Hotels in St. Charles

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Super 8 by Wyndham St Charles
Super 8 by Wyndham St Charles
2.0 star property
St. Charles
8.0 out of 10, Very Good, (1,004 reviews)
Wake up to a serene stay and complimentary morning meal at this quiet St. Charles retreat. Just minutes from Ameristar Casino and Cave Spring Golf Center, this hotel offers free WiFi, parking, and clean rooms with attentive staff to ensure comfort.
The price is $93
$106 total
includes taxes & fees
Apr 21 - Apr 22
Super 8 by Wyndham St Charles
Hampton Inn St. Charles St. Peters
Hampton Inn St. Charles St. Peters
2.5 star property
St. Charles
8.0 out of 10, Very Good, (1,001 reviews)
Near the excitement of Ameristar Casino, this welcoming hotel provides an indoor pool for swimming anytime. Enjoy a complimentary breakfast, free WiFi, and parking, while the 24-hour fitness center keeps your workout routine intact during travels.
The price is $114
$131 total
includes taxes & fees
Apr 26 - Apr 27
Hampton Inn St. Charles St. Peters
Comfort Suites St Charles - St Louis
Comfort Suites St Charles - St Louis
2.5 star property
St. Charles
8.4 out of 10, Very Good, (1,013 reviews)
Wake up to a riverside retreat minutes from Ameristar Casino. This hotel offers free breakfast, WiFi, and parking, plus an indoor pool for year-round relaxation. Guests praise the attentive staff and spotless rooms near Lewis & Clark Boathouse.
The price is $88
$102 total
includes taxes & fees
May 10 - May 11
Comfort Suites St Charles - St Louis
Americas Best Value Inn & Suites St. Louis, St. Charles Inn
Americas Best Value Inn & Suites St. Louis, St. Charles Inn
2.5 star property
St. Charles
5.6 out of 10, (1,004 reviews)
This convenient hotel boasts free breakfast, WiFi, and parking minutes from the Ameristar Casino. Guests can maintain routines at the fitness center before exploring nearby restaurants and attractions. St. Louis Lambert Airport is just 11 minutes away.
The price is $90
$104 total
includes taxes & fees
Apr 16 - Apr 17
Americas Best Value Inn & Suites St. Louis, St. Charles Inn
Relax Inn Saint Charles
Relax Inn Saint Charles
2.0 star property
St. Charles
6.8 out of 10, (1,002 reviews)
Convenient St. Charles location offering free WiFi and parking, with Ameristar Casino and Cave Spring Golf Center nearby. Clean, comfortable rooms provide a practical base for exploring local attractions while staying on budget.
The price is $63
$72 total
includes taxes & fees
Apr 25 - Apr 26
Relax Inn Saint Charles
Country Inn & Suites by Radisson, St. Peters, MO
Country Inn & Suites by Radisson, St. Peters, MO
2.5 star property
St. Charles
8.0 out of 10, Very Good, (1,007 reviews)
Conveniently located within a 10-minute drive of Ameristar Casino, this St. Charles hotel offers an indoor pool for year-round swimming. Enjoy free breakfast, WiFi, and parking while exploring nearby attractions. Clean rooms and helpful staff enhance your stay.
The price is $85
$97 total
includes taxes & fees
May 10 - May 11
Country Inn & Suites by Radisson, St. Peters, MO
Holiday Inn Express Hotel and Suites St. Charles by IHG
Holiday Inn Express Hotel and Suites St. Charles by IHG
3.0 star property
St. Charles
8.2 out of 10, Very Good, (729 reviews)
Located in St. Charles, this hotel puts you 15 minutes from Hollywood Casino Amphitheatre and Ameristar Casino. Enjoy Sugarfire BBQ Restaurant's tasty barbecue, plus convenient perks like free breakfast, WiFi, and parking. Nearby Jaycee Park offers outdoor recreation.
The price is $127
$146 total
includes taxes & fees
Apr 26 - Apr 27
Holiday Inn Express Hotel and Suites St. Charles by IHG
Sleep Inn Saint Charles North
Sleep Inn Saint Charles North
2.5 star property
St. Charles
5.8 out of 10, (529 reviews)
Splash into the indoor pool at this St. Charles hotel offering complimentary WiFi, buffet breakfast, and parking. Located within 15 minutes of Ameristar Casino and near Jaycee Park, the convenient access to St. Louis Lambert Airport makes this a practical choice.
The price is $74
$85 total
includes taxes & fees
May 10 - May 11
Sleep Inn Saint Charles North
Drury Plaza Hotel St. Louis St. Charles
Drury Plaza Hotel St. Louis St. Charles
3.0 star property
St. Charles
9.6 out of 10, Exceptional, (1,000 reviews)
Splash into fun at this riverside hotel with dual swimming options, a relaxing hot tub, and complimentary breakfast. Just minutes from Lewis & Clark Boathouse and a short walk to gaming entertainment, all while enjoying free WiFi and parking.
The price is $132
$153 total
includes taxes & fees
May 3 - May 4
Drury Plaza Hotel St. Louis St. Charles
Tru by Hilton St. Charles St. Louis, MO
Tru by Hilton St. Charles St. Louis, MO
2.5 star property
St. Charles
8.6 out of 10, Excellent, (816 reviews)
Just 5 minutes from Ameristar Casino, this St. Charles hotel offers a fitness center and daily continental breakfast. Guests appreciate the helpful staff, convenient location near Lewis & Clark Boathouse, and complimentary WiFi and parking.
The price is $114
$132 total
includes taxes & fees
Apr 26 - Apr 27
Tru by Hilton St. Charles St. Louis, MO
Ameristar Casino Resort and Spa
Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.4 out of 10, Very Good, (1,000 reviews)
Elevate your stay at this luxurious St. Charles casino resort featuring 6 restaurants including Bugattis Steak and Pasta. Unwind with massages at the full-service spa, enjoy the outdoor pool with a poolside bar, or try your luck at the on-site casino.
The price is $179
$226 total
includes taxes & fees
Apr 26 - Apr 27
Ameristar Casino Resort and Spa
Candlewood Suites St Louis St Charles by IHG
Candlewood Suites St Louis St Charles by IHG
2.5 star property
St. Charles
7.6 out of 10, Good, (795 reviews)
This hotel offers easy access to Ameristar Casino and Cave Spring Golf Center, with free WiFi and parking. The 24-hour fitness center provides workout convenience, while the helpful staff ensures a comfortable stay near St. Louis attractions.
The price is $84
$97 total
includes taxes & fees
Apr 26 - Apr 27
Candlewood Suites St Louis St Charles by IHG
Hampton Inn & Suites St. Charles Old Town Area
Hampton Inn & Suites St. Charles Old Town Area
2.5 star property
St. Charles
9.0 out of 10, Wonderful, (680 reviews)
Steps from Lewis & Clark Boathouse and a short drive to Ameristar Casino, this welcoming hotel offers an indoor pool, 24-hour fitness center, and complimentary breakfast. Guests rave about the helpful staff and free parking.
The price is $139
$166 total
includes taxes & fees
May 3 - May 4
Hampton Inn & Suites St. Charles Old Town Area
WoodSpring Suites St Louis St Charles
WoodSpring Suites St Louis St Charles
2.5 star property
St. Charles
5.4 out of 10, (298 reviews)
Strategically positioned for quick drives to Ameristar Casino and Family Arena, this practical hotel offers free WiFi and parking. Guests appreciate the business-friendly atmosphere, convenient laundry facilities, and easy access to St. Louis Lambert International Airport.
The price is $80
$92 total
includes taxes & fees
Apr 16 - Apr 17
WoodSpring Suites St Louis St Charles
Embassy Suites by Hilton St. Louis St. Charles
Embassy Suites by Hilton St. Louis St. Charles
3.5 star property
St. Charles
8.6 out of 10, Excellent, (1,000 reviews)
Experience peaceful comfort at this St. Charles hotel, surprisingly quiet even when full of children. Minutes from Lewis & Clark Boathouse, with free parking and breakfast that guests love. The helpful staff and nearby restaurants create a perfect base for casino visits.
The price is $147
$169 total
includes taxes & fees
May 3 - May 4
Embassy Suites by Hilton St. Louis St. Charles
Country Inn & Suites by Radisson, St. Charles Historic District
Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
St. Charles Historic District
9.4 out of 10, Exceptional, (1,005 reviews)
Escape to this charming retreat steps from Ameristar Casino. Start your day with a delicious free breakfast, swim in the indoor pool, then explore nearby Lewis & Clark Boathouse. Return to comfy rooms with free WiFi after strolling the historic district.
The price is $131
$150 total
includes taxes & fees
May 10 - May 11
Country Inn & Suites by Radisson, St. Charles Historic District
Holiday Inn Express & Suites Edwardsville by IHG
Holiday Inn Express & Suites Edwardsville by IHG
2.5 star property
Edwardsville
9.2 out of 10, Wonderful, (859 reviews)
Travelers love this hotel's courteous staff and pristine condition. Recharge with a free breakfast before exploring nearby attractions, or swim year-round in the indoor pool. The fitness center, free WiFi and parking enhance your Edwardsville visit.
The price is $144
$166 total
includes taxes & fees
Apr 19 - Apr 20
Holiday Inn Express & Suites Edwardsville by IHG
Country Hearth Inn & Suites Edwardsville St. Louis
Country Hearth Inn & Suites Edwardsville St. Louis
2.5 star property
Edwardsville
8.6 out of 10, Excellent, (690 reviews)
Enjoy this welcoming hotel near Edwardsville Arts Center where hiking paths await your exploration. The fitness center keeps you active while free breakfast, WiFi, and parking add extra value to your stay. Friendly staff receive consistent praise from visitors.
The price is $139
$160 total
includes taxes & fees
Apr 16 - Apr 17
Country Hearth Inn & Suites Edwardsville St. Louis
Comfort Inn Edwardsville - St. Louis
Comfort Inn Edwardsville - St. Louis
2.5 star property
Edwardsville
8.4 out of 10, Very Good, (837 reviews)
Dive into the indoor pool or energize at the 24-hour fitness center after exploring nearby Vadalabene Center. Free breakfast, WiFi, and parking enhance your stay while the notably helpful staff ensures comfort in this quiet, central location.
The price is $103
$119 total
includes taxes & fees
May 5 - May 6
Comfort Inn Edwardsville - St. Louis
Casino Queen Hotel
Casino Queen Hotel
3.0 star property
East St. Louis
7.6 out of 10, Good, (2,049 reviews)
Escape to a tranquil hotel near downtown St. Louis, steps from East Riverfront Station. Enjoy breathtaking Gateway Arch vistas, try your luck at the casino, or splash in the indoor pool. Clean rooms, helpful staff, and free WiFi make for a memorable stay.
The price is $84
$98 total
includes taxes & fees
Apr 16 - Apr 17
Casino Queen Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Check out family-friendly hotels in St. Charles

