Hotels in Panama City

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight
Sep 28 - Sep 29
Tomorrow
Sep 29 - Sep 30
This weekend
Oct 2 - Oct 4
Next weekend
Oct 9 - Oct 11

Where to stay in Panama City?

A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.
A modern living room with a sofa set, a coffee table, and a dining area with chairs and a table.
A spacious lobby with a central seating area, a chandelier, and a modern ceiling design.
A hotel room with a bed, a TV, a desk, and a view of the cityscape through a window.

1. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
Bella Vista
$138
$151 total
includes taxes & fees
Oct 25 - Oct 26
Hotel Riu Plaza Panama
A high-rise building with a modern architectural design, featuring a grid of windows and balconies.
A modern spa area with a hot tub, seating, and a city view.
An escalator in a hotel lobby with a patterned wall and framed artwork.
A rooftop lounge with modern seating and a panoramic city view.

2. Megapolis Hotel Panamá

Megapolis Hotel Panamá
San Francisco
$161
$177 total
includes taxes & fees
Sep 30 - Oct 1
Megapolis Hotel Panamá
A balcony with wicker chairs and a view of the cityscape.
A multi-story hotel with a modern facade, large windows, and a prominent entrance with a covered area.
A rooftop pool area with a view of high-rise buildings in the background.
A hotel room with a large bed, a desk with a lamp, a chair, and a view of a cityscape through a window.

3. Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
San Francisco
$106
$117 total
includes taxes & fees
Sep 30 - Oct 1
Ramada Plaza by Wyndham Panama Punta Pacifica
A rooftop pool with sun loungers and a city skyline in the background.
A long, narrow hallway with a wooden floor and light-colored walls.
A modern hotel room with a large bed, a desk, a chair, and a wardrobe.
A bar area with a curved counter, multiple screens, and a patterned carpet.

4. Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
Bella Vista
$71
$133 total
includes taxes & fees
Sep 30 - Oct 1
Waymore Hotel Spa & Casino
A hotel named PRINCIPE with a modern facade and large glass windows.
A swimming pool with lounge chairs and a table.
A hotel lobby with a reception desk, seating area, and a visible sign for 'PRINCIPES HOTEL & SQUITES'.
A hotel reception area with a modern design, featuring a reception desk, white chairs, and a visible fire feature.

5. Principe Hotel and Suites

Principe Hotel and Suites
Bella Vista
$59
$65 total
includes taxes & fees
Sep 30 - Oct 1
Principe Hotel and Suites
A modern hotel with a prominent entrance, multiple floors, and a well-lit facade.
A spacious lobby with a pool table, comfortable seating areas, and a bar with a variety of beverages.
A modern rooftop pool with a view of high-rise buildings at night.
A modern interior with two escalators leading to upper floors, a prominent 'a loft Panama' sign, and a staircase with glass railings.

6. Aloft by Marriott Panama

Aloft by Marriott Panama
San Francisco
$132
$146 total
includes taxes & fees
Oct 9 - Oct 10
Aloft by Marriott Panama
A modern lobby with a chandelier, seating area, reception desk, and a staircase.
A dining area with a glass table, wicker chairs, a plate of fruit, and a cocktail glass.
A lobby with a reception desk, seating area, and a bar.
A hotel dining area with wicker chairs, a bar counter, and pendant lighting.

7. The Executive Hotel

The Executive Hotel
Bella Vista
$89
$98 total
includes taxes & fees
Oct 21 - Oct 22
The Executive Hotel
A pool area with lounge chairs and umbrellas, surrounded by greenery and a multi-story building in the background.
A modern interior with a central seating area, potted plants, and a staircase.
A spacious lobby with a curved ceiling, a central staircase, and a reception desk.
A modern building with a sign reading 'HYATT REGENCY.'

8. Hyatt Regency Panama City

Hyatt Regency Panama City
Bella Vista
$187
$206 total
includes taxes & fees
Oct 11 - Oct 12
Hyatt Regency Panama City
A modern building with a glass facade, a curved structure, and a flat roof.
A modern hotel room with a large bed, a TV, a desk, and a view of the city.
A spacious lobby with red and blue seating, a large circular wall feature, and a modern design with concrete elements.
A modern hotel room with a large bed, a desk with a flat-screen TV, a city view, and a large painting on the wall.

9. Decapolis Hotel Panama City

Decapolis Hotel Panama City
San Francisco
$111
$122 total
includes taxes & fees
Oct 12 - Oct 13
Decapolis Hotel Panama City
A resort with a large swimming pool, thatched-roof structures, and palm trees.
A hotel room with a large bed, a chair, a desk, and a view of the ocean.
A resort with a pool, palm trees, and a building with a red roof.
An outdoor dining area with tables and chairs, overlooking a body of water and a forested island.

10. Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive
Veracruz
$278
$278 total
includes taxes & fees
Oct 1 - Oct 2
Dreams Playa Bonita Panama - All Inclusive
A poolside area with lounge chairs and a view of the ocean.
A modern building with a symmetrical facade, multiple balconies, and a central atrium with lighting.
A modern hotel room with a large bed, a chair, a nightstand with a lamp, and a view of the cityscape at dusk.
A modern bathroom with a large bathtub, two sinks, and a glass-enclosed shower area with a city view.

