Hotels in Santee

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Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (843 reviews)
Bright, modern hotel near Santee National Golf Club with a refreshing indoor pool for year-round swimming. Guests love the complimentary breakfast, 24-hour fitness center, and helpful staff. Free WiFi and parking add convenience to your Santee visit.
The price is $106
$118 total
includes taxes & fees
Jun 14 - Jun 15
Tru By Hilton Santee

Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1,470 reviews)
Escape to this quiet Santee hotel where comfortable beds await after exploring local golf clubs. Free perks include daily continental breakfast, WiFi, and parking. Guests praise the convenient location close to everything they need.
The price is $80
$89 total
includes taxes & fees
Jun 7 - Jun 8
Baymont by Wyndham Santee

Best Western Plus Santee Inn

Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1,003 reviews)
The price is $110
$122 total
includes taxes & fees
Jun 21 - Jun 22
Best Western Plus Santee Inn

Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
2.0 star property
Santee
7.2 out of 10, Good, (737 reviews)
The price is $63
$70 total
includes taxes & fees
Jun 11 - Jun 12
Travelodge by Wyndham Santee

Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
3.0 star property
Santee
9.8 out of 10, Exceptional, (1,006 reviews)
Guests love this quiet Santee hotel for its helpful staff and complimentary breakfast. The outdoor pool and health club offer refreshing workout options, while free parking and WiFi add convenience. Golf enthusiasts will appreciate the nearby Santee Cooper Country Club.
The price is $134
$149 total
includes taxes & fees
Jun 14 - Jun 15
Fairfield Inn & Suites by Marriott Santee

Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1,009 reviews)
This peaceful hotel in Santee's entertainment district offers a quiet retreat with free breakfast and parking. Located near Santee Cooper Country Club, guests can enjoy the fitness center or take a refreshing dip in the seasonal pool. The staff earns consistent praise for their helpfulness.
The price is $97
$108 total
includes taxes & fees
Jun 28 - Jun 29
Comfort Inn & Suites Santee

Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
2.5 star property
Santee
9.6 out of 10, Exceptional, (1,003 reviews)
The price is $119
$132 total
includes taxes & fees
Jun 21 - Jun 22
Hampton Inn Santee-I-95

Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
2.5 star property
Santee
6.0 out of 10, (538 reviews)
Wake up to free breakfast at this convenient Santee hotel with 7 dining options and a seasonal outdoor pool. After exploring nearby Santee Cooper Country Club, unwind at the bar. Clean rooms, helpful staff, and free WiFi and parking enhance your stay.
The price is $55
$67 total
includes taxes & fees
Jun 28 - Jun 29
Quality Inn & Suites Santee I-95

Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
3.0 star property
Santee
8.2 out of 10, Very Good, (1,002 reviews)
Swing into action at this golf-adjacent hotel featuring an indoor pool and 24-hour fitness center. Relax on the terrace or enjoy a drink at the bar after playing nearby Santee Cooper Country Club. Clean rooms with refrigerators and microwaves create a comfortable home base.
The price is $99
$110 total
includes taxes & fees
Jun 14 - Jun 15
Holiday Inn Santee by IHG

Super 8 by Wyndham Santee/I-95

Super 8 by Wyndham Santee/I-95
2.0 star property
Santee
6.8 out of 10, (465 reviews)
Overlooking a golf course, this tranquil motel offers a refreshing seasonal outdoor pool and complimentary breakfast served daily. Located near Santee Cooper Country Club, guests enjoy free WiFi and parking during their stay.
The price is $64
$71 total
includes taxes & fees
Jun 14 - Jun 15
Super 8 by Wyndham Santee/I-95

Red Roof Inn Santee

Red Roof Inn Santee
2.0 star property
Santee
6.6 out of 10, (655 reviews)
Minutes from Santee Cooper Country Club, this welcoming hotel offers free WiFi, parking, and daily continental breakfast. Adventure seekers will appreciate the nearby water skiing opportunities, while golf enthusiasts can enjoy Santee National Golf Club just a short drive away.
The price is $63
$70 total
includes taxes & fees
Jun 9 - Jun 10
Red Roof Inn Santee

Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95
2.0 star property
Santee
6.4 out of 10, (563 reviews)
Steps from Santee Cooper Country Club, this hotel offers rooms with refrigerators and microwaves. After a round of golf, enjoy the poolside bar and on-site restaurant. Free WiFi and parking make exploring nearby attractions easy.
The price is $71
$79 total
includes taxes & fees
Jul 5 - Jul 6
Ramada by Wyndham Santee I-95

Econo Lodge Santee

Econo Lodge Santee
2.0 star property
Santee
6.4 out of 10, (314 reviews)
Located near Santee Cooper Country Club, this hotel offers free WiFi and parking. You'll appreciate the 24-hour front desk service while exploring nearby attractions including Santee National Golf Club.
The price is $64
$71 total
includes taxes & fees
Jul 5 - Jul 6
Econo Lodge Santee

Doyles B and B at Players course LLC

Doyles B and B at Players course LLC
3.5 star property
Manning
The price is $181
$201 total
includes taxes & fees
Jun 7 - Jun 8
Doyles B and B at Players course LLC

