Hotels in Santa Clara
Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices
Check prices for these dates
Top 5 hotels in Santa Clara at a glance
- Hotel Riu Plaza Panama — 5-star hotel in Campo Alegre, 8 km from Santa Clara. Guest rating: 9.0/10 — Wonderful.
- Corporate Stays Arcadia | Executive Furnished Apartments — 4-star hotel in Costa del Este, 2.8 km from Santa Clara. Guest rating: 9.2/10 — Wonderful.
- Principe Hotel and Suites — 3-star hotel in El Cangrejo, 7.8 km from Santa Clara. Guest rating: 9.0/10 — Wonderful.
- JW Marriott Panama — 5-star hotel in Punta Pacifica, 7.8 km from Santa Clara. Guest rating: 9.0/10 — Wonderful.
- Riande Urban Hotel — 3.5-star hotel in El Cangrejo, 7.9 km from Santa Clara. Guest rating: 8.8/10 — Excellent.
Where to stay in Santa Clara?
Hotel Riu Plaza Panama
Hotel Riu Plaza PanamaCampo Alegre, 8 km from Santa Clara
9.0 out of 10, Wonderful, (5,771 reviews)
"Very nice clean spacious rooms with great breakfast!"
Petronella
The price is $132
$145 total
includes taxes & fees
Sep 1 - Sep 2
Corporate Stays Arcadia | Executive Furnished Apartments
Corporate Stays Arcadia | Executive Furnished ApartmentsCosta del Este, 2.8 km from Santa Clara
9.2 out of 10, Wonderful, (337 reviews)
"Good location in a nice building w facilities"
anders
The price is $100
$163 total
includes taxes & fees
Aug 5 - Aug 6
Principe Hotel and Suites
Principe Hotel and SuitesEl Cangrejo, 7.8 km from Santa Clara
9.0 out of 10, Wonderful, (1,998 reviews)
"Cesar is wonderfully helpful and professional. Thanks for another comfortable stay."
Emily
The price is $57
$62 total
includes taxes & fees
Aug 6 - Aug 7
JW Marriott Panama
JW Marriott PanamaPunta Pacifica, 7.8 km from Santa Clara
9.0 out of 10, Wonderful, (1,002 reviews)
"Very nice and safe place to stay"
Nilesh
The price is $263
$290 total
includes taxes & fees
Aug 29 - Aug 30
Riande Urban Hotel
Riande Urban HotelEl Cangrejo, 7.9 km from Santa Clara
8.8 out of 10, Excellent, (1,028 reviews)
"Everything was excellent and great location. "
Victor
The price is $107
$118 total
includes taxes & fees
Aug 31 - Sep 1
Ramada Plaza by Wyndham Panama Punta Pacifica
Ramada Plaza by Wyndham Panama Punta PacificaSan Francisco, 6.6 km from Santa Clara
9.6 out of 10, Exceptional, (1,286 reviews)
"Hotel was amazing! The room was spacious, the breakfast was amazing and the location was great! Would stay here again for sure!"