11. JW Marriott Panama

JW Marriott Panama
San Francisco
$255
$281 total
includes taxes & fees
Oct 17 - Oct 18
JW Marriott Panama
A modern lobby with a glass railing, a central staircase, and a view of the cityscape through large windows.
A modern hotel room with a large window offering a city view, a chandelier, and a cozy seating area.
A modern living area with a sofa, chairs, and a coffee table. There is a view of the city through large windows.
A spacious lobby with a staircase, seating area, and a bar.

12. Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
San Francisco
$141
$155 total
includes taxes & fees
Oct 17 - Oct 18
Las Americas Golden Tower Panama
A covered outdoor seating area with a view of a city skyline and water.
A nighttime view of a high-rise building complex with illuminated windows and a prominent red-lit structure.
A hotel room with two beds, a desk, and a large window offering a city view.
A cityscape with high-rise buildings, a waterfront, and a modern sculpture.

13. Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
San Francisco
$108
$108 total
includes taxes & fees
Oct 12 - Oct 13
Plaza Paitilla Inn Hotel
A multi-story hotel with a Marriott sign, surrounded by high-rise buildings and a busy street with cars.
A modern lounge area with a wooden partition, a bar with a variety of bottles, and a seating area with chairs.
A modern reception area with a wooden panel wall, a sign indicating 'Marriott Bonvoy', and three reception desks with digital displays.
A modern cafe with wooden tables and chairs, large windows, and decorative vases on shelves.

14. Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall
San Francisco
$122
$135 total
includes taxes & fees
Oct 17 - Oct 18
Courtyard by Marriott Panama Multiplaza Mall
A modern hotel room with a sofa, a coffee table, a TV mounted on the wall, and a dining area with a table and chairs.
A modern hotel entrance with a prominent 'Renaissance Hotel' sign, a well-lit outdoor area with a wooden structure, and a staircase leading to the upper floors.
A modern lobby with a staircase, marble flooring, and large windows with tropical plants.
An indoor swimming pool with lounge chairs and red chairs, surrounded by lush greenery and a modern interior design.

15. Renaissance Panama City Hotel

Renaissance Panama City Hotel
Bella Vista
$127
$140 total
includes taxes & fees
Oct 9 - Oct 10
Renaissance Panama City Hotel
A modern hotel entrance with a prominent 'NOVOTEL' sign, large glass windows, and geometric light patterns on the facade.
A bar area with a variety of liquor bottles, a counter, and seating with tables and chairs.
A spacious lobby with large windows, a curved ceiling, and a seating area with a patterned rug.
A hotel room with a bed and a view of a cityscape through sheer curtains.

16. Novotel Panama City

Novotel Panama City
Bella Vista
$93
$102 total
includes taxes & fees
Oct 18 - Oct 19
Novotel Panama City
A modern restaurant with large windows offering a city view, warm lighting, and contemporary furniture.
A high-rise building with a rooftop pool area, surrounded by other buildings.
A modern living room with a city view, featuring a purple accent wall, a white sofa, and a glass table.
A modern hotel room with a large bed, a desk, a chair, and a view of the cityscape.

17. W Panama

W Panama
Bella Vista
$239
$263 total
includes taxes & fees
Oct 17 - Oct 18
W Panama
A rooftop pool with lounge chairs and a city skyline view.
A gym with treadmills, elliptical machines, free weights, and a bench.
A person seated on a wicker chair with a view of a cityscape through large windows.
A hotel room with a bed, a sofa, an ottoman, a wall-mounted lamp, and a wardrobe.

18. Hotel Dann Carlton Marinn Place Panama Financial District

Hotel Dann Carlton Marinn Place Panama Financial District
Bella Vista
$82
$118 total
includes taxes & fees
Oct 27 - Oct 28
Hotel Dann Carlton Marinn Place Panama Financial District
A modern hotel pool area with lounge chairs and a clear view of the ocean.
A marina with boats docked, a city skyline with illuminated buildings, and a visible moon in the sky.
A spacious lobby with a large seating area, a glass display case with bottles, and a view of the city at night.
A modern bar area with seating and a view of the city.

19. Hilton Panama

Hilton Panama
Bella Vista
$247
$272 total
includes taxes & fees
Oct 10 - Oct 11
Hilton Panama
A rooftop pool with lounge chairs and a city skyline view.
A hotel room with a large bed, a desk, a chair, a sofa, and a TV mounted on the wall.
The exterior of AC Hotel Panama with a modern glass entrance, visible seating area outside, and signage indicating it is a Marriott hotel.
A bar area with a counter, multiple shelves of bottles, bar stools, and a tufted leather wall.

20. AC Hotel by Marriott Panama City

AC Hotel by Marriott Panama City
Bella Vista
$114
$125 total
includes taxes & fees
Sep 30 - Oct 1
AC Hotel by Marriott Panama City
View all properties

Get last-minute hotel deals in Panama City and save more

Sign in to unlock great savings.
A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.
A modern living room with a sofa set, a coffee table, and a dining area with chairs and a table.
A spacious lobby with a central seating area, a chandelier, and a modern ceiling design.
A hotel room with a bed, a TV, a desk, and a view of the cityscape through a window.

