Hotels in Jackson

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Where to stay in Jackson?

A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.

A restaurant with a brick wall, a flat-screen TV, and a bar area.

A hotel room with two beds, a brick wall, and a wooden headboard.

A Drury Inn & Suites building with a traditional architectural style, featuring a covered entrance and multiple windows.

1. Drury Inn & Suites Jackson MO

Jackson

$82

$87 total

includes taxes & fees

Nov 1 - Nov 2

A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

A hotel room with two beds, a nightstand, a lamp, and a chair.

An outdoor patio with tables and chairs, a stone wall, and large windows.

A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.

2. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

$81

$87 total

includes taxes & fees

Nov 1 - Nov 2

A spacious lobby with large windows, comfortable seating, and a modern ceiling design.

A room with large windows, two red upholstered chairs, a small table, and a potted plant.

A breakfast bar with coffee machines, a cereal dispenser, and a fruit display.

A gym with treadmills, an elliptical, a bench, and a rack of dumbbells.

3. Comfort Suites Jackson-Cape Girardeau

Jackson

$76

$82 total

includes taxes & fees

Oct 25 - Oct 26

A kitchen with dark wooden cabinets, a stainless steel refrigerator, a black stove, a microwave, and a sink.

A bathroom with a granite countertop sink, a mirror, two hair dryers mounted on the wall, and a trash bin.

A hotel room with two beds, a wooden dresser, a bathroom with a shower, and a kitchen area.

A trophy labeled "Town House Inn" with "Cape Girardeau County, Missouri" and "2025" on it.

4. Town House Inn

Jackson

$71

$77 total

includes taxes & fees

Oct 5 - Oct 6

A modern retail area with a display of local items and snacks.

A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.

A hotel room with two beds, a desk, a chair, a TV, and a window with a view.

A modern indoor seating area with blue sofas and tables, a patterned carpet, and large windows offering a view of the outdoors.

5. Tru By Hilton Cape Girardeau

Cape Girardeau

$89

$102 total

includes taxes & fees

Oct 8 - Oct 9

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.

A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.

An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.

A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.

6. Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

$100

$113 total

includes taxes & fees

Oct 5 - Oct 6

A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.

A breakfast setting with waffles, scrambled eggs, toast, a glass of orange juice, and a white mug on a table with a green placemat.

A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.

A bowl of cereal with raisins and milk, a half orange, and a sandwich on a table with a yellow napkin.

7. Drury Inn & Suites Cape Girardeau

Cape Girardeau

$91

$103 total

includes taxes & fees

Oct 14 - Oct 15

A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.

A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.

A Dear Tree Inn building with a covered entrance and a clear sky at dusk.

A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.

8. Pear Tree Inn Cape Girardeau West

Cape Girardeau

$72

$81 total

includes taxes & fees

Oct 11 - Oct 12

A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.

A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.

A reception area with a wooden reception desk, a glass door leading to a storage room, and a decorative wall piece.

An indoor swimming pool with lounge chairs and tables, large windows, and a view of the outside.

9. Fairfield Inn & Suites by Marriott Cape Girardeau

Cape Girardeau

$101

$114 total

includes taxes & fees

Oct 8 - Oct 9

A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.

A reception desk with a green wall, a wooden door, and a sign that reads 'QUALITY INN.'

A hotel room with a large bathtub, a bed with a wooden headboard, a nightstand with a lamp, and a painting of a building on the wall.

A hotel room with a flat-screen TV, a microwave, a sofa, a lamp, and a window with curtains.

10. Quality Inn Cape Girardeau North

Cape Girardeau

$59

$67 total

includes taxes & fees

Nov 1 - Nov 2

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.

An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.

A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.

A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.

11. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Cape Girardeau

$101

$115 total

includes taxes & fees

Oct 4 - Oct 5

A spacious lobby with a curved staircase, large windows, and a seating area with a rug.

A hotel room with two beds, a desk, a chair, and a view of the city.

A modern outdoor seating area with a fire feature, a stone wall, and a view of the sunset.

A modern bar area with a herringbone patterned wall, a long counter with bar stools, and a variety of bottles and glasses.

12. The Riverview

Cape Girardeau

$114

$129 total

includes taxes & fees

Oct 5 - Oct 6

A spacious dining area with high ceilings, large windows, and modern lighting fixtures.

