Hotels in South San Francisco
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Best Western Plus Grosvenor Airport Hotel
Best Western Plus Grosvenor Airport Hotel



Home2 Suites by Hilton San Francisco Airport North
Home2 Suites by Hilton San Francisco Airport North



DoubleTree by Hilton San Francisco South Airport Blvd
DoubleTree by Hilton San Francisco South Airport Blvd



Embassy Suites by Hilton San Francisco Airport Oyster Point
Embassy Suites by Hilton San Francisco Airport Oyster Point



Sonesta Select San Francisco Airport Oyster Point Waterfront
Sonesta Select San Francisco Airport Oyster Point Waterfront



Holiday Inn Express San Francisco-Airport North by IHG
Holiday Inn Express San Francisco-Airport North by IHG



Hilton Garden Inn San Francisco Arpt North
Hilton Garden Inn San Francisco Arpt North



La Quinta Inn & Suites by Wyndham San Francisco Airport N
La Quinta Inn & Suites by Wyndham San Francisco Airport N



Four Points by Sheraton Hotel & Suites San Francisco Airport
Four Points by Sheraton Hotel & Suites San Francisco Airport



Hampton Inn San Francisco Airport
Hampton Inn San Francisco Airport



AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront
AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront



Sonesta ES Suites San Francisco Airport Oyster Point Waterfront
Sonesta ES Suites San Francisco Airport Oyster Point Waterfront



Hotel Focus SFO
Hotel Focus SFO



Larkspur Landing Extended Stay Suites South San Francisco
Larkspur Landing Extended Stay Suites South San Francisco



Travelodge by Wyndham San Francisco Airport North
Travelodge by Wyndham San Francisco Airport North



Hotel Nova SFO
Hotel Nova SFO



Fairfield by Marriott Inn & Suites San Francisco Airport Oyster Point Area
Fairfield by Marriott Inn & Suites San Francisco Airport Oyster Point Area



Comfort Inn and Suites San Francisco Airport North
Comfort Inn and Suites San Francisco Airport North



Days Inn by Wyndham San Francisco S/Oyster Point Airport
Days Inn by Wyndham San Francisco S/Oyster Point Airport



Rodeway Inn South San Francisco Airport
Rodeway Inn South San Francisco AirportCheck out pet-friendly hotels in South San Francisco




Home2 Suites by Hilton San Francisco Airport North
Home2 Suites by Hilton San Francisco Airport North



DoubleTree by Hilton San Francisco South Airport Blvd
DoubleTree by Hilton San Francisco South Airport Blvd



Sonesta Select San Francisco Airport Oyster Point Waterfront
Sonesta Select San Francisco Airport Oyster Point Waterfront



Embassy Suites by Hilton San Francisco Airport Oyster Point
Embassy Suites by Hilton San Francisco Airport Oyster Point



La Quinta Inn & Suites by Wyndham San Francisco Airport N
La Quinta Inn & Suites by Wyndham San Francisco Airport N



Four Points by Sheraton Hotel & Suites San Francisco Airport
Four Points by Sheraton Hotel & Suites San Francisco Airport



Sonesta ES Suites San Francisco Airport Oyster Point Waterfront
Sonesta ES Suites San Francisco Airport Oyster Point WaterfrontYou may also like hotels with pools in South San Francisco




Embassy Suites by Hilton San Francisco Airport Oyster Point
Embassy Suites by Hilton San Francisco Airport Oyster Point



Sonesta ES Suites San Francisco Airport Oyster Point Waterfront
Sonesta ES Suites San Francisco Airport Oyster Point Waterfront



AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront
AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront



La Quinta Inn & Suites by Wyndham San Francisco Airport N
La Quinta Inn & Suites by Wyndham San Francisco Airport N



Travelodge by Wyndham San Francisco Airport North
Travelodge by Wyndham San Francisco Airport NorthGo beyond your typical stay in South San Francisco
Our prices for hotels in South San Francisco are cheapest in January
Price trends for hotels in South San Francisco
Top neighborhoods in South San Francisco



