Hotels in Charleston

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight
May 11 - May 12
Tomorrow
May 12 - May 13
This weekend
May 15 - May 17
Next weekend
May 22 - May 24

Where to stay in Charleston?

Lobby sitting area
The Riverstone Hotel Charleston-Sikeston
The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (412 reviews)
The price is $75
$83 total
includes taxes & fees
May 12 - May 13
The Riverstone Hotel Charleston-Sikeston
Laptop workspace, blackout drapes, free cribs/infant beds, free WiFi
Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.8 out of 10, (632 reviews)
This Charleston motel offers complimentary WiFi, parking, and on-the-go breakfast daily. Located with convenient interstate access to Cape Girardeau, guests consistently praise the helpful staff. The comfortable accommodations provide a practical base for exploring southeastern Missouri.
The price is $61
$68 total
includes taxes & fees
Jun 1 - Jun 2
Super 8 by Wyndham Charleston/Sikeston East MO
Room, 1 King Bed, Non Smoking | View from room
Eagle Inn Charleston
Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, (106 reviews)
Active travelers will appreciate the health club at this comfortable Charleston motel. Free WiFi keeps you connected, while complimentary parking saves you money. Located within driving distance of Cape Girardeau Municipal Airport for easy regional access.
The price is $69
$77 total
includes taxes & fees
May 12 - May 13
Eagle Inn Charleston
Indoor pool, outdoor pool
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.6 out of 10, Exceptional, (1,014 reviews)
Escape to this serene Sikeston hotel with both indoor and outdoor pools near restaurants and shopping. The fitness center, free breakfast, WiFi and parking enhance your stay, while the helpful staff ensures comfort just minutes from Central Park.
The price is $111
$128 total
includes taxes & fees
May 16 - May 17
Drury Inn & Suites Sikeston, MO
Free daily full breakfast
Best Western Plus Sikeston I-55
Best Western Plus Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very Good, (1,007 reviews)
Experience comfort at this Sikeston hotel, offering free breakfast and parking close to Central Park. The helpful staff welcomes guests to enjoy the indoor pool and fitness center. With easy access to Sikeston Depot Museum, you'll find everything needed for a convenient Missouri stay.
The price is $81
$92 total
includes taxes & fees
May 20 - May 21
Best Western Plus Sikeston I-55
Individually decorated, individually furnished, desk, blackout drapes
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very Good, (774 reviews)
This peaceful hotel offers a complimentary continental breakfast, free WiFi, and convenient parking. Located near I-55 Exit 67, guests consistently praise the helpful staff and clean rooms that provide a quiet retreat after exploring local attractions.
The price is $58
$67 total
includes taxes & fees
May 12 - May 13
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Iron/ironing board, free WiFi, bed sheets
Country Yard Inn and Suite
Country Yard Inn and Suite
2.0 star property
Sikeston
6.8 out of 10, (138 reviews)
This welcoming motel offers convenience with complimentary WiFi and parking, plus round-the-clock front desk assistance. Explore nearby Central Park and Sikeston Depot Museum before returning to your comfortable accommodations.
The price is $63
$75 total
includes taxes & fees
May 12 - May 13
Country Yard Inn and Suite
1 bedroom, desk, laptop workspace, blackout drapes
Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston
2.0 star property
Sikeston
7.4 out of 10, Good, (1,003 reviews)
Travelers rave about this serene retreat with helpful staff and clean rooms. Take advantage of free WiFi, parking, and on-the-go breakfast. Work out in the fitness center before exploring Central Park and Sikeston Depot Museum nearby.
The price is $64
$73 total
includes taxes & fees
May 17 - May 18
Days Inn and Suites by Wyndham Sikeston
Lobby
Quality Inn Cairo I-57
Quality Inn Cairo I-57
2.5 star property
Cairo
6.4 out of 10, (285 reviews)
Set off I-57 in Cairo, this welcoming hotel provides complimentary full breakfast and self parking. Explore nearby Fort Defiance State Park or take a short drive to Ballard Wildlife Management Area while enjoying free WiFi throughout your stay.
The price is $71
$79 total
includes taxes & fees
Jun 6 - Jun 7
Quality Inn Cairo I-57
Exterior
Hampton Inn Sikeston
Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (557 reviews)
Dive into vacation mode at this welcoming hotel with an indoor pool and fitness center near Central Park. After enjoying the complimentary breakfast, explore Sikeston Depot Museum before returning to relax in modern rooms with free WiFi.
The price is $102
$115 total
includes taxes & fees
May 31 - Jun 1
Hampton Inn Sikeston
Exterior
Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (462 reviews)
Experience Sikeston from this hotel with free breakfast, WiFi, and parking. Take a morning dip in the indoor pool or hit the fitness center. Near Central Park and Sikeston Depot Museum, guests love the helpful staff and clean rooms.
The price is $105
$119 total
includes taxes & fees
Jun 7 - Jun 8
Holiday Inn Express & Suites Sikeston Southwest by IHG
Property amenity
Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (75 reviews)
Located in Sikeston, this hotel offers free breakfast, WiFi, and parking. Take a refreshing swim in the indoor pool or grab a bite at the restaurant. Nearby attractions include Central Park and Sikeston Depot Museum for local exploration.
The price is $110
$124 total
includes taxes & fees
May 17 - May 18
Fairfield Inn & Suites by Marriott Sikeston
Property amenity
TownePlace Suites by Marriott Sikeston
TownePlace Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (16 reviews)
The price is $127
$144 total
includes taxes & fees
May 21 - May 22
TownePlace Suites by Marriott Sikeston
Exterior
Comfort Inn & Suites Sikeston I-55
Comfort Inn & Suites Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very Good, (293 reviews)
Warm comfort awaits at this Sikeston hotel where the indoor pool invites morning swims. Just minutes from Central Park and Sikeston Depot Museum, enjoy free WiFi, parking, and a fitness center while helpful staff enhance your stay.
The price is $94
$107 total
includes taxes & fees
Jun 7 - Jun 8
Comfort Inn & Suites Sikeston I-55
Basic Double Room | Living area
La Center Motel
La Center Motel
2.0 star property
La Center
7.6 out of 10, Good, (19 reviews)
Escape to this relaxing La Center hotel with complimentary WiFi and parking. Just a 15-minute drive from Ohio River Valley and 16 minutes from Paducah Regional Airport, the convenient location makes exploring the area effortless.
The price is $60
$70 total
includes taxes & fees
May 12 - May 13
La Center Motel
Exterior
Candlewood Suites Cape Girardeau by IHG
Candlewood Suites Cape Girardeau by IHG
2.5 star property
Cape Girardeau
8.0 out of 10, Very Good, (930 reviews)
The price is $78
$93 total
includes taxes & fees
May 17 - May 18
Candlewood Suites Cape Girardeau by IHG
Lobby
Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (506 reviews)
Experience Mississippi River views and explore Shawnee National Forest from this downtown Marriott. The Bistro serves American cuisine while in-room refrigerators and washers/dryers enhance comfort. Enjoy the 24-hour fitness center after visiting nearby Riverfront Park and Isle Casino.
The price is $125
$142 total
includes taxes & fees
May 29 - May 30
Courtyard by Marriott Cape Girardeau Downtown
Lobby sitting area
The Riverview
The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (566 reviews)
Overlooking the Mississippi River, this hotel puts you near Isle Casino Cape Girardeau and Riverfront Park. Enjoy 2 restaurants including Beacon 53, plus free WiFi and complimentary parking during your business-friendly stay.
The price is $132
$149 total
includes taxes & fees
May 13 - May 14
The Riverview
Lobby
Rockwood Inn
Rockwood Inn
2.0 star property
Cape Girardeau
10.0 out of 10, Exceptional, (20 reviews)
Wake up refreshed at this cozy Cape Girardeau retreat with free WiFi and parking. Explore nearby attractions like Show Me Center and Isle Casino, then unwind in the tranquil garden after your adventures.
The price is $150
$170 total
includes taxes & fees
May 12 - May 13
Rockwood Inn
Lobby
Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (813 reviews)
Wake up to a free breakfast at this Cape Girardeau hotel, just minutes from Shawnee National Forest and the Mississippi River. Swim in the indoor pool, work out in the fitness center, or relax on the terrace after exploring nearby aquatic attractions.
The price is $106
$119 total
includes taxes & fees
May 17 - May 18
Hampton Inn Cape Girardeau I 55 East
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

When is the best time to visit Charleston?

