minutes from the convention center and Port. A 24-hour fitness center, on-site café, and room service enhance your stay. Within walking distance of USS Midway Museum and convenient transit options.
The price is $138
$187 total
includes taxes & fees
Aug 3 - Aug 4
The Sofia Hotel

California Suites Hotel

California Suites Hotel
2.0 star property
Clairemont
7.8 out of 10, Good, (2,718 reviews)
The price is $100
$115 total
includes taxes & fees
Jul 12 - Jul 13
California Suites Hotel

Handlery Hotel

Handlery Hotel
3.5 star property
Mission Valley
8.4 out of 10, Very Good, (2,720 reviews)
Experience a peaceful retreat with an outdoor pool, 2 restaurants, and poolside bar. Just 5 minutes from Mission Bay and steps to Fashion Valley Transit, you'll enjoy quiet surroundings while staying connected to San Diego Zoo and beach adventures.
The price is $153
$175 total
includes taxes & fees
Aug 2 - Aug 3
Handlery Hotel

Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (798 reviews)
Tucked into San Diego's Little Italy, this Courtyard boasts bay vistas and easy walks to local cafes. After exploring nearby Port of San Diego or USS Midway Museum, unwind at the outdoor pool or savor Mediterranean cuisine at Orexi.
The price is $175
$203 total
includes taxes & fees
Jul 19 - Jul 20
Courtyard by Marriott San Diego Downtown Little Italy

Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle
3.0 star property
Mission Valley
8.0 out of 10, Very Good, (2,905 reviews)
This San Diego hotel offers an outdoor pool and hot tub for relaxation after sightseeing. Located just minutes from San Diego Zoo and Balboa Park with Fashion Valley Transit Center a 13-minute walk away.
The price is $103
$118 total
includes taxes & fees
Aug 2 - Aug 3
Days Inn by Wyndham San Diego Hotel Circle

Best Western Seven Seas

Best Western Seven Seas
3.0 star property
Mission Valley
8.0 out of 10, Very Good, (3,713 reviews)
Tropical oasis near Fashion Valley Mall offers peaceful gardens and an outdoor pool with poolside bar. The Seven Seas Cafe serves meals all day, while 2 hot tubs provide relaxation. San Diego Zoo and Balboa Park are just minutes away.
The price is $123
$142 total
includes taxes & fees
Jul 27 - Jul 28
Best Western Seven Seas

Lafayette Hotel & Club

Lafayette Hotel & Club
4.0 star property
University Heights
9.4 out of 10, Exceptional, (1,801 reviews)
Splash into vacation at the outdoor pool or grab lunch at Quixote, one of 2 restaurants at this San Diego gem. With Balboa Park nearby and free WiFi throughout, you're perfectly placed for both work and play.
The price is $288
$331 total
includes taxes & fees
Jul 20 - Jul 21
Lafayette Hotel & Club

Bahia Resort Hotel

Bahia Resort Hotel
3.5 star property
Central Mission Beach
8.8 out of 10, Excellent, (2,247 reviews)
Set on Mission Beach with calm waters, this resort offers garden views and beautiful sunsets. Enjoy the outdoor pool, tennis courts, and hot tub after exploring nearby Mission Bay. The helpful staff ensures a serene atmosphere for a peaceful escape.
The price is $234
$324 total
includes taxes & fees
Aug 9 - Aug 10
Bahia Resort Hotel

Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
4.0 star property
Mission Valley
9.2 out of 10, Wonderful, (3,096 reviews)
Relax at this San Diego spa hotel just minutes from Old Town State Park. After enjoying the outdoor pool and poolside bar, recharge with deep-tissue massages and facials. The fitness center and coffee shop add convenience while nearby attractions await exploration.
The price is $249
$286 total
includes taxes & fees
Aug 2 - Aug 3
Legacy Resort Hotel & Spa

Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina
4.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (2,192 reviews)
The price is $236
$321 total
includes taxes & fees
Jul 30 - Jul 31
Marriott Marquis San Diego Marina

Kings Inn San Diego

Kings Inn San Diego
2.5 star property
Mission Valley
8.8 out of 10, Excellent, (3,757 reviews)
Soak up the sun at this quiet Art Deco hotel with 2 restaurants, including The Waffle Spot serving American cuisine. Located minutes from tourist hotspots, beaches, and Balboa Park, you'll enjoy the beautiful gardens and relaxing atmosphere.
The price is $143
$164 total
includes taxes & fees
Aug 11 - Aug 12
Kings Inn San Diego

Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark
4.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (2,294 reviews)
Immerse yourself in downtown San Diego at this welcoming hotel with an outdoor pool and poolside bar. Located minutes from the Convention Center and near public transit, this hotel offers massage services and a 24-hour fitness center for relaxation between adventures.
The price is $279
$369 total
includes taxes & fees
Jul 18 - Jul 19
Omni San Diego Hotel at the Ballpark

The Dana on Mission Bay

The Dana on Mission Bay
3.5 star property
Mission Bay
9.0 out of 10, Wonderful, (4,423 reviews)
Immerse yourself in coastal serenity at this Mission Bay hotel with stunning sunset vistas. Just minutes from Mission Beach, this haven offers 2 outdoor pools with poolside bars, plus a restaurant serving California cuisine. The marina location and garden landscapes create perfect vacation vibes.
The price is $259
$326 total
includes taxes & fees
Aug 9 - Aug 10
The Dana on Mission Bay