Peach Tree Inn

Peach Tree Inn
2.5 star property
St. George
7.2 out of 10, Good, (219 reviews)
The price is $65
$70 total
includes taxes & fees
Jul 5 - Jul 6
Peach Tree Inn

Crown Inn By Oyo Orangeburg Hwy 301

Crown Inn By Oyo Orangeburg Hwy 301
2.5 star property
Orangeburg
2.8 out of 10, (9 reviews)
Tucked away on Highway 301, this convenient Orangeburg hotel offers cozy accommodations with complimentary WiFi and parking. Nearby attractions include Edisto Memorial Gardens and South Carolina State College Historic District. Enjoy room service during your stay.
The price is $50
$61 total
includes taxes & fees
Jun 7 - Jun 8
Crown Inn By Oyo Orangeburg Hwy 301

Best Inn of Manning

Best Inn of Manning
2.5 star property
Manning
6.8 out of 10, (32 reviews)
The price is $68
$76 total
includes taxes & fees
Jun 9 - Jun 10
Best Inn of Manning

Orangeburg Inn & Suites

Orangeburg Inn & Suites
2.0 star property
Orangeburg
6.2 out of 10, (74 reviews)
This Orangeburg hotel offers free WiFi and parking with 24-hour front desk service. Visit nearby Edisto Memorial Gardens or South Carolina State College Historic District for local exploration during your stay.
The price is $54
$61 total
includes taxes & fees
Jun 7 - Jun 8
Orangeburg Inn & Suites

SureStay Hotel by Best Western Manning

SureStay Hotel by Best Western Manning
2.5 star property
Manning
8.6 out of 10, Excellent, (1,004 reviews)
Travelers appreciate the helpful staff at this hotel in Manning. Start your day with complimentary full breakfast before exploring. Enjoy conveniences like free WiFi and parking, plus business-friendly amenities for a relaxing stay.
The price is $85
$94 total
includes taxes & fees
Jun 21 - Jun 22
SureStay Hotel by Best Western Manning

Southern Lodge 601

Southern Lodge 601
Orangeburg
7.6 out of 10, Good, (10 reviews)
The price is $76
$84 total
includes taxes & fees
Jun 7 - Jun 8
Southern Lodge 601
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Check out pet-friendly hotels in Santee

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

When is the best time to visit Santee?

Our prices for hotels in Santee are cheapest in November
Price trends for hotels in Santee
Pricing is based on two traveler single night rates
View properties in June
Currently viewing crowd sizes and weather for June.
Typical weather for Santee
June
High 31°C / low 21°C. Sunny most days.
View properties in June
31°
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June, no crowd data, average high temperature 31 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
21°
33°
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July, no crowd data, average high temperature 33 degrees Celsius, average low temperature 23 degrees Celsius. Sunny most days.
23°
32°
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August, no crowd data, average high temperature 32 degrees Celsius, average low temperature 23 degrees Celsius. Sunny most days.
23°
29°
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September, no crowd data, average high temperature 29 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
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24°
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October, no crowd data, average high temperature 24 degrees Celsius, average low temperature 15 degrees Celsius. Sunny most days.
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19°
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November, no crowd data, average high temperature 19 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
15°
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December, no crowd data, average high temperature 15 degrees Celsius, average low temperature 7 degrees Celsius. Sunny most days.
13°
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January, no crowd data, average high temperature 13 degrees Celsius, average low temperature 4 degrees Celsius. Sunny most days.
16°
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February, no crowd data, average high temperature 16 degrees Celsius, average low temperature 6 degrees Celsius. Sunny most days.
19°
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March, no crowd data, average high temperature 19 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
24°
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April, no crowd data, average high temperature 24 degrees Celsius, average low temperature 13 degrees Celsius. Sunny most days.
13°
28°
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May, no crowd data, average high temperature 28 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
17°
Monthly weather averages (˚C)

Top landmarks in Santee

Learn more about Santee

Tee off at championship golf courses or cast a line in Lake Marion's fish-rich waters where locals claim the bass practically jump into your boat. The Santee National Wildlife Refuge offers hiking trails where alligators sun themselves with reptilian nonchalance. Interstate 95 crosses the lake on a causeway that provides views worth pulling over for (safely, of course). Santee State Park delivers lakeside tranquility that makes visitors forget their phones exist. This resort town punches well above its weight with dining options that range from fresh-caught catfish to surprisingly sophisticated fare. The recent addition of the Santee Cooper Regional Water System has locals buzzing about growth while still cherishing their small-town atmosphere.

Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina

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Frequently asked questions

What accommodations do travelers like in Santee?
Can I book refundable accommodations in Santee?
If you want the flexibility to change your plans to Santee, most accommodations provide refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.
Where should I stay in Santee if I'm looking for a reasonably priced accommodation?
A few inexpensive options worth considering are Baymont by Wyndham Santee, Tru By Hilton Santee and Comfort Inn & Suites Santee.
Where can I stay in Santee if I want a vacation rental instead of a hotel?
Browse 8 vacation homes on our site. You also might want to book one of 101 condos for your trip.
What will the weather in Santee be like during my vacation?
July and August are typically the warmest months in Santee when the average temp is 79°F. January and February are the coldest months when the average temperature is 52°F. August and July are the months with the most rain.
Why should I book my Santee hotel with Hotels.com?
There are lots of reasons to book your Santee trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.