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
Bella Vista
$187 off
$151
per night
$332 total
includes taxes & fees
Hotel Riu Plaza Panama
A high-rise building with a modern architectural design, featuring a grid of windows and balconies.
A modern spa area with a hot tub, seating, and a city view.
An escalator in a hotel lobby with a patterned wall and framed artwork.
A rooftop lounge with modern seating and a panoramic city view.

Megapolis Hotel Panamá

Megapolis Hotel Panamá
San Francisco
$665 off
$162
per night
$357 total
includes taxes & fees
Megapolis Hotel Panamá
A rooftop pool with sun loungers and a city skyline in the background.
A long, narrow hallway with a wooden floor and light-colored walls.
A modern hotel room with a large bed, a desk, a chair, and a wardrobe.
A bar area with a curved counter, multiple screens, and a patterned carpet.

Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
Bella Vista
$64
per night
$251 total
includes taxes & fees
Waymore Hotel Spa & Casino
A rooftop pool with lounge chairs and a city skyline view.
A gym with treadmills, elliptical machines, free weights, and a bench.
A person seated on a wicker chair with a view of a cityscape through large windows.
A hotel room with a bed, a sofa, an ottoman, a wall-mounted lamp, and a wardrobe.

Hotel Dann Carlton Marinn Place Panama Financial District

Hotel Dann Carlton Marinn Place Panama Financial District
Bella Vista
$88
per night
$248 total
includes taxes & fees
Sign in for extra savings
Hotel Dann Carlton Marinn Place Panama Financial District
A multi-story building with balconies, arched windows, and decorative railings.
A multi-level atrium with wooden staircases, seating areas, and a decorative ceiling.
A spacious lobby with a wooden staircase, multiple seating areas, and a reception desk.
A rooftop swimming pool with lounge chairs, potted plants, and a view of a city skyline including a prominent building with a dome.

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
Casco Viejo
$491 off
$213
per night
$470 total
includes taxes & fees
Central Hotel Panama Casco Viejo
A hotel named PRINCIPE with a modern facade and large glass windows.
A swimming pool with lounge chairs and a table.
A hotel lobby with a reception desk, seating area, and a visible sign for 'PRINCIPES HOTEL & SQUITES'.
A hotel reception area with a modern design, featuring a reception desk, white chairs, and a visible fire feature.

Principe Hotel and Suites

Principe Hotel and Suites
Bella Vista
$41 off
$59
per night
$130 total
includes taxes & fees
Principe Hotel and Suites
A modern lobby with a chandelier, seating area, reception desk, and a staircase.
A dining area with a glass table, wicker chairs, a plate of fruit, and a cocktail glass.
A lobby with a reception desk, seating area, and a bar.
A hotel dining area with wicker chairs, a bar counter, and pendant lighting.

The Executive Hotel

The Executive Hotel
Bella Vista
$30 off
$97
per night
$213 total
includes taxes & fees
The Executive Hotel
A restaurant with booths, a neon-lit red wall, hanging plants, and pendant lights.
A hotel room with a bed, a sofa, a coffee table, a desk, and a large window with a city view.
Rooftop pool
A hotel room with a large bed, a desk, a chair, a sofa, and a view of the cityscape.

Hotel Mio Panama

Hotel Mio Panama
Bella Vista
$60
per night
$132 total
includes taxes & fees
Hotel Mio Panama
A spacious outdoor patio with wicker furniture, potted plants, and umbrellas providing shade.
A dimly lit restaurant with wooden decor, tables, and chairs arranged for dining.
A hotel with a covered entrance, multiple windows, and a balcony with plants.
A modern hotel lobby with beige sofas, marble flooring, and a reception desk.

Hotel San Felipe

Hotel San Felipe
Casco Viejo
$119 off
$153
per night
$337 total
includes taxes & fees
Hotel San Felipe
A modern lobby with a glass railing, a central staircase, and a view of the cityscape through large windows.
A modern hotel room with a large window offering a city view, a chandelier, and a cozy seating area.
A modern living area with a sofa, chairs, and a coffee table. There is a view of the city through large windows.
A spacious lobby with a staircase, seating area, and a bar.

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
San Francisco
$156
per night
$343 total
includes taxes & fees
Las Americas Golden Tower Panama
A rooftop pool with clear blue water, surrounded by palm trees and a city skyline in the background.
A reception area with a modern design, featuring a large wooden panel with abstract carvings, a blue marble section, and a vibrant artificial flower wall.
A modern hotel room with a large bed, a wardrobe, a desk with a chair, and a decorative wall piece.
A restaurant with wooden tables and chairs, hanging plants, and circular wall decorations.

Gran Evenia Panama

Gran Evenia Panama
Bella Vista
$20 off
$91
per night
$201 total
includes taxes & fees
Gran Evenia Panama
A modern building with a glass facade, a curved structure, and a flat roof.
A modern hotel room with a large bed, a TV, a desk, and a view of the city.
A spacious lobby with red and blue seating, a large circular wall feature, and a modern design with concrete elements.
A modern hotel room with a large bed, a desk with a flat-screen TV, a city view, and a large painting on the wall.

