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Hotels in Anna

September 2026
11
October 2026

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This weekend
Sep 11 - Sep 13
Next weekend
Sep 18 - Sep 20

Where to stay in Anna?

An indoor swimming pool with clear water, marked lanes, and a lifeguard warning sign.
A modern living room with two sofas, a coffee table, and a TV.
A dining area with wooden flooring, red upholstered chairs, and a mural of a pyramid.
A hotel room with a treadmill, exercise bike, and dumbbells.

1. Hotel 7 Inn Anna

Hotel 7 Inn Anna
Anna
$85
$98 total
includes taxes & fees
Sep 13 - Sep 14
Hotel 7 Inn Anna
A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.
An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.
A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.

2. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
$100
$113 total
includes taxes & fees
Sep 20 - Sep 21
Drury Plaza Hotel Cape Girardeau Conference Center
A spacious lobby with a curved staircase, large windows, and a seating area with a rug.
A modern outdoor seating area with a glass-top table and a fire feature, overlooking a sunset view.
A modern bar area with a herringbone patterned wall, a long counter with bar stools, and a variety of bottles and glasses.
A hotel room with two beds, a desk, a chair, and a view of the city.

3. The Riverview

The Riverview
Cape Girardeau
$114
$129 total
includes taxes & fees
Sep 13 - Sep 14
The Riverview
A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.
An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.
A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.
A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.

4. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
$101
$115 total
includes taxes & fees
Sep 20 - Sep 21
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
A hotel room with a large bed, two bedside tables with lamps, a window with curtains, a painting on the wall, and a radiator.
A small kitchen area with a coffee machine, a trash bin, and a potted plant.
A hotel room with a television on a wooden cabinet, a floor lamp, a green sofa, and a small table.
A building with a sign reading "Lake Tree Inn & Suites" and a picnic table in front.

5. Laketree Inn And Suites Marion

Laketree Inn And Suites Marion
Marion
$80
$89 total
includes taxes & fees
Sep 13 - Sep 14
Laketree Inn And Suites Marion
A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.
A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.
A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.
A Dear Tree Inn building with a covered entrance and a clear sky at dusk.

6. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
Cape Girardeau
$72
$81 total
includes taxes & fees
Sep 20 - Sep 21
Pear Tree Inn Cape Girardeau West
A hotel entrance with a 'Welcome' sign and a 'Hampton Inn' sign.
A reception area with a reception desk, a waiting area with a patterned armchair, and a reception counter with a computer and framed pictures.
A lobby with a patterned carpet, a yellow armchair, a glass door entrance, and shelves stocked with snacks and beverages.
A hotel dining area with multiple tables and chairs, a bar, and a sofa.

7. Hampton Inn Carbondale

Hampton Inn Carbondale
Carbondale
$105
$121 total
includes taxes & fees
Sep 13 - Sep 14
Hampton Inn Carbondale
A spacious lobby with marble flooring, elegant seating, and a grand staircase.
A spacious living room with a sofa set, a coffee table, and a dining area.
A lobby with seating areas, a reception desk, and a bar.
A modern hotel lobby with a framed advertisement for breakfast at the new Bistro, a seating area with sofas and a coffee table, and a decorative mirror reflecting the space.

8. Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
Cape Girardeau
$125
$142 total
includes taxes & fees
Sep 20 - Sep 21
Courtyard by Marriott Cape Girardeau Downtown
A rustic lodge with a steeply pitched roof, a central entrance with a door, and a porch with multiple lights.
A stone building with a patio area, string lights, and outdoor seating.
A cozy living room with a brown leather sofa, a wooden coffee table, and a window with a view of trees.
A cozy log cabin interior with a wooden staircase, a cushioned sofa, a small table, and a lamp.

9. Makanda Inn

Makanda Inn
Makanda
$262
$299 total
includes taxes & fees
Sep 13 - Sep 14
Makanda Inn
A spacious lobby with high ceilings, multiple seating areas, and large windows allowing natural light.
An outdoor patio area with a table and chairs, a red umbrella, and a brick building facade.
An indoor swimming pool with clear water, tiled walls, and a ceiling with square vents.

