Hotels in Santa Clara

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Where to stay in Santa Clara?

A modern room with a large bathtub, a bed, and a view of lush greenery.

A wooden cabin interior with a large window, a bathtub, and a mirror reflecting the room.

A large bathtub in a room with a view of lush greenery outside.

A bedroom with a large window, a bed with a red blanket, and a hanging light fixture.

Cedro Amazon Lodge

Mera

$145

$145 total

Sep 8 - Sep 9

A wooden deck with a thatched roof structure overlooking a pool, surrounded by dense tropical vegetation.

A modern building with a wooden exterior and a thatched roof entrance.

A wooden cabin interior with a sofa, a dining table, and a chair.

A wooden cabin with a balcony, surrounded by vegetation.

Hamadryade Lodge

Misahualli

$102

$102 total

Oct 1 - Oct 2

A clear pool with reflections of palm trees and a rainbow, surrounded by tropical vegetation and a scenic view.

A wooden structure with a geometric design, surrounded by lush greenery and a small stream.

A wooden structure with a glass enclosure, surrounded by lush greenery.

A circular bed with a canopy in a room with a wooden ceiling and large windows.

Heimatlos Rainforest Lodge

Canelos

$165

$165 total

Sep 5 - Sep 6

A rustic wooden house with a thatched roof, a stone-paved courtyard, and a small pond with floating flowers.

A spacious bedroom with a large bed, wooden headboard, and a wooden floor.

A thatched-roof building surrounded by lush greenery and tropical plants.

A two-story building with a thatched roof, surrounded by lush greenery and a swimming pool with lounge chairs.

Suchipakari Jungle Lodge

Misahualli

$67

$74 total

Sep 11 - Sep 12

A large outdoor swimming pool with a fountain, surrounded by a tiled deck and various seating areas.

A multi-story hotel with a reception area, balconies, and a parking lot.

A hotel room with two beds, a small table, a chair, and a view of the outdoors.

A long, narrow hallway with a tiled floor and walls painted in neutral tones.

Gran Hotel Palmar del Río

Archidona

$36

$36 total

Sep 5 - Sep 6

Cotococha Lodge

Misahualli

A swimming pool surrounded by lush greenery, including palm trees and flowering plants.

A cozy library with bookshelves, a coffee book sign, and comfortable seating.

A building with a sign reading "Hosteria TERRALUNA" and a covered entrance.

Hosteria Terra Luna Lodge

Tena

$138

$138 total

Sep 5 - Sep 6

A covered outdoor area with a wooden deck, two chairs, a table, and a small seating area.

A woman standing by a stream in a forested area.

A serene river surrounded by dense tropical foliage.

A secluded garden with a wooden structure, lush greenery, and a clear view of distant mountains.

Vibra Healing Lodge y Spa

Teniente Hugo Ortiz

$155

$155 total

Sep 6 - Sep 7

A swimming pool with a reflection of surrounding trees and a building with a thatched roof.

A group of people seated at a table, engaged in an activity involving beans.

A rustic building with a thatched roof and a red metal roof, surrounded by lush greenery and a sandy ground.

A spacious lobby with a high ceiling, tiled floor, and a seating area with sofas and armchairs. There is a television on a stand, a fire extinguisher, and a staircase leading to an upper level.

Grand Selva Lodge & Tours

Ahuano

$54

$54 total

Sep 5 - Sep 6

A person sitting on a mat in a thatched-roof structure with potted plants on either side.

A rustic restaurant interior with brick walls, wooden tables, and hanging lights.

A bedroom with a bed, a wooden desk, a mirror, and a hanging light fixture.

Kuyana Amazon Lodge

San Pablo de Ushpayacu

$190

$286 total

Sep 18 - Sep 19

A rustic wooden building with a covered porch, surrounded by lush greenery and a small pond.

A room with a sofa, a hammock, a window with a view of greenery, and a thatched roof.

A room with a television on a wooden stand, a coffee table, and two chairs.

A bedroom with a wooden bed, a window with a view of greenery, a white wall, and a framed picture.

La Penal Amazon Lodge

Cumandá

A bamboo structure with a thatched roof, surrounded by lush greenery and a variety of plants.

A pathway leading to a wooden structure surrounded by lush tropical vegetation.

A room with two beds, a hammock, and a view of greenery.

A wooden hut with a thatched roof surrounded by dense forest.

Huasquila Amazon Lodge

Cotundo

A room with a bed under a white canopy, a window with curtains, and a bed with a headboard.

A stone pathway leading to a wooden structure with a tiled roof, surrounded by lush greenery.

A bathroom with a toilet, a sink, and a mirror above the sink.