Decapolis Hotel Panama City

Decapolis Hotel Panama City
San Francisco
$112
per night
$246 total
includes taxes & fees
Decapolis Hotel Panama City
A restaurant with multiple dining tables, chairs, and a central water feature.
A historic building with ornate stonework and a balcony with plants.
A bar area with multiple seating options, a bar counter, and a fireplace.
A modern living room with a sofa, a coffee table, and a TV mounted on the wall.

Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
Casco Viejo
$109 off
$310
per night
$682 total
includes taxes & fees
Hotel La Compañía Casco Antiguo
A covered outdoor seating area with a view of a city skyline and water.
A nighttime view of a high-rise building complex with illuminated windows and a prominent red-lit structure.
A hotel room with two beds, a desk, and a large window offering a city view.
A cityscape with high-rise buildings, a waterfront, and a modern sculpture.

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
San Francisco
$135
per night
$297 total
includes taxes & fees
Plaza Paitilla Inn Hotel
A conference room with a large table, chairs, a potted plant, and a curtain backdrop.
A buffet setup with various dishes and a decorative plant.
A dining area with a round table, chairs, and a view of a swimming pool and palm trees.
An outdoor dining area with tables and umbrellas, a person playing a saxophone, and a building with illuminated windows in the background.

Riande Urban Hotel

Riande Urban Hotel
Bella Vista
$108
per night
$238 total
includes taxes & fees
Riande Urban Hotel
A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.
A modern living room with a sofa set, a coffee table, and a dining area with chairs and a table.
A spacious lobby with a central seating area, a chandelier, and a modern ceiling design.
A hotel room with a bed, a TV, a desk, and a view of the cityscape through a window.

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
Bella Vista
$197 off
$159
per night
$349 total
includes taxes & fees
Hotel Riu Plaza Panama
A rooftop pool with sun loungers and a city skyline in the background.
A long, narrow hallway with a wooden floor and light-colored walls.
A modern hotel room with a large bed, a desk, a chair, and a wardrobe.
A bar area with a curved counter, multiple screens, and a patterned carpet.

Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
Bella Vista
$64
per night
$251 total
includes taxes & fees
Waymore Hotel Spa & Casino
A high-rise building with a modern architectural design, featuring a grid of windows and balconies.
A modern spa area with a hot tub, seating, and a city view.
An escalator in a hotel lobby with a patterned wall and framed artwork.
A rooftop lounge with modern seating and a panoramic city view.

Megapolis Hotel Panamá

Megapolis Hotel Panamá
San Francisco
$190
per night
$417 total
includes taxes & fees
Megapolis Hotel Panamá
A rooftop pool with lounge chairs and a city skyline view.
A gym with treadmills, elliptical machines, free weights, and a bench.
A person seated on a wicker chair with a view of a cityscape through large windows.
A hotel room with a bed, a sofa, an ottoman, a wall-mounted lamp, and a wardrobe.

Hotel Dann Carlton Marinn Place Panama Financial District

Hotel Dann Carlton Marinn Place Panama Financial District
Bella Vista
$96
per night
$266 total
includes taxes & fees
Sign in for extra savings
Hotel Dann Carlton Marinn Place Panama Financial District
A restaurant with multiple dining tables, chairs, and a central water feature.
A historic building with ornate stonework and a balcony with plants.
A bar area with multiple seating options, a bar counter, and a fireplace.
A modern living room with a sofa, a coffee table, and a TV mounted on the wall.

Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
Casco Viejo
$99 off
$280
per night
$615 total
includes taxes & fees
Hotel La Compañía Casco Antiguo
A spacious outdoor patio with wicker furniture, potted plants, and umbrellas providing shade.
A dimly lit restaurant with wooden decor, tables, and chairs arranged for dining.
A hotel with a covered entrance, multiple windows, and a balcony with plants.
A modern hotel lobby with beige sofas, marble flooring, and a reception desk.

Hotel San Felipe

Hotel San Felipe
Casco Viejo
$119 off
$153
per night
$337 total
includes taxes & fees
Hotel San Felipe
A hotel named PRINCIPE with a modern facade and large glass windows.
A swimming pool with lounge chairs and a table.
A hotel lobby with a reception desk, seating area, and a visible sign for 'PRINCIPES HOTEL & SQUITES'.
A hotel reception area with a modern design, featuring a reception desk, white chairs, and a visible fire feature.

Principe Hotel and Suites

Principe Hotel and Suites
Bella Vista
$41 off
$59
per night
$130 total
includes taxes & fees
Principe Hotel and Suites
A modern lobby with a glass railing, a central staircase, and a view of the cityscape through large windows.
A modern hotel room with a large window offering a city view, a chandelier, and a cozy seating area.
A modern living area with a sofa, chairs, and a coffee table. There is a view of the city through large windows.
A spacious lobby with a staircase, seating area, and a bar.

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
San Francisco
$156
per night
$343 total
includes taxes & fees
Las Americas Golden Tower Panama
A restaurant with booths, a neon-lit red wall, hanging plants, and pendant lights.
A hotel room with a bed, a sofa, a coffee table, a desk, and a large window with a city view.
Rooftop pool
A hotel room with a large bed, a desk, a chair, a sofa, and a view of the cityscape.