A gym with exercise equipment, a treadmill, and a wall-mounted TV.

A large indoor swimming pool with clear blue water, surrounded by tiled flooring and blue walls.

An outdoor patio with stone walls, wicker furniture, and large windows.

13. Hampton Inn Cape Girardeau I 55 East

Cape Girardeau

$106

$119 total

includes taxes & fees

Oct 8 - Oct 9

A spacious lobby with marble flooring, elegant seating, and a grand staircase.

A lobby with seating areas, a reception desk, and a bar.

A Courtyard by Marriott hotel with a modern brick facade, large windows, and a covered entrance area.

A modern hotel lobby with a framed advertisement for breakfast at the new Bistro, a seating area with sofas and a coffee table, and a decorative mirror reflecting the space.

14. Courtyard by Marriott Cape Girardeau Downtown

Cape Girardeau

$125

$142 total

includes taxes & fees

Oct 12 - Oct 13

A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.

A hotel entrance with a large tree, a well-maintained garden with various plants and flowers, and a parking lot.

A hotel patio with a gazebo, outdoor seating, and a view of the road.

An indoor swimming pool with tiled flooring, a seating area with chairs, and a staircase leading to a door.

15. Candlewood Suites Cape Girardeau by IHG

Cape Girardeau

$85

$101 total

includes taxes & fees

Oct 11 - Oct 12

A hotel room with a bed, desk, chair, television, and two wall-mounted lamps.

A bathroom with a marble wall and a white bathtub.

A hotel room with a kitchenette, a bed, a dining table with chairs, a TV mounted on the wall, and a dresser.

A motel with multiple floors, a parking lot, and a staircase leading to the upper floors.

16. Town House Inn Cape Giradreau

Cape Girardeau

$70

$82 total

includes taxes & fees

Oct 4 - Oct 5

A living room with a blue wall, a fireplace, a sofa, and a chair.

A hotel room with two beds, a vanity with a mirror, a chair, and a dresser.

A sign for EC REED'S MERCANTILE & HOTEL with a geometric design.

A bar area with stools and a counter where a bartender is serving drinks.

17. EC Reed's Mercantile and Hotel

Marble Hill

$117

$127 total

includes taxes & fees

Oct 4 - Oct 5

A rustic cabin-style lodging with a covered porch, picnic tables, and a fire pit.

A playground with a wooden playhouse, a slide, and two animal-shaped swings.

A swimming pool with a small water slide, surrounded by lounge chairs and umbrellas.

A lakeside RV resort with wooden cabins, a picnic area, and a reflection in the water.

18. Perryville RV Resort

Perryville

$66

$76 total

includes taxes & fees

Oct 6 - Oct 7

A rustic interior with exposed brick walls, wooden railings, and a hanging floral chandelier.

A building with a dark exterior, a large window, and a sign that reads "The Atrium."

A building with a sign that reads "The Atrium Boutique Hotel".

A fireplace with a decorative mantel, a framed sign, and a small table with plants.

19. The Atrium - A Boutique Hotel

Perryville

$84

$170 total

includes taxes & fees

Oct 2 - Oct 3

A hotel room with a large bathtub, a sofa, a small table, a TV, and a window with curtains.

A hotel room with a large bed, a desk with a chair, a television, and a small table with a lamp.

A hotel room with a kitchenette, a large mirror, a sofa, and a patterned carpet.

A hotel lobby with two sofas, a coffee table, lamps, and a large window with a plant.

20. Super 8 by Wyndham Perryville

Perryville

$70

$80 total

includes taxes & fees

Oct 11 - Oct 12

View all properties

Go beyond your typical stay in Jackson

Pet friendly

Pool

Family friendly

Our prices for hotels in Jackson are cheapest in December

Top landmarks in Jackson

Litz Park

8.6/10 (14 reviews)

Litz Park is worth a visit, located 0.8 mi (1.3 km) from central Jackson.

See properties

Lake Boutin

Lake Boutin is 11 mi (17.6 km) from central Jackson, why not stop by during your stay.

See properties

Indian Creek Wild Area

Indian Creek Wild Area is 11.2 mi (18 km) from central Jackson, why not stop by during your stay.