Hilton San Diego Bayfront

Hilton San Diego Bayfront
4.0 star property
Downtown San Diego
8.6 out of 10, Excellent, (2,227 reviews)
Luxurious retreat with an outdoor pool and poolside bar, just steps from Petco Park. Indulge in aromatherapy at the full-service spa, enjoy Californian cuisine at Hudson & Nash, and access the Gaslamp Quarter in 6 minutes.
The price is $234
$320 total
includes taxes & fees
Jul 19 - Jul 20
Hilton San Diego Bayfront

Paradise Point Resort & Spa

Paradise Point Resort & Spa
4.0 star property
Mission Bay
8.8 out of 10, Excellent, (2,731 reviews)
Discover a serene paradise with lush tropical gardens and easy beach access. Rent boats right from the marina, dine at the Californian cuisine restaurant, or unwind with deep-tissue massages at the spa. Mission Bay's treasures and Port of San Diego are just minutes away.
The price is $272
$365 total
includes taxes & fees
Aug 11 - Aug 12
Paradise Point Resort & Spa

The Horton Grand, Downtown/Gaslamp Quarter

The Horton Grand, Downtown/Gaslamp Quarter
3.5 star property
Downtown San Diego
9.2 out of 10, Wonderful, (2,878 reviews)
Immerse yourself in this beautifully preserved historic hotel with comfortable beds and a peaceful courtyard. Just minutes from the Convention Center, Seaport Village, and local cafes. Salt & Whiskey serves American cuisine after a day of nearby sightseeing.
The price is $158
$211 total
includes taxes & fees
Jul 19 - Jul 20
The Horton Grand, Downtown/Gaslamp Quarter

Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
3.5 star property
National City
9.2 out of 10, Wonderful, (3,939 reviews)
Unwind in American comfort at this National City hotel, just a short walk from 24th St Trolley Station. The outdoor pool provides cooling respite while Kimball's restaurant serves delicious meals. Free WiFi and convenient parking enhance your San Diego Bay adventure.
The price is $179
$197 total
includes taxes & fees
Jul 19 - Jul 20
Best Western Plus Marina Gateway Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

When is the best time to visit La Mesa?

Our prices for hotels in La Mesa are cheapest in January
Price trends for hotels in La Mesa
Pricing is based on two traveler single night rates
View properties in July
Currently viewing crowd sizes and weather for July.
Typical weather for La Mesa
July
High 28°C / low 19°C. Sunny most days.
View properties in July
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July, no crowd data, average high temperature 28 degrees Celsius, average low temperature 19 degrees Celsius. Sunny most days.
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August, no crowd data, average high temperature 29 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
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September, no crowd data, average high temperature 28 degrees Celsius, average low temperature 19 degrees Celsius. Sunny most days.
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October, no crowd data, average high temperature 26 degrees Celsius, average low temperature 16 degrees Celsius. Sunny most days.
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November, no crowd data, average high temperature 22 degrees Celsius, average low temperature 13 degrees Celsius. Sunny most days.
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December, no crowd data, average high temperature 18 degrees Celsius, average low temperature 10 degrees Celsius. Sunny most days.
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January, no crowd data, average high temperature 19 degrees Celsius, average low temperature 10 degrees Celsius. Sunny most days.
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February, no crowd data, average high temperature 19 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
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March, no crowd data, average high temperature 20 degrees Celsius, average low temperature 10 degrees Celsius. Sunny most days.
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April, no crowd data, average high temperature 21 degrees Celsius, average low temperature 12 degrees Celsius. Sunny most days.
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May, no crowd data, average high temperature 22 degrees Celsius, average low temperature 13 degrees Celsius. Sunny most days.
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June, no crowd data, average high temperature 25 degrees Celsius, average low temperature 16 degrees Celsius. Sunny most days.
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Monthly weather averages (˚C)

Top neighborhoods in La Mesa

Casa de Oro-Mount Helix

La Mesa's Casa de Oro-Mount Helix neighborhood offers attractions including Mount Helix Park.

Mount Helix

The Mount Helix neighborhood offers attractions such as Mount Helix Park and FAITH CHAPEL.

Top landmarks in La Mesa

Learn more about La Mesa

Between the bustle of San Diego and the quiet of the hills, La Mesa lives up to its 'Jewel of the Hills' nickname without trying too hard. The historic Village area offers boutiques and cafés where locals actually eat, not just places that survive on tourist traffic. Mount Helix rewards a short climb with panoramic views that explain why everyone in California seems suspiciously content. Lake Murray Park provides a refreshing escape where fishing lines dangle alongside kayakers who've discovered this urban oasis. Train enthusiasts find unexpected delight at the Pacific Southwest Railway Museum, where vintage locomotives sit frozen in time.

A sunset over a mountainous landscape with scattered clouds.

Check out reviews of La Mesa hotels guests love

Frequently asked questions

What accommodations do travelers like in La Mesa?
Can I book a refundable accommodation in La Mesa?
If you need the flexibility to change your travel plans to La Mesa, most hotels offer refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in La Mesa if I want a vacation home instead of a hotel?
If you're looking for a good alternative to a hotel, review our selection of 68 vacation homes. In addition, you can choose from 7 apartments.
What will the weather in La Mesa be like during my trip?
August and September are typically the warmest months in La Mesa when the average temp is 72°F. February and January are the coldest months when the average temperature is 56°F. December and February are the months with the most rain.
Why should I book my La Mesa hotel through Hotels.com?
There are lots of reasons to book your La Mesa trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.