Downtown South San Francisco
Downtown South San Francisco buzzes with a blend of biotech innovation and cultural diversity. Corporate towers and colorful murals tell the story of this unique business hub. You'll find authentic taquerias, dim sum houses, and Filipino eateries nestled between modern office campuses along Grand Avenue. The neighborhood comes alive during weekdays when professionals fill its plazas and restaurants. Getting around is a breeze with nearby BART and Caltrain stations connecting you to San Francisco proper and beyond. Business hotels cater mostly to corporate travelers with practical amenities. The area quiets down after work hours, offering a genuine glimpse into Bay Area life away from tourist crowds.



Oyster Point
Oyster Point balances sleek biotech campuses with stunning San Francisco Bay views. The waterfront promenade offers perfect spots for watching waves crash against the shore or catching a beautiful sunset. Modern plazas feature public art installations while walking paths showcase both cutting-edge architecture and natural bay ecosystems. Business travelers appreciate the corporate hotels with meeting facilities and convenient access to office buildings. Dining options cater primarily to weekday lunch crowds, with most establishments closing early evening. The area is best explored by car, though waterfront paths provide scenic strolling opportunities away from the corporate hustle.

The East Side
The East Side delivers authentic local life away from San Francisco's tourist traps. Catch Bay views from San Bruno Point Park or explore diverse family-owned restaurants along Grand Avenue serving up killer tacos and pho. This residential neighborhood mixes Hispanic and Asian influences that shine through local markets and casual eateries. Budget travelers appreciate the affordable motels and extended-stay options that cost way less than downtown San Francisco. Buses connect to BART and Caltrain, though having wheels helps. Most spots close early, so plan your food adventures accordingly.

Paradise Valley
Paradise Valley offers a peaceful retreat from San Francisco's bustle while keeping you close to the action. This quiet residential neighborhood in South San Francisco balances suburban calm with convenient access to nearby attractions. Take a stroll through San Bruno Point Park or venture to local spots like K1 Speed for some indoor racing fun. Budget-friendly accommodations make Paradise Valley an appealing base for Bay Area exploration. The neighborhood's proximity to San Francisco International Airport and major highways ensures easy connections throughout the region. With ample street parking and minimal crowds, you'll appreciate this low-key alternative to the city's more hectic districts.
Top landmarks in South San Francisco
San Bruno Point Park
South San Francisco Convention Center
San Francisco Baking Institute
See's Candies
South San Francisco Hillside Sign
K1 Speed San Francisco
Sign Hill Park
Learn more about South San Francisco
Look beyond the iconic 'South San Francisco The Industrial City' sign crowning Sign Hill Park for a city with its own distinct identity. Grand Avenue serves up a global feast of family-run eateries where locals debate the merits of each dumpling house. San Bruno Mountain offers hiking trails with sweeping Bay views that explain why residents tolerate the fog. See's Candies factory tours satisfy sweet tooths, while K1 Speed delivers indoor racing thrills. The Convention Center hosts events that draw visitors who are surprised to discover this isn't simply San Francisco's southern neighborhood. Despite tripling in population since World War II, 'South City' maintains its working-class roots while embracing its role as a Peninsula destination in its own right.
See all hotels in South San Francisco
Check out reviews of South San Francisco hotels guests love
Hyatt Regency San Francisco
"The restaurant staff are of a quality not befitting a hotel of this class. The waiters do not pay the necessary attention to the customers. A busboy picked up a napkin that a previous customer had dropped on the floor, folded it, and placed it next to my plate."
Hotel Riu Plaza Fisherman's Wharf
"We enjoyed everything about this hotel, the close proximity to Pier 39 was great. The breakfast was delicious with many choices. Staff was helpful and friendly."
Hotel Focus SFO
"Todo muy bien"
Club Quarters Hotel in San Francisco
"Parking is convenient across the street $90 for 2 days (Embarcadero Center 1, 2, 3 and 4 options). Nice hotel, clean room, and great location."