Hotel Mio Panama

Hotel Mio Panama
Bella Vista
$59
per night
$129 total
includes taxes & fees
Hotel Mio Panama
A covered outdoor seating area with a view of a city skyline and water.
A nighttime view of a high-rise building complex with illuminated windows and a prominent red-lit structure.
A hotel room with two beds, a desk, and a large window offering a city view.
A cityscape with high-rise buildings, a waterfront, and a modern sculpture.

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
San Francisco
$133
per night
$292 total
includes taxes & fees
Plaza Paitilla Inn Hotel
A conference room with a large table, chairs, a potted plant, and a curtain backdrop.
A buffet setup with various dishes and a decorative plant.
A dining area with a round table, chairs, and a view of a swimming pool and palm trees.
An outdoor dining area with tables and umbrellas, a person playing a saxophone, and a building with illuminated windows in the background.

Riande Urban Hotel

Riande Urban Hotel
Bella Vista
$95
per night
$208 total
includes taxes & fees
Riande Urban Hotel
A modern building with a glass facade, a curved structure, and a flat roof.
A modern hotel room with a large bed, a TV, a desk, and a view of the city.
A spacious lobby with red and blue seating, a large circular wall feature, and a modern design with concrete elements.
A modern hotel room with a large bed, a desk with a flat-screen TV, a city view, and a large painting on the wall.

Decapolis Hotel Panama City

Decapolis Hotel Panama City
San Francisco
$123
per night
$271 total
includes taxes & fees
Decapolis Hotel Panama City
A modern living room with a sofa, round black ottomans, and a vase of flowers. A cityscape is visible through the window.
A cozy outdoor seating area with a wooden bench and white tables, surrounded by lush greenery and potted plants.
A person performing a yoga pose in a living room with a large window and a sofa.
A rooftop swimming pool with a cityscape view, glass railings, and a modern architectural design.

Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
Bella Vista
$215
per night
$472 total
includes taxes & fees
Bristol Panama, a Registry Collection Hotel
A rooftop bar with a city skyline view, outdoor seating, and a bar area with bottles and glasses.
A hotel room with a large bed, a painting on the wall, a door, and a small table with a lamp.
A modern living room with a purple wall, two abstract paintings, a white sofa with colorful cushions, a wooden coffee table with books and bottles, and patterned floor tiles.
A room with a kitchenette, a sofa, a bed, and a mural with the phrase "Just Breathe".

Tantalo Hotel

Tantalo Hotel
Casco Viejo
$70 off
$104
per night
$230 total
includes taxes & fees
Tantalo Hotel
A modern hotel entrance with a prominent 'NOVOTEL' sign, large glass windows, and geometric light patterns on the facade.
A bar area with a variety of liquor bottles, a counter, and seating with tables and chairs.
A spacious lobby with large windows, a curved ceiling, and a seating area with a patterned rug.
A hotel room with a bed and a view of a cityscape through sheer curtains.

Novotel Panama City

Novotel Panama City
Bella Vista
$27 off
$123
per night
$271 total
includes taxes & fees
Novotel Panama City
A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.
A modern living room with a sofa set, a coffee table, and a dining area with chairs and a table.
A spacious lobby with a central seating area, a chandelier, and a modern ceiling design.
A hotel room with a bed, a TV, a desk, and a view of the cityscape through a window.

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
Bella Vista
$85 off
$138
per night
$151 total
includes taxes & fees
Hotel Riu Plaza Panama
A modern lobby with a chandelier, seating area, reception desk, and a staircase.
A dining area with a glass table, wicker chairs, a plate of fruit, and a cocktail glass.
A lobby with a reception desk, seating area, and a bar.
A hotel dining area with wicker chairs, a bar counter, and pendant lighting.

The Executive Hotel

The Executive Hotel
Bella Vista
$23 off
$90
per night
$98 total
includes taxes & fees
The Executive Hotel
A multi-story building with balconies, arched windows, and decorative railings.
A multi-level atrium with wooden staircases, seating areas, and a decorative ceiling.
A spacious lobby with a wooden staircase, multiple seating areas, and a reception desk.
A rooftop swimming pool with lounge chairs, potted plants, and a view of a city skyline including a prominent building with a dome.

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
Casco Viejo
$246 off
$213
per night
$235 total
includes taxes & fees
Central Hotel Panama Casco Viejo
A high-rise building with a modern architectural design, featuring a grid of windows and balconies.
A modern spa area with a hot tub, seating, and a city view.
An escalator in a hotel lobby with a patterned wall and framed artwork.
A rooftop lounge with modern seating and a panoramic city view.

Megapolis Hotel Panamá

Megapolis Hotel Panamá
San Francisco
$161
per night
$177 total
includes taxes & fees
Megapolis Hotel Panamá
A modern living room with a sofa, a coffee table, a flat-screen TV, and a view of greenery through large windows.
A swimming pool with a wooden bridge, surrounded by palm trees and lounge chairs.
A conference room with a long table, chairs, and a carpeted floor.
A playground with multiple slides and climbing structures.