Our prices for hotels in Charleston are cheapest in January
Price trends for hotels in Charleston
Pricing is based on two traveler single night rates
View properties in May
Currently viewing crowd sizes and weather for May.
Typical weather for Charleston
May
High 25°C / low 15°C. Sunny most days.
View properties in May
25°
weather_sun
May, no crowd data, average high temperature 25 degrees Celsius, average low temperature 15 degrees Celsius. Sunny most days.
15°
30°
weather_sun
June, no crowd data, average high temperature 30 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
20°
31°
weather_sun
July, no crowd data, average high temperature 31 degrees Celsius, average low temperature 22 degrees Celsius. Sunny most days.
22°
31°
weather_sun
August, no crowd data, average high temperature 31 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
21°
28°
weather_sun
September, no crowd data, average high temperature 28 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
17°
21°
weather_sun
October, no crowd data, average high temperature 21 degrees Celsius, average low temperature 11 degrees Celsius. Sunny most days.
11°
14°
weather_partly_sunny
November, no crowd data, average high temperature 14 degrees Celsius, average low temperature 5 degrees Celsius. Partly sunny.
5°
9°
weather_partly_sunny
December, no crowd data, average high temperature 9 degrees Celsius, average low temperature 2 degrees Celsius. Partly sunny.
2°
6°
weather_partly_sunny
January, no crowd data, average high temperature 6 degrees Celsius, average low temperature -1 degrees Celsius. Partly sunny.
-1°
8°
weather_partly_sunny
February, no crowd data, average high temperature 8 degrees Celsius, average low temperature 0 degrees Celsius. Partly sunny.
0°
14°
weather_partly_sunny
March, no crowd data, average high temperature 14 degrees Celsius, average low temperature 5 degrees Celsius. Partly sunny.
5°
20°
weather_sun
April, no crowd data, average high temperature 20 degrees Celsius, average low temperature 10 degrees Celsius. Sunny most days.
10°
Monthly weather averages (˚C)

Learn more about Charleston

Charleston is well-known for its attractions such as Mississippi River and Ohio River. Visitors give high marks to the city's restaurants and small-town setting.

See all hotels in Charleston
Cypress Trees on the Horizon. A sting of cypress trees of various sizes extend across the horizon as the sunken sun paints the multicolored sky.

Check out reviews of Charleston hotels guests love

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau

8/10 Good
"The hotel room was very clean and the beds were comfortable, which made for a good night’s sleep. The staff was friendly and the overall stay was pleasant. The only downside was the breakfast. The food selection was limited and the quality was disappointing. Other than breakfast, the hotel experience was good."
Tammy 2-night trip
Posted 7 hours ago
Fairfield Inn & Suites by Marriott Cape Girardeau

Frequently asked questions

What hotels do travelers recommend in Charleston?
Guests like Super 8 by Wyndham Charleston/Sikeston East MO, The Riverstone Hotel Charleston-Sikeston and Eagle Inn Charleston.
Can I book a refundable accommodation in Charleston?
If you're looking for the flexibility to change your plans to Charleston, most accommodations offer refundable* rates you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.
Where should I consider staying in Charleston if I'm looking for a cheap accommodation?
An inexpensive option worth considering is The Riverstone Hotel Charleston-Sikeston.
What will the weather in Charleston be like during my vacation?
July and August are typically the warmest months in Charleston when the average temp is 77°F. January and February are the coldest months when the average temperature is 41°F. April and March are the months with the most rain.
Why should I book my Charleston accommodation with Hotels.com?
There are lots of reasons to book your Charleston trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.