Hotels in La Mesa

City, hotel name, or address

Dates

Travelers

I'm traveling for business

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Where to stay in La Mesa?

A room with a bed, a desk with a chair, a television, and a door.

A small kitchenette with a microwave, coffee maker, and a toaster. There are two black bar stools and a TV mounted on the wall displaying movie recommendations.

A bathroom with a bathtub, a sink, a window, and towels.

A hotel room with a bed, a desk, a TV, and a kitchenette.

1. Tocumen Comfort Stay

24 de Diciembre

$45

$50 total

includes taxes & fees

Oct 21 - Oct 22

A room with two beds, a desk with chairs, a television, and a window with blinds.

A kitchen with a wooden cabinet, a TV mounted on the wall, and three bar stools.

A small kitchenette with a microwave, a coffee maker, and a refrigerator. There are two chairs and a sofa.

A compact kitchen with a microwave, two stools, a small refrigerator, and a flat-screen TV mounted on the wall.

2. B&B Lodgings

24 de Diciembre

$49

$54 total

includes taxes & fees

Oct 21 - Oct 22

A room with a bed, a desk with a computer, a TV, and a fan.

A small, modern room with a kitchenette, a flat-screen TV mounted on the wall, and a herringbone-patterned wooden floor.

A bathroom with a black toilet, a black bidet, a sink with a black basin, and a towel rack with folded towels.

A room with a tiled floor, a flat-screen TV mounted on the wall, a small refrigerator, a microwave, and two bar stools.

3. PLEASANT HOSTAL PANAMA

24 de Diciembre

$44

$48 total

includes taxes & fees

Oct 23 - Oct 24

A modern cabin with a sloped roof, surrounded by trees, and a gravel path leading to the entrance.

A modern outdoor seating area with a hammock and two chairs, a wooden deck, and a glass wall offering a view of the surrounding trees.

A modern room with a bed, a small table, and a chair. There is a window with a view of trees and a hammock outside.

A modern kitchen with a built-in stove, a sink, and a shelf with dishes and a potted plant.

4. Tiny Cabin

Panamá

$134

$147 total

includes taxes & fees

Oct 19 - Oct 20

A hotel room with two single beds, a small table with a chair, a TV mounted on the wall, and a marble-patterned headboard.

A two-story building with a sign reading "HOTEL EXPRESS INN".

A rectangular swimming pool with blue tiles and a brick border.

A modern interior with a staircase, a seating area with a bench and tables, and a counter with a sign reading "NISATO".

5. Express Inn Panama International Airport Hostel

Tocumen Airport

$50

$54 total

includes taxes & fees

Oct 19 - Oct 20

A spacious lobby with a high ceiling, modern lighting fixtures, and a glass entrance leading to a lower level.

A swimming pool with a clear water surface, surrounded by a covered area with lounge chairs and a bar area.

A modern dining area with a wooden table and chairs, a built-in bookshelf, and a decorative hanging light fixture.

A modern bar area with a central island, bar stools, and a television mounted on the ceiling.

6. Crowne Plaza Panama Airport by IHG

Tocumen Airport

$122

$141 total

includes taxes & fees

Nov 5 - Nov 6

A bedroom with a large bed, a nightstand, a dresser, and decorative wall art.

A cozy living room with a television, a lamp, and a sofa.

A room with a cream-colored sofa with gold accents, a red carpet, and a small table with candles.

A multi-level interior with a wooden staircase, decorative lighting, and a blue wall.

7. ORHO Hotel Boutique 15 Minutes from PTY Airport

Tocumen Airport

$102

$133 total

includes taxes & fees

Oct 19 - Oct 20

A trampoline with a safety net in a grassy area with trees in the background.

A swimming pool with a bridge, surrounded by lush greenery and a seating area with tables and chairs.

A reception area with a receptionist, a statue, and a digital display.

A room with two beds, a desk, a chair, and a window with a view of greenery.

8. Riande Aeropuerto Hotel & Casino

Tocumen Airport

$108

$119 total

includes taxes & fees

Oct 26 - Oct 27

A building with a sign reading 'Lilia House' and a decorative wall with a sign stating 'Cada Familia tiene una.'

9. Swette Love 10 Minutes From the Airport Tocumen

Las Mañanitas

$56

$73 total

includes taxes & fees

Nov 1 - Nov 2

A buffet with various food items including fruits, juices, and cheeses.

A hotel reception area with a wooden reception desk, seating area with chairs and ottomans, and a large window providing natural light.

A gym with treadmills, weight machines, and dumbbells.

A modern hotel lobby with a sectional sofa, a glass coffee table, and a vibrant green wall mural.

10. Courtyard by Marriott Panama Metromall

San Antonio

$101

$111 total

includes taxes & fees

Nov 6 - Nov 7

A hotel entrance with a central water feature, seating areas, and potted plants.