10. Drury Inn & Suites Marion

Drury Inn & Suites Marion
Marion
$94
$113 total
includes taxes & fees
Sep 20 - Sep 21
Drury Inn & Suites Marion
A modern retail area with a display of local items and snacks.
A hotel room with two beds, a desk, a chair, a TV, and a window with a view.
A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.
A modern indoor seating area with blue sofas and tables, a patterned carpet, and large windows offering a view of the outdoors.

11. Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
Cape Girardeau
$89
$102 total
includes taxes & fees
Sep 20 - Sep 21
Tru By Hilton Cape Girardeau
A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.
A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.
A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.
A reception area with a wooden reception desk, a glass door leading to a storage room, and a decorative wall piece.

12. Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
Cape Girardeau
$101
$114 total
includes taxes & fees
Sep 20 - Sep 21
Fairfield Inn & Suites by Marriott Cape Girardeau
A hotel room with two beds, a desk, a chair, a TV, a lamp, and a painting on the wall.
A bar area with multiple stools, a bar counter, shelves of liquor bottles, and hanging pendant lights.
A modern restaurant with a bar area, multiple tables and chairs, and a kitchen in the background.
A modern hotel lobby with leather sofas, a flat-screen TV, and framed artwork on the walls.

13. Best Western Saluki Inn

Best Western Saluki Inn
Carbondale
$90
$105 total
includes taxes & fees
Sep 27 - Sep 28
Best Western Saluki Inn
A room with a brown sofa, a brown armchair, a patterned carpet, a lamp, and a window with curtains.
A hotel lobby with a reception desk, several tables and chairs, framed pictures on the walls, and a clock.
A hotel room with a microwave, refrigerator, chair, and a window with curtains.
A hotel with a Super 8 sign, multiple parking spaces, and a brick facade.

14. Super 8 by Wyndham Carbondale

Super 8 by Wyndham Carbondale
Carbondale
$65
$75 total
includes taxes & fees
Sep 13 - Sep 14
Super 8 by Wyndham Carbondale
A hotel room with two beds, a desk, a chair, a TV, and a projector screen.
A coffee station with two espresso machines, a coffee press, and various coffee cups and containers.
A conference room with tables, chairs, a flat-screen TV, and a sign indicating amenities.
A reception area with two reception desks, a wall-mounted sign, and a refrigerator.

15. Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
Murphysboro
$122
$135 total
includes taxes & fees
Sep 28 - Sep 29
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
A spacious dining area with high ceilings, large windows, and modern lighting fixtures.
An outdoor patio with stone walls, wicker furniture, and large windows.
A gym with exercise equipment, a treadmill, and a wall-mounted TV.
A hotel room with a bed, a desk with a television, a chair, a suitcase, and a map on the wall.

16. Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
Cape Girardeau
$106
$119 total
includes taxes & fees
Sep 20 - Sep 21
Hampton Inn Cape Girardeau I 55 East
An outdoor patio with stone fire pit, colorful striped sofas, and blue chairs.
A spacious lobby with a central seating area, a large window, and a reception desk.
A hotel reception area with a wooden reception desk, a digital kiosk, and a refrigerated display case with beverages.
A modern kitchen with a stainless steel refrigerator, microwave, and dishwasher. There is a window providing natural light and a view of the outdoors.

17. Home2 Suites by Hilton Carbondale

Home2 Suites by Hilton Carbondale
Carbondale
$120
$138 total
includes taxes & fees
Sep 28 - Sep 29
Home2 Suites by Hilton Carbondale
A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.
A hotel room with a flat-screen TV, a microwave, a sofa, a lamp, and a window with curtains.
A hotel room with a large bathtub, a bed with a wooden headboard, a nightstand with a lamp, and a painting of a building on the wall.
A restaurant with multiple tables and chairs, an exit sign, a television, and a counter with food items.

18. Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
Cape Girardeau
$59
$67 total
includes taxes & fees
Sep 20 - Sep 21
Quality Inn Cape Girardeau North
A building entrance with a bench, potted plants, and a door marked "709".
An indoor swimming pool with clear blue water, surrounded by lounge chairs and a tiled wall.
A white pickup truck parked under a covered area with a bench and potted plants nearby.
Two slot machines with a J&J Gaming logo, a television above the left machine, and a chair in front.

19. Hotel 7 Vienna

Hotel 7 Vienna
Vienna
$75
$84 total
includes taxes & fees
Oct 1 - Oct 2
Hotel 7 Vienna
A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.
A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.
A bowl of cereal with raisins and milk, a half orange, and a sandwich on a table with a yellow napkin.
A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.

20. Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
Cape Girardeau
$90
$102 total
includes taxes & fees
Sep 20 - Sep 21
Drury Inn & Suites Cape Girardeau
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Go beyond your typical stay in Anna

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Spa
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Our prices for hotels in Anna are cheapest in September

Price trends for hotels in Anna

Pricing is based on two traveler single night rates
View properties in September

September

High 27°C / low 17°C. Sunny most days.
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Monthly weather averages (˚C)

Top landmarks in Anna

Anna City Park

8.8/10 (8 reviews)
Anna City Park is 0.3 mi (0.5 km) from central Anna, why not stop by during your stay.
See properties

King Neptune Memorial

If you're planning a bit of sightseeing during your trip, head to King Neptune Memorial— just one of the landmarks located 6.3 mi (10.1 km) from central Anna.
See properties

Learn more about Anna

Anna is well-known for its attractions such as Shawnee National Forest and Anna City Park. The city has something for everyone including sights like King Neptune Memorial within a rural setting.

See all hotels in Anna
A coastal town with clear turquoise waters, rocky shores, and white buildings.

Check out reviews of Anna hotels guests love

A hotel room with two beds, a desk, a chair, a TV, and a projector screen.
A coffee station with two espresso machines, a coffee press, and various coffee cups and containers.
A conference room with tables, chairs, a flat-screen TV, and a sign indicating amenities.
A reception area with two reception desks, a wall-mounted sign, and a refrigerator.

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
Murphysboro

10/10 Exceptional

United States
Sharra
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
A modern living room with a fireplace, a bookshelf, a large wall clock, and a cozy seating area.
A Country Inn & Suites building with a covered entrance and a parking lot.
An indoor swimming pool with clear water, surrounded by white lounge chairs and tables, with a high ceiling and natural light from windows.
A reception area with a wooden counter, a welcome mat, and framed artwork on the wall.

Country Inn & Suites by Radisson, Marion, IL

Country Inn & Suites by Radisson, Marion, IL
Marion

10/10 Exceptional

United States
Beth
Country Inn & Suites by Radisson, Marion, IL
A room with a brown sofa, a brown armchair, a patterned carpet, a lamp, and a window with curtains.
A hotel lobby with a reception desk, several tables and chairs, framed pictures on the walls, and a clock.
A hotel room with a microwave, refrigerator, chair, and a window with curtains.
A hotel with a Super 8 sign, multiple parking spaces, and a brick facade.

Super 8 by Wyndham Carbondale

Super 8 by Wyndham Carbondale
Carbondale

10/10 Exceptional

United States
Anonymous traveler
Super 8 by Wyndham Carbondale
A hotel room with a bed, a desk, a dresser, a mirror, and a nightstand with a lamp.
A compact hotel room with a kitchenette, a single bed, a desk with a chair, a TV, and a window with curtains.
A reception area with a wooden counter, a clock, and a door leading outside.
A building with a brick facade, a covered entrance with glass doors, and a clear sky.

Motel 6 Marion, IL

Motel 6 Marion, IL
Marion

10/10 Exceptional

United States
Anonymous traveler
Motel 6 Marion, IL
A hotel lobby with wooden beams, a reception desk, a coffee machine, and a display of food items.
A dining area with wooden tables and chairs, a TV mounted on the wall, and a kitchen area with wooden cabinets and a countertop.
A courtyard with a swimming pool, outdoor seating, and a building with multiple windows and arches.
A hotel room with a large bed, a desk with a lamp, a chair, an air conditioning unit, and a television.

Quality Inn & Suites Marion

Quality Inn & Suites Marion
Marion

10/10 Exceptional

United States
Sanford
Quality Inn & Suites Marion
A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.
An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.
A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau

10/10 Exceptional

United States
Janet
Drury Plaza Hotel Cape Girardeau Conference Center
A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.
An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.
A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.
A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau

10/10 Exceptional

United States
David
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
A spacious lobby with high ceilings, multiple seating areas, and large windows allowing natural light.
An outdoor patio area with a table and chairs, a red umbrella, and a brick building facade.
An indoor swimming pool with clear water, tiled walls, and a ceiling with square vents.

