Hotels in Seneca

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Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123
2.5 star property
Downtown
8.0 out of 10, Very Good, (739 reviews)
Serene hotel within a 15-minute drive of Clemson University offers a seasonal outdoor pool, complimentary WiFi, parking, and breakfast. Toy Train Park and The Gauntlet attractions are nearby, with guests consistently praising the quiet atmosphere and attentive service.
The price is $76
$93 total
includes taxes & fees
Jul 30 - Jul 31
Quality Inn Seneca Clemson Area US-123

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
Seneca
6.8 out of 10, (767 reviews)
This Seneca motel offers easy access to Clemson University and Lake Keowee. Take a refreshing dip in the seasonal outdoor pool after exploring nearby Lake Hartwell. Free WiFi, parking, and daily on-the-go breakfast add exceptional value.
The price is $71
$78 total
includes taxes & fees
Jul 31 - Aug 1
Days Inn by Wyndham Seneca / Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
2.5 star property
Seneca
9.2 out of 10, Wonderful, (728 reviews)
Just 5 minutes from Lake Keowee, this hotel offers a 24-hour fitness center and seasonal outdoor swimming. Enjoy complimentary breakfast, WiFi, and parking while staying close to Clemson University. Guests consistently praise the helpful staff and clean accommodations.
The price is $119
$131 total
includes taxes & fees
Jul 23 - Jul 24
Hampton Inn & Suites Seneca-Clemson Area

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
2.5 star property
Seneca
9.2 out of 10, Wonderful, (865 reviews)
This convenient Seneca hotel offers a complimentary morning meal, fitness center, and free parking just 5 minutes from campus. Guests praise the attentive staff, while Littlejohn Coliseum and Sloan Tennis Center are located nearby.
The price is $106
$116 total
includes taxes & fees
Jul 27 - Jul 28
Tru by Hilton Seneca Clemson

Best Western Seneca-Clemson

Best Western Seneca-Clemson
2.5 star property
Seneca
8.4 out of 10, Very Good, (678 reviews)
Located within a 10-minute drive of Clemson University, this Seneca hotel offers a seasonal outdoor pool and free daily breakfast. Guests appreciate the helpful staff and clean rooms, while enjoying convenient access to local attractions.
The price is $94
$103 total
includes taxes & fees
Aug 2 - Aug 3
Best Western Seneca-Clemson

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
3.0 star property
Seneca
9.4 out of 10, Exceptional, (249 reviews)
Minutes from Clemson University and Lakes Keowee and Hartwell, this Seneca hotel offers free breakfast and parking. Refresh at the outdoor pool or fitness center after exploring nearby Golden Corner Plaza and Gignilliat Community Center.
The price is $129
$142 total
includes taxes & fees
Jul 27 - Jul 28
Fairfield Inn & Suites Seneca Clemson Univ Area

Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
Seneca
9.0 out of 10, Wonderful, (1,003 reviews)
Unwind at this lakeside retreat with a poolside bar and seasonal outdoor pool just minutes from Clemson University. The 24-hour fitness center and hot tub provide recreation options while the restaurant and lounge offer on-site dining convenience.
The price is $109
$135 total
includes taxes & fees
Jul 21 - Jul 22
Lakeside Lodge Clemson

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (90 reviews)
Tucked between Lake Hartwell and Lake Keowee, these charming cabins offer serene patios and well-equipped kitchenettes. Just minutes from outdoor recreation areas and Cross Creek Plantation Golf, with free parking and cozy climate control for year-round comfort.
The price is $93
$146 total
includes taxes & fees
Jul 27 - Jul 28
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Beautiful Lake Keowee Home w/ Boat Dock & Fire Pit

Beautiful Lake Keowee Home w/ Boat Dock & Fire Pit
3.0 star property
Seneca
The price is $634
$1,054 total
includes taxes & fees
Aug 9 - Aug 10
Beautiful Lake Keowee Home w/ Boat Dock & Fire Pit

Hampton Inn Clemson-University Area

Hampton Inn Clemson-University Area
2.5 star property
Clemson
8.8 out of 10, Excellent, (645 reviews)
Unwind at this well-positioned hotel near Larry W. Abernathy Waterfront Park, offering a seasonal outdoor pool for morning swims. Free breakfast, WiFi, and parking await, with Clemson Station just a 19-minute walk away.
The price is $102
$114 total
includes taxes & fees
Aug 2 - Aug 3
Hampton Inn Clemson-University Area

Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
3.0 star property
Clemson
9.4 out of 10, Exceptional, (1,004 reviews)
Set on the grounds of Clemson University, this welcoming hotel offers direct access to Walker Golf Course, a seasonal outdoor pool, and poolside bar. Enjoy American cuisine at Sole on the Green or squeeze in a workout at the 24-hour fitness center while exploring campus.
The price is $144
$160 total
includes taxes & fees
Jul 21 - Jul 22
Clemson University's James F. Martin Inn

Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
2.5 star property
Clemson
8.4 out of 10, Very Good, (1,005 reviews)
Take a dip in the seasonal outdoor pool at this Clemson hotel, just a 15-minute drive from Clemson University. Enjoy free breakfast, parking, and fitness center access, with African American Museum and Waterfront Park nearby.
The price is $104
$115 total
includes taxes & fees
Jul 27 - Jul 28
Comfort Inn & Suites Clemson - University Area

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
Clemson
8.2 out of 10, Very Good, (1,006 reviews)
Walking distance from Clemson Station, this welcoming hotel sits just 5 minutes from the university campus. After a free breakfast, cool off in the seasonal outdoor pool or hit the 24-hour fitness center. Nearby attractions and quiet, comfortable rooms await.
The price is $101
$112 total
includes taxes & fees
Jul 22 - Jul 23
Best Western Plus Clemson Hotel & Conference Center

Inn @ Clemson

Inn @ Clemson
2.5 star property
Clemson
8.0 out of 10, Very Good, (1,002 reviews)
Take advantage of the complimentary breakfast, WiFi and parking at this hotel near Lake Hartwell and Clemson University. Guests praise the helpful staff, clean rooms and quiet environment. The fitness center adds value for active travelers.
The price is $89
$99 total
includes taxes & fees
Jul 21 - Jul 22
Inn @ Clemson

Rodeway Inn & Suites Walhalla

Rodeway Inn & Suites Walhalla
2.0 star property
Walhalla
7.6 out of 10, Good, (191 reviews)
Wake up to complimentary continental breakfast at this welcoming Walhalla motel. Located near Art Circle Gallery and Goldfish Pond, the property offers free WiFi and parking. Just a 22-minute drive from Clemson Station for easy regional exploration.
The price is $67
$74 total
includes taxes & fees
Jul 26 - Jul 27
Rodeway Inn & Suites Walhalla

The Point At Lake Hartwell

The Point At Lake Hartwell
3.0 star property
Townville
The price is $125
$139 total
includes taxes & fees
Jul 21 - Jul 22
The Point At Lake Hartwell

The Abernathy of Clemson

The Abernathy of Clemson
4.0 star property
Clemson
9.6 out of 10, Exceptional, (625 reviews)
Experience Southern hospitality at this refined Clemson hotel just minutes from campus attractions. Unwind with a cocktail at the stylish bar after exploring nearby Sloan Tennis Center and Littlejohn Coliseum. Free parking and convenient location make this an ideal collegiate getaway.
The price is $152
$169 total
includes taxes & fees
Aug 5 - Aug 6
The Abernathy of Clemson

Days Inn by Wyndham Clemson

Days Inn by Wyndham Clemson
3.5 star property
Clemson
6.8 out of 10, (223 reviews)
Just a 5-minute drive from Clemson University, this hotel offers convenient perks including free WiFi, parking, and daily continental breakfast. Nearby attractions include the African American Museum and Larry W. Abernathy Waterfront Park.
The price is $76
$84 total
includes taxes & fees
Jul 21 - Jul 22
Days Inn by Wyndham Clemson

The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
4.0 star property
Clemson
9.8 out of 10, Exceptional, (847 reviews)
Moments from Lake Hartwell, this hotel blends walkable access to campus with comfort. Enjoy attentive service, a welcoming restaurant, and stylish bar where you can unwind. Just a 13-minute walk from Clemson Station connects you to broader adventures.
The price is $169
$188 total
includes taxes & fees
Jul 27 - Jul 28
The Shepherd Hotel Downtown Clemson

The Inn at Patrick Square

The Inn at Patrick Square
3.5 star property
Clemson
9.8 out of 10, Exceptional, (878 reviews)
Enjoy free WiFi and parking at this hotel just 5 minutes from Clemson University. Clean rooms provide a comfortable base while exploring nearby Botanical Gardens and African American Museum. The friendly staff ensures a pleasant stay in Clemson.
The price is $149
$165 total
includes taxes & fees
Jul 21 - Jul 22
The Inn at Patrick Square
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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When is the best time to visit Seneca?

Our prices for hotels in Seneca are cheapest in December
Price trends for hotels in Seneca
Pricing is based on two traveler single night rates
View properties in July
Currently viewing crowd sizes and weather for July.
Typical weather for Seneca
July
High 32°C / low 21°C. Sunny most days.
View properties in July
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July, no crowd data, average high temperature 32 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
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August, no crowd data, average high temperature 31 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
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September, no crowd data, average high temperature 28 degrees Celsius, average low temperature 18 degrees Celsius. Sunny most days.
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October, no crowd data, average high temperature 23 degrees Celsius, average low temperature 12 degrees Celsius. Sunny most days.
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November, no crowd data, average high temperature 17 degrees Celsius, average low temperature 6 degrees Celsius. Sunny most days.
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December, no crowd data, average high temperature 12 degrees Celsius, average low temperature 4 degrees Celsius. Sunny most days.
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January, no crowd data, average high temperature 10 degrees Celsius, average low temperature 1 degrees Celsius. Partly sunny.
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March, no crowd data, average high temperature 17 degrees Celsius, average low temperature 6 degrees Celsius. Sunny most days.
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April, no crowd data, average high temperature 22 degrees Celsius, average low temperature 10 degrees Celsius. Sunny most days.
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May, no crowd data, average high temperature 26 degrees Celsius, average low temperature 15 degrees Celsius. Sunny most days.
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June, no crowd data, average high temperature 31 degrees Celsius, average low temperature 19 degrees Celsius. Sunny most days.
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Monthly weather averages (ËšC)

