Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Get last-minute hotel deals in Kirksville and save more
Though Northeast Regional Medical Center might be what brings you to town, perhaps you'll have a chance to explore more of Kirksville while you are here.
Explore the lush trails and sparkling waters of Thousand Hills State Park, a natural oasis just minutes from town. Sip local vintages at Jacob's Vineyard & Winery before strolling through the historic campuses of Truman State and A.T. Still universities.
"We recently styed in this hotel. It is beside the main street so you can go anywhere very easily. Rooms are very clean, staffs are good. Internet was uninterrupted with good speed. Breakfast was all right but some Indian/Bangladeshi food should be included. I didn't check any laundry facilities there but if they have it, it can be wonderful. GOOD TO STAY. "
Holiday Inn Express & Suites Kirksville - University Area by IHG
10/10 Excellent
"Everything about our stay was great. The rooms were clean, the food was good, and the staff was amazing. Abby at the front desk was particularly kind and helpful. She went above and beyond to make our stay outstanding. "
"It wasn't completely booked and I stayed downstairs but a very active family was put in the room above me. Running, jumping is never ok in a 2nd floor room and some people are just too stupid to know that!"
"The staff is friendly. The hotel is clean and has large rooms. It is outdated but it's clear they are working on updating the rooms. There is no continental breakfast (which we knew from staying here on another trip) and the staff lets you know of the on-line error. "
Can I book a refundable accommodation in Kirksville?
If you want the flexibility to change your travel plans to Kirksville, most accommodations provide refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
Where should I stay in Kirksville if I want a reasonably priced accommodation?
Where can I stay in Kirksville if I want a vacation home instead of a traditional hotel?
Browse 7 vacation homes on our site. In addition, you can choose from 7 apartments.
What will the weather in Kirksville be like during my vacation?
July and August are typically the warmest months in Kirksville when the average temp is 73°F. January and February are the coldest months when the average temperature is 32°F. May and June are the months with the most rain.
Why should I book my Kirksville accommodation with Hotels.com?
There are lots of reasons to book your Kirksville trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.
Find out more about Kirksville
Find out more about Kirksville
If you're looking to discover somewhere new, look no further than Kirksville. Whether you're planning to stay for a night or for the week, the area around Kirksville has accommodations to fit every need. Search for hotels in Kirksville with Hotels.com by checking our online map. Our map displays the areas and neighborhoods around all Kirksville hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Kirksville hotel deals are here with our lowest price guarantee.