Hotels in Florence

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Check prices for these dates

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Where to stay in Florence?

Interior entrance
Hotel Bothwell Sedalia Central District, an Ascend Collection Hotel
Hotel Bothwell Sedalia Central District, an Ascend Collection Hotel
3.0 star property
9.2 out of 10, Wonderful, (582)
  • cleanliness
    Historic charm meets modern comfort in this Central District boutique hotel.
The price is $110
$125 total
includes taxes & fees
Jan 28 - Jan 29, 2026
Hotel Bothwell Sedalia Central District, an Ascend Collection Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Check out reviews of Florence hotels guests love

Comfort Inn Sedalia Station

Comfort Inn Sedalia Station

10/10 Excellent
"Staff was super welcoming and room was clean and neat."
Reed 1-night trip
Posted 3 days ago
Comfort Inn Sedalia Station

Frequently asked questions

What hotels do travelers like in Florence?
Guests like Florence Cabin w/ On-site Creek!, Creek Views & Grill: Idyllic Florence Cabin and Unique Creekside Escape - Enjoy On-site Goats!.
Can I book refundable accommodations in Florence?
If you're looking for the flexibility to change your plans to Florence, most hotels offer refundable* rates you can book. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.
What will the weather in Florence be like during my trip?
The warmest months in Florence are usually July and August with an average temp of 75°F. January and February are the chilliest months when the average temp is 37°F. The rainiest months are May and April.
Why should I book my Florence hotel with Hotels.com?
There are plenty of reasons to book your Florence travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.