A spacious lobby with a wooden ceiling, a central wooden table surrounded by potted plants, and a marble wall with a large window in the background.

A pool with a central water feature, surrounded by seating areas and potted plants.

The entrance of The Santa Maria with a covered walkway and a view of the interior.

11. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Juan Diaz

$312

$344 total

includes taxes & fees

Nov 8 - Nov 9

A rooftop pool with a city view, lounge chairs, and a clear sky.

A modern lobby with a curved grey sofa, a round coffee table, and an orange armchair. There are potted plants and a reception desk in the background.

A modern kitchen with a marble countertop, a refrigerator, and a dining area with a table set for two.

A modern gym with treadmills, weight machines, and exercise balls.

12. Corporate Stays Arcadia | Executive Furnished Apartments

Costa del Este

$91

$153 total

includes taxes & fees

Nov 1 - Nov 2

A rooftop pool with a city view, modern architecture, and outdoor seating.

A narrow street with multi-story buildings, balconies, and a central building with a red roof.

A modern hotel room with a large bed, a desk, and a view of the cityscape.

A high-rise building with a view of the ocean and a parking area with palm trees.

13. The Westin Panama

Costa del Este

$223

$245 total

includes taxes & fees

Nov 7 - Nov 8

A swimming pool with lounge chairs, surrounded by greenery and tall buildings in the background.

A gym with various exercise equipment, a brick wall, and a ceiling with wooden slats.

A modern building with the sign 'DOVILLE' and 'CIRCUNVENTENARIO' indicating a hotel or similar establishment.

A modern living room with a sofa, a dining table, and a staircase leading to an upper level.

14. Apex Executive Apartments - Dovle

Parque Lefevre

$109

$206 total

includes taxes & fees

Oct 22 - Oct 23

A modern outdoor swimming pool with a clear view of a tall building in the background.

A modern urban pathway lined with lush greenery and a pool, leading to a building with balconies and a clear sky.

A modern apartment with a living area, kitchen, and a staircase leading to an upper level.

A modern kitchen with a curved island, bar stools, pendant lighting, and wooden shelving with plants.

15. Dovle Residences by HMS-Preferred Member

San Francisco

$155

$170 total

includes taxes & fees

Nov 9 - Nov 10

A swimming pool with a modern design, surrounded by greenery and a building with large windows.

A modern building with a glass facade and the name 'DOVIL' prominently displayed.

A modern gym with treadmills, weight machines, and free weights.

A modern apartment with a living area, kitchen, and a balcony with a view.

16. Apartment for 3 in Panama With Pool and gym

San Francisco

$108

$153 total

includes taxes & fees

Oct 19 - Oct 20

A modern living room with a sofa, a coffee table with flowers, a TV, and a large window with a city view.

A dining area with a table set for four, large windows with a cityscape view, a small side table with a lamp, and a television on a stand.

A modern living room with a large window, a sofa, a coffee table, a TV on a wooden cabinet, and a dining table with chairs.

A bedroom with a large bed, a view through a sliding door, and two framed pictures on the wall.

17. Boutique Apartments Panamá Coco del Mar

San Francisco

$37

$181 total

includes taxes & fees

Oct 20 - Oct 21

A modern living room with a sofa, a dining table, and chairs, a wooden side table, and a large window with a city view.

A modern kitchen with a built-in microwave, a coffee maker, and a sink.

A rooftop pool area with lounge chairs, a large umbrella, and a city skyline view.

A modern interior with a dining area featuring round tables and colorful chairs, a kitchen area, and large windows offering a view of the city.

18. The Hub by Boutique Apartments

San Francisco

$32

$166 total

includes taxes & fees

Oct 20 - Oct 21

An elevator with a digital display showing the number 3, a sign above it reading 'PISO-3', and two safety signs on the wall.

A single bed with a dark blue mattress, a wooden headboard, and two pillows. There is a small wooden nightstand with drawers to the right of the bed. The room has plain white walls and a window with a sheer curtain.

A kitchen with a gas stove, a microwave, a trash bin, and a window.

A television mounted on a wall with a cityscape display, a small plant on a shelf, and a decorative light fixture.

19. Charming 3 Bedroom Apartment in San Miguelito, Panama City

José Domingo Espinar

$78

$106 total

includes taxes & fees

Oct 26 - Oct 27

A rooftop pool with lounge chairs, offering a city view.

A modern bedroom with a large window, a bed with a headboard, and a bedside table with a lamp.

A modern balcony with white chairs and a city view.

A spacious living room with a large window, a flat-screen TV, a sofa, and a coffee table.