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
Tocumen Airport
$108
per night
$119 total
includes taxes & fees
Riande Aeropuerto Hotel & Casino
A spacious outdoor patio with wicker furniture, potted plants, and umbrellas providing shade.
A dimly lit restaurant with wooden decor, tables, and chairs arranged for dining.
A hotel with a covered entrance, multiple windows, and a balcony with plants.
A modern hotel lobby with beige sofas, marble flooring, and a reception desk.

Hotel San Felipe

Hotel San Felipe
Casco Viejo
$153
per night
$168 total
includes taxes & fees
Hotel San Felipe
A rooftop pool with lounge chairs and a city skyline view.
A gym with treadmills, elliptical machines, free weights, and a bench.
A person seated on a wicker chair with a view of a cityscape through large windows.
A hotel room with a bed, a sofa, an ottoman, a wall-mounted lamp, and a wardrobe.

Hotel Dann Carlton Marinn Place Panama Financial District

Hotel Dann Carlton Marinn Place Panama Financial District
Bella Vista
$36 off
$82
per night
$118 total
includes taxes & fees
Hotel Dann Carlton Marinn Place Panama Financial District
A covered outdoor seating area with a view of a city skyline and water.
A nighttime view of a high-rise building complex with illuminated windows and a prominent red-lit structure.
A hotel room with two beds, a desk, and a large window offering a city view.
A cityscape with high-rise buildings, a waterfront, and a modern sculpture.

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
San Francisco
$119
per night
$131 total
includes taxes & fees
Plaza Paitilla Inn Hotel
A rooftop pool with sun loungers and a city skyline in the background.
A long, narrow hallway with a wooden floor and light-colored walls.
A modern hotel room with a large bed, a desk, a chair, and a wardrobe.
A bar area with a curved counter, multiple screens, and a patterned carpet.

Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
Bella Vista
$71
per night
$133 total
includes taxes & fees
Waymore Hotel Spa & Casino
A restaurant with multiple dining tables, chairs, and a central water feature.
A historic building with ornate stonework and a balcony with plants.
A bar area with multiple seating options, a bar counter, and a fireplace.
A modern living room with a sofa, a coffee table, and a TV mounted on the wall.

Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
Casco Viejo
$53 off
$299
per night
$329 total
includes taxes & fees
Hotel La Compañía Casco Antiguo
A rooftop bar with a city skyline view, outdoor seating, and a bar area with bottles and glasses.
A hotel room with a large bed, a painting on the wall, a door, and a small table with a lamp.
A modern living room with a purple wall, two abstract paintings, a white sofa with colorful cushions, a wooden coffee table with books and bottles, and patterned floor tiles.
A room with a kitchenette, a sofa, a bed, and a mural with the phrase "Just Breathe".

Tantalo Hotel

Tantalo Hotel
Casco Viejo
$25 off
$76
per night
$83 total
includes taxes & fees
Tantalo Hotel
A hotel named PRINCIPE with a modern facade and large glass windows.
A swimming pool with lounge chairs and a table.
A hotel lobby with a reception desk, seating area, and a visible sign for 'PRINCIPES HOTEL & SQUITES'.
A hotel reception area with a modern design, featuring a reception desk, white chairs, and a visible fire feature.

Principe Hotel and Suites

Principe Hotel and Suites
Bella Vista
$20 off
$59
per night
$65 total
includes taxes & fees
Principe Hotel and Suites
A spacious indoor area with high ceilings, large windows, and multiple dining tables.
A restaurant with brick walls, arched windows, and a variety of seating arrangements including tables and chairs.
A multi-story hotel with a central courtyard, balconies, and a view of the city skyline.
A spacious lobby with a tiled floor, large windows, and potted plants.

American Trade Hotel

American Trade Hotel
Casco Viejo
$217
per night
$238 total
includes taxes & fees
American Trade Hotel
A modern lobby with a glass railing, a central staircase, and a view of the cityscape through large windows.
A modern hotel room with a large window offering a city view, a chandelier, and a cozy seating area.
A modern living area with a sofa, chairs, and a coffee table. There is a view of the city through large windows.
A spacious lobby with a staircase, seating area, and a bar.

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
San Francisco
$167
per night
$184 total
includes taxes & fees
Las Americas Golden Tower Panama
A spacious indoor courtyard with tiled flooring, multiple seating areas, and hanging plants.
A four-poster bed with a black and white bedspread, two bedside tables with lamps, and a robe hanging on a rack.
A living room with a sofa, a coffee table with books, a chandelier, and a kitchen with wooden cabinets and granite countertops.
A room with a large window, a television mounted on the wall, and two chairs.

La Isabela Suites

La Isabela Suites
Casco Viejo
$18 off
$158
per night
$173 total
includes taxes & fees
La Isabela Suites

Check out pet-friendly hotels in Panama City

A modern living room with a sofa, a coffee table, a flat-screen TV, and a view of greenery through large windows.
A swimming pool with a wooden bridge, surrounded by palm trees and lounge chairs.
A conference room with a long table, chairs, and a carpeted floor.
A playground with multiple slides and climbing structures.