A room with a bed, a chair, a table, and a sliding glass door leading to a balcony.

ingaru lodge

Tálag

$48

$445 total

Oct 3 - Oct 4

A wooden deck with a view of a river and dense foliage.

A small, single-story building with a sloped roof, surrounded by lush greenery and a stone pathway leading to the entrance.

A bedroom with a large bed, a wooden headboard, a window with curtains, and a nightstand with a lamp.

A covered outdoor area with a wooden railing, surrounded by lush tropical plants and a stone pathway.

Banana Lodge

Puerto Misahuallí

$59

$59 total

Sep 20 - Sep 21

A venue with a stage, palm trees, and a tropical setting.

A pool hall with multiple pool tables, wooden walls, and a jungle-themed decor.

A bar with a neon sign reading "la Jungle Disco - Billar" and shelves of bottles.

A cozy living room with a brown leather sofa, a wooden coffee table, and a TV mounted on a brick wall. There are two rocking chairs and a small table with a decorative item.

THE JUNGLE Vacation Home

Canelos

$54

$62 total

Sep 5 - Sep 6

A swimming pool with a slide, surrounded by a building with a thatched roof and a balcony.

A two-story building with a red-roofed pavilion in the foreground, surrounded by lush greenery.

A hotel room with three beds, a wooden floor, and a small sitting area.

Hosteria Chuquitos Chalupas

Tena

A wooden bar counter with a glass of iced beverage garnished with a lime slice and a paper towel. A wooden sign with a house illustration and text is visible.

Isla Ecológica Mariana Miller

Misahualli

A wooden structure with a roof, surrounded by lush vegetation and palm trees, at night.

A wooden deck with a view of a river and dense greenery.

A chef in a white uniform and hat preparing food in a kitchen with green walls and a window.

A riverside setting with a sandy beach, rocks, and trees.

Playa Selva Lodge

San Pablo de Ushpayacu

A wooden house with a pool, surrounded by lush greenery and trees.

A wooden bridge leading to a thatched-roof structure surrounded by lush greenery and a small water feature.

A wooden cabin with a thatched roof, a hot tub, and a patio area surrounded by lush tropical plants.

A bedroom with two beds, a wooden ceiling, large windows, and a view of a pool and greenery.

El Jardín Lodge & Spa - Misahualli

Misahualli

A pool with a yellow border, surrounded by green artificial grass and palm trees.

A bedroom with a bed, a sliding glass door leading to an outdoor area with a potted plant, and a window with curtains.

A covered outdoor area with a brick wall and potted plants.

Cabañas Horeb

Puerto Napo

View all properties

Go beyond your typical stay in Santa Clara

Pet friendly

Spa

Pool

Check out reviews of Santa Clara hotels guests love

Cedro Amazon Lodge

10/10 Excellent

"Staying in a luxurious home while being completely immersed in the Amazon rainforest, surrounded by the sounds and lush vegetation, was such a unique experience. The energy of this place is incredibly peaceful and rejuvenating. The host was exceptionally kind, thoughtful, attentive to our needs, and always quick to respond. I highly recommend this place — truly magical! 🌿✨"

Hostal Posada Real

10/10 Excellent

"We were able to go in late easily and it was very centrral to our event. They also served us a nice breakfast and the room was laid out nice with super comfy pillows and mattress. A bit pricey though."

Gran Hotel Palmar del Río

10/10 Excellent

"Pool and jacuzzi were maintained daily and it was the perfect way to finish off the day with a couple of beers. Alcohol and snacks are sold half a block away. Breakfast was decent, staff friendly and there is enough parking. Make sure to close the windows at night unless you want to be awaken by roosters at 5am."

Suchipakari Jungle Lodge

10/10 Excellent

"Muy buen alojamiento"

Hamadryade Lodge

10/10 Excellent

"La habitación estaba impecable y tenía buenos servicios"

Hostal Tena Ñaui

8/10 Good

"Nice big rooms , clean crisp sheets and comfy bed. Efficient airconditioning and close to everything "

Frequently asked questions

What hotels do travelers recommend in Santa Clara?

Guests like Vibra Healing Lodge y Spa.

Can I book a refundable hotel in Santa Clara?

If you need the flexibility to change your plans to Santa Clara, most hotels offer refundable* rates you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.

What will the weather in Santa Clara be like during my vacation?

The warmest months in Santa Clara are usually September and October with an average temp of 66°F. July and August are the chilliest months when the average temp is 64°F. The rainiest months are April and May.

Why should I book my Santa Clara hotel through Hotels.com?

There are plenty of reasons to book your Santa Clara travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.