See properties

Vancill Hollow Natural Area

Vancill Hollow Natural Area is 11.6 mi (18.7 km) from central Jackson, why not stop by during your stay.

See properties

Learn more about Jackson

Jackson is well-known for its attractions such as Trail of Tears State Park and Mississippi River. This family-friendly city has something for everyone including restaurants as well as sights like Lake Boutin and Indian Creek Wild Area. All are within a rural setting.

See all hotels in Jackson

A historic building with a dome and columns, surrounded by trees and a paved walkway.

Check out reviews of Jackson hotels guests love

Drury Inn & Suites Jackson MO

10/10 Excellent

"One of the best hotels I have stayed in."

Quality Inn Cape Girardeau North

10/10 Excellent

"Great place great breakfast great room staff was great"

Candlewood Suites Cape Girardeau by IHG

10/10 Excellent

"trodo estubo excelente gracias por sus servicios"

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

10/10 Excellent

"Clean rooms. Nice breakfast. Very nice staff."

Drury Inn & Suites Cape Girardeau

10/10 Excellent

"Upgraded to a 2 room suite. Rey nice room lots of storage. Would definitely stay here again."

Holiday Inn Express & Suites Perryville by IHG

10/10 Excellent

"Check in and check out for 25 rooms was a breeze. Hotel room cards were ready as soon as we approached the hotel counter."

Courtyard by Marriott Cape Girardeau Downtown

10/10 Excellent

"Very nice! Bed was comfortable and room had a very large bathroom and shower. Towels were thick and fluffy. Enjoyed having a bar downstairs with a fun friendly staff. Will stay there again when I’m coming through."

Frequently asked questions

What accommodations do travelers like in Jackson?

Guests like La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau, Drury Inn & Suites Jackson MO and Comfort Suites Jackson-Cape Girardeau.

Can I book a refundable hotel in Jackson?

If you need the flexibility to change your travel plans to Jackson, most properties offer refundable* rates you can book. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

Where should I consider staying in Jackson if I'm looking for a budget-friendly accommodation?

Comfort Suites Jackson-Cape Girardeau is an accommodation you might want to consider that'll save you money.

Where can I stay in Jackson if I want a vacation home instead of a hotel?

Browse 5 vacation homes on our site.

What will the weather in Jackson be like during my visit?

July and August are typically the warmest months in Jackson when the average temp is 76°F. January and February are the coldest months when the average temperature is 40°F. April and March are the months with the most rain.

Why should I book my Jackson hotel through Hotels.com?

There are lots of reasons to book your Jackson trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Keep exploring

More ways to book

Book Hotels in Jackson on Hotels.com

Hotels in Jackson

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Where to stay in Jackson?

1. Drury Inn & Suites Jackson MO

2. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3. Comfort Suites Jackson-Cape Girardeau

4. Town House Inn

5. Tru By Hilton Cape Girardeau

6. Drury Plaza Hotel Cape Girardeau Conference Center

7. Drury Inn & Suites Cape Girardeau

8. Pear Tree Inn Cape Girardeau West

9. Fairfield Inn & Suites by Marriott Cape Girardeau

10. Quality Inn Cape Girardeau North

11. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

12. The Riverview

13. Hampton Inn Cape Girardeau I 55 East

14. Courtyard by Marriott Cape Girardeau Downtown

15. Candlewood Suites Cape Girardeau by IHG

16. Town House Inn Cape Giradreau

17. EC Reed's Mercantile and Hotel

18. Perryville RV Resort

19. The Atrium - A Boutique Hotel

20. Super 8 by Wyndham Perryville

Go beyond your typical stay in Jackson

Price trends for hotels in Jackson

Typical weather for Jackson

Top landmarks in Jackson

Litz Park

Lake Boutin

Indian Creek Wild Area

Vancill Hollow Natural Area

Learn more about Jackson

Check out reviews of Jackson hotels guests love

Drury Inn & Suites Jackson MO

Quality Inn Cape Girardeau North

Candlewood Suites Cape Girardeau by IHG

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Drury Inn & Suites Cape Girardeau

Holiday Inn Express & Suites Perryville by IHG

Courtyard by Marriott Cape Girardeau Downtown

Frequently asked questions

Keep exploring