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
Tocumen Airport
$108
$119 total
includes taxes & fees
Oct 1 - Oct 2
Riande Aeropuerto Hotel & Casino
A spacious lobby with a high ceiling, modern lighting fixtures, and a glass entrance leading to a lower level.
A modern bar area with a central island, bar stools, and a television mounted on the ceiling.
A swimming pool with a clear water surface, surrounded by a covered area with lounge chairs and a bar area.
A modern restaurant with checkered flooring, wooden chairs, and large windows offering a view of greenery.

Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
Tocumen Airport
$130
$150 total
includes taxes & fees
Oct 30 - Oct 31
Crowne Plaza Panama Airport by IHG
A rooftop pool with a city view, lounge chairs, and a clear sky.
A modern lobby with a curved grey sofa, a round coffee table, and an orange armchair. There are potted plants and a reception desk in the background.
A modern lounge area with a bar, seating, and a large window offering a city view.
A modern kitchen with a marble countertop, a refrigerator, and a dining area with a table set for two.

Corporate Stays Arcadia | Executive Furnished Apartments

Corporate Stays Arcadia | Executive Furnished Apartments
Costa del Este
$104
$167 total
includes taxes & fees
Oct 3 - Oct 4
Corporate Stays Arcadia | Executive Furnished Apartments
A pool area with a covered patio, outdoor seating, and a bar area.
A building with a covered outdoor area, multiple windows, and a fire extinguisher mounted on the wall.
A modern hotel room with a dining area, a bed, and a large window.
A modern hotel room with a bed, a desk, and a wardrobe.

Albrook Inn

Albrook Inn
Panama City
$69
$76 total
includes taxes & fees
Sep 30 - Oct 1
Albrook Inn
A modern cafe with large windows, wooden tables, and chairs.
A modern living space with a grey sofa, yellow chairs, a kitchen area with a TV, and potted plants.
A modern kitchen with a central island, a built-in microwave, and a dark-colored sofa in a living area.
A modern kitchen with grey cabinets, a stainless steel sink, and a built-in microwave. There is a red door in the background and a painting on the wall.

Nomada Container Hotel Panama City

Nomada Container Hotel Panama City
Bella Vista
$66
$80 total
includes taxes & fees
Sep 30 - Oct 1
Nomada Container Hotel Panama City
A conference room with a large table, chairs, a potted plant, and a curtain backdrop.
A buffet setup with various dishes and a decorative plant.
A dining area with a round table, chairs, and a view of a swimming pool and palm trees.
An outdoor dining area with tables and umbrellas, a person playing a saxophone, and a building with illuminated windows in the background.

Riande Urban Hotel

Riande Urban Hotel
Bella Vista
$91
$100 total
includes taxes & fees
Sep 30 - Oct 1
Riande Urban Hotel
Pool
A balcony with a view of a swimming pool, palm trees, and city buildings.
A hotel room with a large bed, a smaller bed, a sofa, a TV mounted on the wall, and a dining area with a table and chairs.
A buffet area with a variety of dishes, a long counter with food, and a seating area with tables and chairs.

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Bella Vista
$100
$110 total
includes taxes & fees
Oct 27 - Oct 28
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
An outdoor patio area with wicker furniture and glass-top tables, surrounded by lush greenery and a view of the interior.
A rectangular swimming pool with a tiled edge, surrounded by a tiled patio area.
A garden with a concrete pathway, various plants, and a birdcage.
A hotel room with a bed, a ceiling fan, a TV, a refrigerator, and a window with curtains.

The Balboa Inn

The Balboa Inn
Balboa
$74
$81 total
includes taxes & fees
Sep 30 - Oct 1
The Balboa Inn
A swimming pool with a water feature, surrounded by plants and seating areas.
A bar area with a long counter, multiple bar stools, and a television screen displaying a sports event.
A modern reception area with a teal accent wall, a reception desk, two white chairs, and a computer monitor.
A hotel courtyard with a swimming pool, outdoor seating, and a building with multiple balconies.

Holiday Inn Panama Canal by IHG

Holiday Inn Panama Canal by IHG
Panama City
$98
$119 total
includes taxes & fees
Oct 5 - Oct 6
Holiday Inn Panama Canal by IHG
A restaurant with booths, a neon-lit red wall, hanging plants, and pendant lights.
A hotel room with a bed, a sofa, a coffee table, a desk, and a large window with a city view.
Rooftop pool
A hotel room with a large bed, a desk, a chair, a sofa, and a view of the cityscape.

Hotel Mio Panama

Hotel Mio Panama
Bella Vista
$58
$64 total
includes taxes & fees
Sep 30 - Oct 1
Hotel Mio Panama
View all properties

You may also like hotels with pools in Panama City

A modern living room with a sofa, a coffee table, a flat-screen TV, and a view of greenery through large windows.
A swimming pool with a wooden bridge, surrounded by palm trees and lounge chairs.
A conference room with a long table, chairs, and a carpeted floor.
A playground with multiple slides and climbing structures.

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
Tocumen Airport
$108
$119 total
includes taxes & fees
Oct 1 - Oct 2
Riande Aeropuerto Hotel & Casino
A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.
A modern living room with a sofa set, a coffee table, and a dining area with chairs and a table.
A spacious lobby with a central seating area, a chandelier, and a modern ceiling design.
A hotel room with a bed, a TV, a desk, and a view of the cityscape through a window.