Top neighborhoods in Seneca

Downtown

Downtown Seneca charms visitors with well-preserved historical buildings that tell the story of its railroad heritage. The tree-lined Ram Cat Alley showcases local history through colorful murals, while the old courthouse square hosts seasonal farmers markets and community events. You can explore the Bertha Lee Strickland Cultural Museum or browse antique shops filled with Southern treasures. Family-owned cafes serve up delicious Southern comfort food like fried green tomatoes and barbecue. Accommodations range from historic bed & breakfasts in Victorian homes to budget-friendly motels. The entire downtown is walkable with wide sidewalks, making it easy to discover this authentic slice of small-town America at your own pace.

Serenity Bay

Lake Keowee beckons from this peaceful coastal retreat nestled in Saxony Forest. Serenity Bay lives up to its name with tree-lined streets perfect for contemplative walks. Nearby Keowee Key Golf Course offers tee times for enthusiasts, while South Beach provides sandy relaxation without the crowds. The natural setting creates an ideal escape for bird watchers and nature photographers. Vacation rentals with weathered wood siding and muted earth tones blend seamlessly into the forest canopy. Getting around requires your own wheels since public transit is limited. The neighborhood trades bustling nightlife for cricket choruses and ocean breezes filtering through pine trees—exactly what makes this hidden gem worth finding.

Pine Ridge Point

Lake Keowee sparkles as the crown jewel of Pine Ridge Point, a peaceful residential haven in Seneca. Waterfront vacation homes nestle among tall pines, offering private docks and stunning views. Visitors spend days swimming in crystal-clear waters, boating across the lake, or simply unwinding on expansive decks beneath Carolina blue skies. This neighborhood is all about authentic lakeside living without commercial distractions. Most travelers cook in well-equipped rental kitchens or drive 15 minutes to Seneca for restaurants. Personal vehicles are essential for getting around, though scenic paths along the shoreline make for perfect evening strolls.

Indian Oaks

Indian Oaks gives you all the peaceful vibes of suburban life with none of the tourist chaos. This leafy neighborhood in Seneca lets you live like a local under a canopy of mature oak trees. The curved streets and manicured lawns create a park-like setting that's perfect for morning walks. Lake Keowee is just a short drive away when you need a water fix. You'll need wheels to get around since public transit is limited and restaurants aren't within walking distance. Most visitors stay in vacation rental homes with private yards and driveways. The neighborhood gets incredibly quiet after dark—ideal for travelers who want to experience authentic suburban living while having Seneca's attractions nearby.

Top landmarks in Seneca

Learn more about Seneca

Between the crystal waters of Lake Keowee and the misty cascade of Isaqueena Falls lies a playground for outdoor enthusiasts. Kayak across the lake while keeping an eye out for bald eagles soaring overhead and blue herons stalking the shallows. The lush forests of Oconee State Park offer hiking trails for every skill level, with shade-dappled paths winding through ancient trees. Twin Lakes Recreation Area provides family-friendly spots to picnic after a morning on the water. Dog owners shouldn't miss The Pier Dog Park, where four-legged friends can splash along the shoreline. After a day of adventure, the coffeehouses in the historic downtown offer the perfect place to recharge while planning tomorrow's excursion to Keowee Key Golf Course or Lake Hartwell.

A calm lake with mountains in the background.

Check out reviews of Seneca hotels guests love

Frequently asked questions

What accommodations do travelers like in Seneca?
Can I book refundable accommodations in Seneca?
If you want the flexibility to change your travel plans to Seneca, most accommodations offer refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in Seneca if I want a budget-friendly accommodation?
Lakeside Lodge Clemson, Quality Inn Seneca Clemson Area US-123 and Tru by Hilton Seneca Clemson are a few accommodations you might want to consider that'll save you money.
Where can I stay in Seneca if I want a vacation rental instead of a hotel?
If you want to find a good alternative to a hotel, review our selection of 206 vacation homes. In addition, there are 21 apartments and 12 condos.
What will the weather in Seneca be like during my visit?
The warmest months in Seneca are usually July and August with an average temp of 76°F. January and February are the chilliest months when the average temp is 46°F. The rainiest months are December and January.
Why should I book my Seneca hotel with Hotels.com?
There are plenty of reasons to book your Seneca travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Keyâ„¢, our rewards program, you will be able to earn and use OneKeyCashâ„¢* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.