20. Boutique Apartments Atlapa

San Francisco

$26

$138 total

includes taxes & fees

Oct 19 - Oct 20

View all properties

Go beyond your typical stay in La Mesa

Check out reviews of La Mesa hotels guests love

Riande Aeropuerto Hotel & Casino

Tocumen Airport

10/10 Exceptional

Roberto

ORHO Hotel Boutique 15 Minutes from PTY Airport

Tocumen Airport

10/10 Exceptional

Deborah

Crowne Plaza Panama Airport by IHG

Tocumen Airport

10/10 Exceptional

Ceci

Courtyard by Marriott Panama Metromall

San Antonio

10/10 Exceptional

Carlos

B&B Lodgings

24 de Diciembre

10/10 Exceptional

I had a wonderful experience staying at this hotel! Although it is a small hotel, the hospitality and personal attention were exceptional. The owner was absolutely amazing, welcoming, and attentive to every detail. The place was very clean, and I felt genuinely cared for throughout my stay. What impressed me the most was how thoughtful and helpful the owner was. They contacted me through WhatsApp to make sure I arrived at the correct location, offered to pick me up and drop me off, and even...

Diana

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Juan Diaz

10/10 Exceptional

John

Corporate Stays Arcadia | Executive Furnished Apartments

Costa del Este

10/10 Exceptional

This place is even more beautiful than the pictures! We stayed in unit 1508 and it felt brand new—super clean, stylish, and in a very safe area. I was nervous about booking last minute, but check-in was smooth. Irving greeted us and made us feel at home. Another huge plus is the location—you’re right across the street from a beautiful, modern mall with tons of great stores, cafes, and restaurants. There’s also a dog park directly across the street, as well as a family-friendly park nearby...

Dinita

A balcony with wicker chairs and a view of the cityscape.

A multi-story hotel with a modern facade, large windows, and a prominent entrance with a covered area.

A hotel room with a large bed, a desk with a lamp, a chair, and a view of a cityscape through a window.

A reception area with a marble wall, a 'Free Wireless Internet' sign, and a floral arrangement.

Ramada Plaza by Wyndham Panama Punta Pacifica

San Francisco

10/10 Exceptional

Theon

The Westin Panama

Costa del Este

10/10 Exceptional

Alvaro

A modern hotel with a prominent entrance, multiple floors, and a well-lit facade.

A modern interior with two escalators leading to upper floors, a prominent 'a loft Panama' sign, and a staircase with glass railings.

A modern lounge area with seating, a bar, and a staircase.

A modern rooftop pool with a view of high-rise buildings at night.

Aloft by Marriott Panama

San Francisco

10/10 Exceptional

Fernando

San Francisco by Wynwood House

San Francisco

10/10 Exceptional

Jelani

Boutique Apartments Panamá Coco del Mar

San Francisco

10/10 Exceptional

Spectacular view from the 31st floor of the city and partial ocean greeted us every morning, with a nice little patio to enjoy it from too. Three bedrooms, all with nice beds, plus a nice and large main and dining area. Everything worked well, including the air conditioning. Very safe residential building with front door security. It is not located in a main tourist area, but 5-10 min drive from best parts of Panama City. Area itself seemed safe. Food recommendation: one of the best restaurants...

Michael

Boutique Apartments Atlapa

San Francisco

10/10 Exceptional

Victor

A restaurant with a modern glass facade, wooden seating, and a sign indicating valet parking.

A modern high-rise building with a prominent 'Living' sign, large windows, and a sleek architectural design.

A modern living room with a TV, a sofa, a small coffee table, and a kitchen area in the background.

A modern living room with a flat-screen TV, a small white table with a plant, and a large glass door leading to an outdoor area.

Modern Apartments PH Living 73 SF

San Francisco

10/10 Exceptional

David

A modern living room with a sofa, a TV, a small table, and a balcony with a view of the city.

A modern interior with a glass pool, wooden panel walls, and a city view.

A rooftop swimming pool with modern lounge chairs and a city skyline in the background.

A modern interior with a glass floor, a sectional sofa, yellow cushions, and hanging plants.

Living 73 Panamá by Boutique Apartments

San Francisco

10/10 Exceptional

Lorenz

A modern living room with a sofa, coffee table, and a staircase leading to an upper floor.

A gym with various exercise equipment, including treadmills and weight machines.

A modern hotel room with a wooden desk, a chair, a bed, and a staircase.

A modern apartment with a kitchen, living area, and a balcony with a pool view.

Stylish Apartment With Pool Gym in Panama

San Francisco

8/10 Very good

Stepp

Frequently Asked Questions

What hotels do travelers like in La Mesa?

Guests like Crowne Plaza Panama Airport by IHG, Express Inn Panama International Airport Hostel and B&B Lodgings.

Can I book a refundable hotel in La Mesa?

If you need the flexibility to change your plans to La Mesa, most accommodations provide refundable* rates you can book. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.

What will the weather in La Mesa be like during my visit?

With an average temperature of 79°F during the coldest months, La Mesa is a great place to visit any time of year.

Why should I book my La Mesa hotel through Hotels.com?

There are plenty of reasons to book your La Mesa travel with us: our free cancellations on selected hotels* gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.