Drury Inn & Suites Marion

Drury Inn & Suites Marion
Marion

10/10 Exceptional

United States
Dorothy
Drury Inn & Suites Marion
A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.
A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.
A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.
A Dear Tree Inn building with a covered entrance and a clear sky at dusk.

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
Cape Girardeau

10/10 Exceptional

United States
Kimberly
Pear Tree Inn Cape Girardeau West
A spacious lobby with a curved staircase, large windows, and a seating area with a rug.
A modern outdoor seating area with a glass-top table and a fire feature, overlooking a sunset view.
A modern bar area with a herringbone patterned wall, a long counter with bar stools, and a variety of bottles and glasses.
A hotel room with two beds, a desk, a chair, and a view of the city.

The Riverview

The Riverview
Cape Girardeau

10/10 Exceptional

United States
Mark
The Riverview
A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.
A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.
A bowl of cereal with raisins and milk, a half orange, and a sandwich on a table with a yellow napkin.
A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
Cape Girardeau

10/10 Exceptional

United States
StephM
Drury Inn & Suites Cape Girardeau
A spacious dining area with high ceilings, large windows, and modern lighting fixtures.
An outdoor patio with stone walls, wicker furniture, and large windows.
A gym with exercise equipment, a treadmill, and a wall-mounted TV.
A hotel room with a bed, a desk with a television, a chair, a suitcase, and a map on the wall.

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
Cape Girardeau

10/10 Exceptional

United States
Reese
Hampton Inn Cape Girardeau I 55 East
A hotel entrance with a 'Welcome' sign and a 'Hampton Inn' sign.
A reception area with a reception desk, a waiting area with a patterned armchair, and a reception counter with a computer and framed pictures.
A lobby with a patterned carpet, a yellow armchair, a glass door entrance, and shelves stocked with snacks and beverages.
A hotel dining area with multiple tables and chairs, a bar, and a sofa.

Hampton Inn Carbondale

Hampton Inn Carbondale
Carbondale

10/10 Exceptional

United States
John
Hampton Inn Carbondale
A modern breakfast bar with a coffee machine, cereal, and fruit display.
A coffee station with multiple coffee dispensers, a hot water station, and a variety of coffee products on display.
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.
An indoor swimming pool with a tiled edge, a metal ladder, and several lounge chairs.

Holiday Inn Express Hotel & Suites Marion Northeast by IHG

Holiday Inn Express Hotel & Suites Marion Northeast by IHG
Marion

10/10 Exceptional

United States
Justin
Holiday Inn Express Hotel & Suites Marion Northeast by IHG
A self-service breakfast area with a coffee machine, refrigerated display case, and various food items.
A hotel room with a bed, a television, a desk, a coffee machine, and a bathroom visible through an open door.
A spacious lobby with a sofa, chairs, a coffee table, and a dining area with tables and chairs.
A Best Western hotel with a parking lot and a covered entrance.

Best Western Marion Hotel

Best Western Marion Hotel
Marion

10/10 Exceptional

United States
Alice
Best Western Marion Hotel
A modern retail area with a display of local items and snacks.
A hotel room with two beds, a desk, a chair, a TV, and a window with a view.
A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.
A modern indoor seating area with blue sofas and tables, a patterned carpet, and large windows offering a view of the outdoors.

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
Cape Girardeau

10/10 Exceptional

United States
James
Tru By Hilton Cape Girardeau

Frequently Asked Questions

What accommodations do travelers like in Anna?

Guests like Hotel 7 Inn Anna.

Can I book a refundable hotel in Anna?

If you want the flexibility to change your travel plans to Anna, most properties offer refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.

Where can I stay in Anna if I want a budget-friendly accommodation?

An inexpensive option worth considering is Hotel 7 Inn Anna.

Where can I stay in Anna if I want a vacation rental instead of a traditional hotel?

If you're looking for a good alternative to a hotel, browse our selection of 7 vacation homes. You can also book one of the 6 cabins for your stay.

What will the weather in Anna be like during my vacation?

The warmest months in Anna are usually July and August with an average temp of 75°F. January and February are the chilliest months when the average temp is 39°F. The rainiest months are April and March.

Why should I book my Anna accommodation with Hotels.com?

There are plenty of reasons to book your Anna travel with us: our free cancellations on selected hotels* gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.