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

When is the best time to visit St. Charles?

Our prices for hotels in St. Charles are cheapest in January
Price trends for hotels in St. Charles
Pricing is based on two traveler single night rates
View properties in April
Currently viewing crowd sizes and weather for April.
Typical weather for St. Charles
April
High 18°C / low 8°C. Sunny most days.
View properties in April
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April, no crowd data, average high temperature 18 degrees Celsius, average low temperature 8 degrees Celsius. Sunny most days.
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May, no crowd data, average high temperature 24 degrees Celsius, average low temperature 14 degrees Celsius. Sunny most days.
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June, no crowd data, average high temperature 29 degrees Celsius, average low temperature 19 degrees Celsius. Sunny most days.
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July, no crowd data, average high temperature 31 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
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August, no crowd data, average high temperature 30 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
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September, no crowd data, average high temperature 27 degrees Celsius, average low temperature 16 degrees Celsius. Sunny most days.
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October, no crowd data, average high temperature 20 degrees Celsius, average low temperature 10 degrees Celsius. Sunny most days.
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November, no crowd data, average high temperature 13 degrees Celsius, average low temperature 3 degrees Celsius. Partly sunny.
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December, no crowd data, average high temperature 7 degrees Celsius, average low temperature -1 degrees Celsius. Partly sunny.
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January, no crowd data, average high temperature 4 degrees Celsius, average low temperature -4 degrees Celsius. Cloudy most days.
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February, no crowd data, average high temperature 6 degrees Celsius, average low temperature -3 degrees Celsius. Partly sunny.
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March, no crowd data, average high temperature 13 degrees Celsius, average low temperature 3 degrees Celsius. Partly sunny.
Monthly weather averages (˚C)

Top neighborhoods in St. Charles

St. Charles Historic District

Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.

Top landmarks in St. Charles

Learn more about St. Charles

Wander cobblestone streets on historic Main Street, where gas lamps illuminate shops selling everything from handcrafted jewelry to homemade fudge. The Lewis and Clark Boathouse offers a fascinating glimpse into the explorers' journey that began right here in 1804. Pedal along the Katy Trail, where the former railroad track hugs the Missouri River with views that explain why those French-Canadian fur traders settled here in the first place. The restored buildings house restaurants where locals debate which has the best bread pudding (they're all correct). At the riverfront, watch barges navigate the same waters that launched America's westward expansion. History feels remarkably present here, as if those early pioneers might stroll around the corner at any moment.

The historic 18th century Main Street through the brick paved old town of St. Charles, Missouri, along the Missouri River.

Check out reviews of St. Charles hotels guests love

Frequently asked questions

What accommodations do travelers like in St. Charles?
Can I book a refundable accommodation in St. Charles?
If you need the flexibility to change your plans to St. Charles, most properties provide refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in St. Charles if I want a vacation rental instead of a hotel?
If you want a good alternative to a hotel, review our selection of 86 vacation homes. You can also consider one of the 41 apartments or 8 cottages.
What will the weather in St. Charles be like during my vacation?
July and August are typically the warmest months in St. Charles when the average temp is 75°F. January and February are the coldest months when the average temperature is 37°F. May and April are the months with the most rain.
Why should I book my St. Charles hotel through Hotels.com?
There are lots of reasons to book your St. Charles trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.