Kristen
The price is $118
$130 total
includes taxes & fees
Aug 8 - Aug 9
Aloft by Marriott Panama
Aloft by Marriott PanamaSan Francisco, 6.1 km from Santa Clara
8.8 out of 10, Excellent, (1,003 reviews)
"Convenient location, great bakery inside, offers adjoining room for family"
Matthew
The price is $119
$131 total
includes taxes & fees
Aug 14 - Aug 15
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama CityJuan Diaz, 2.8 km from Santa Clara
9.6 out of 10, Exceptional, (724 reviews)
"Nice location good food "
Ramon
The price is $239
$263 total
includes taxes & fees
Aug 7 - Aug 8
Novotel Panama City
Novotel Panama CityEl Cangrejo, 7.5 km from Santa Clara
9.2 out of 10, Wonderful, (1,260 reviews)
"Large rooms, large beds, quiet AC, decent breakfast, great location"
Lancelot
The price is $114
$126 total
includes taxes & fees
Sep 3 - Sep 4
Courtyard by Marriott Panama Multiplaza Mall
Courtyard by Marriott Panama Multiplaza MallSan Francisco, 7.2 km from Santa Clara
9.0 out of 10, Wonderful, (1,002 reviews)
"Breakfast was great and Shops being nearby was fantastic, especially for my daughter"
Christopher
The price is $118
$130 total
includes taxes & fees
Aug 8 - Aug 9
Megapolis Hotel Panamá
Megapolis Hotel PanamáPunta Paitilla, 8.2 km from Santa Clara
8.4 out of 10, Very Good, (1,633 reviews)
"I had a wonderful stay. Room was spacious and very comfy"
Richard
The price is $209
$230 total
includes taxes & fees
Aug 28 - Aug 29
Courtyard by Marriott Panama Metromall
Courtyard by Marriott Panama Metromall3.2 km from Santa Clara
9.0 out of 10, Wonderful, (1,012 reviews)
"Great service, very comfortable beds, truly excellent breakfast manager and staff. "
Elizabeth
The price is $98
$108 total
includes taxes & fees
Aug 14 - Aug 15
Sheraton Grand Panama
Sheraton Grand PanamaSan Francisco, 6.1 km from Santa Clara
8.6 out of 10, Excellent, (1,000 reviews)
"The staff greeted us with a warm smile every day. The breakfast was delicious. We would definitely stay here again. "
James
The price is $171
$188 total
includes taxes & fees
Aug 21 - Aug 22
The Westin Panama
The Westin PanamaCosta del Este, 3 km from Santa Clara
9.0 out of 10, Wonderful, (339 reviews)
"Clean room, helpful staff, good breakfast."
Stephanie
The price is $214
$236 total
includes taxes & fees
Aug 22 - Aug 23
The District Hotel Panama
The District Hotel PanamaEl Cangrejo, 7.9 km from Santa Clara
7.4 out of 10, Good, (20 reviews)
"Pretty much what one would expect to get for $69 per night...Friendly, helpful staff..."
charla
The price is $76
$84 total
includes taxes & fees
Aug 9 - Aug 10
Crowne Plaza Panama Airport by IHG
Crowne Plaza Panama Airport by IHG10.2 km from Santa Clara
8.6 out of 10, Excellent, (2,633 reviews)
"Nice hotel close to the airport"
Ernest
The price is $144
$165 total
includes taxes & fees
Aug 9 - Aug 10
The Executive Hotel
The Executive HotelCampo Alegre, 8.4 km from Santa Clara
9.2 out of 10, Wonderful, (1,213 reviews)
"Excellent cleaness, good breakfast and very helpfull staff"
MARISELA
The price is $89
$98 total
includes taxes & fees
Aug 17 - Aug 18
Residence Inn by Marriott Panama City
Residence Inn by Marriott Panama CityPunta Paitilla, 7.8 km from Santa Clara
9.2 out of 10, Wonderful, (660 reviews)
"Great place to stay in Panama City! Gorgeous views from the ocean side of the hotel, nice rooftop pool and gym. The breakfast was also great. We loved that it was attached to the Pacific Center (arcade, bowling alley, restaurant and more). Overall I would stay there again!!"
Kimberly
The price is $206
$227 total
includes taxes & fees
Aug 31 - Sep 1
Waymore Hotel Spa & Casino
Waymore Hotel Spa & CasinoEl Cangrejo, 8.3 km from Santa Clara
9.0 out of 10, Wonderful, (1,051 reviews)
"Hotel Waymore is a great place to stay. It is footsteps away from restaurants and shops."
Gregory
The price is $105
$116 total
includes taxes & fees
Sep 1 - Sep 2
Hyatt Regency Panama City
Hyatt Regency Panama CityCampo Alegre, 8.2 km from Santa Clara
9.6 out of 10, Exceptional, (399 reviews)
"Lovely room - Big and very clean. Loved it after a night on the San Blas Island."
Helle
The price is $224
$246 total
includes taxes & fees
Aug 22 - Aug 23
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Check out reviews of Santa Clara hotels guests love
Hotel Riu Plaza Panama
10/10 Excellent
Find out more about Santa Clara