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
Bella Vista
$138
$151 total
includes taxes & fees
Oct 25 - Oct 26
Hotel Riu Plaza Panama
A covered outdoor seating area with a view of a city skyline and water.
A nighttime view of a high-rise building complex with illuminated windows and a prominent red-lit structure.
A hotel room with two beds, a desk, and a large window offering a city view.
A cityscape with high-rise buildings, a waterfront, and a modern sculpture.

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
San Francisco
$108
$108 total
includes taxes & fees
Oct 12 - Oct 13
Plaza Paitilla Inn Hotel
A modern lobby with a chandelier, seating area, reception desk, and a staircase.
A dining area with a glass table, wicker chairs, a plate of fruit, and a cocktail glass.
A lobby with a reception desk, seating area, and a bar.
A hotel dining area with wicker chairs, a bar counter, and pendant lighting.

The Executive Hotel

The Executive Hotel
Bella Vista
$89
$98 total
includes taxes & fees
Oct 21 - Oct 22
The Executive Hotel
A hotel named PRINCIPE with a modern facade and large glass windows.
A swimming pool with lounge chairs and a table.
A hotel lobby with a reception desk, seating area, and a visible sign for 'PRINCIPES HOTEL & SQUITES'.
A hotel reception area with a modern design, featuring a reception desk, white chairs, and a visible fire feature.

Principe Hotel and Suites

Principe Hotel and Suites
Bella Vista
$59
$65 total
includes taxes & fees
Sep 30 - Oct 1
Principe Hotel and Suites
A rooftop pool with sun loungers and a city skyline in the background.
A long, narrow hallway with a wooden floor and light-colored walls.
A modern hotel room with a large bed, a desk, a chair, and a wardrobe.
A bar area with a curved counter, multiple screens, and a patterned carpet.

Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
Bella Vista
$71
$133 total
includes taxes & fees
Sep 30 - Oct 1
Waymore Hotel Spa & Casino
A high-rise building with a modern architectural design, featuring a grid of windows and balconies.
A modern spa area with a hot tub, seating, and a city view.
An escalator in a hotel lobby with a patterned wall and framed artwork.
A rooftop lounge with modern seating and a panoramic city view.

Megapolis Hotel Panamá

Megapolis Hotel Panamá
San Francisco
$161
$177 total
includes taxes & fees
Sep 30 - Oct 1
Megapolis Hotel Panamá
A hotel room with two single beds, a small table with a chair, a TV mounted on the wall, and a marble-patterned headboard.
A rectangular swimming pool with blue tiles and a brick border.
A modern interior with a staircase, a seating area with a bench and tables, and a counter with a sign reading "NISATO".
A two-story building with a sign reading "HOTEL EXPRESS INN".

Express Inn Panama International Airport Hostel

Express Inn Panama International Airport Hostel
Tocumen Airport
$50
$54 total
includes taxes & fees
Sep 30 - Oct 1
Express Inn Panama International Airport Hostel
A spacious lobby with a high ceiling, modern lighting fixtures, and a glass entrance leading to a lower level.
A modern bar area with a central island, bar stools, and a television mounted on the ceiling.
A swimming pool with a clear water surface, surrounded by a covered area with lounge chairs and a bar area.
A modern restaurant with checkered flooring, wooden chairs, and large windows offering a view of greenery.

Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
Tocumen Airport
$130
$150 total
includes taxes & fees
Oct 30 - Oct 31
Crowne Plaza Panama Airport by IHG
A modern, well-lit buffet area with a variety of food items and neatly arranged plates.
A spacious indoor area with a high ceiling, potted plants, and a seating arrangement.
An outdoor swimming pool with lounge chairs and umbrellas, surrounded by potted plants.
A modern living room with a sofa, armchairs, a coffee table, and a dining area with a table and chairs.

Best Western El Dorado Panama Hotel

Best Western El Dorado Panama Hotel
Bethania
$100
$110 total
includes taxes & fees
Oct 9 - Oct 10
Best Western El Dorado Panama Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Our prices for hotels in Panama City are cheapest in April
Price trends for hotels in Panama City
Pricing is based on two traveler single night rates
View properties in September
Typical weather for Panama City
September
High 29°C / low 24°C. Rainy most days.
View properties in September
29°
24°
29°
24°
29°
24°
29°
24°
30°
24°
30°
24°
31°
24°
31°
24°
30°
25°
29°
25°
29°
24°
29°
24°
Monthly weather averages (˚C)

Top neighborhoods in Panama City

A coastal cityscape with a prominent church tower, a river, and distant mountains.
A statue of a man on horseback, a white building with balconies, and a well-lit plaza.
A cityscape with historic buildings, a statue, and a clear sky.
A historic building with ornate balconies and a clock tower in the background.
A statue with inscriptions, a flag, and a church with a bell tower.
Photo by Botak Jon

Casco Viejo

Casco Viejo's cobblestone streets tell Panama's colonial story at every turn. The golden Metropolitan Cathedral and historic theaters create a living museum vibe. Rooftop bars offer spectacular bay views while museums showcase Panama's diverse heritage. Plaza hopping rewards you with hidden architectural gems and cultural performances that bring history to life. The neighborhood serves up everything from fusion cuisine in restored mansions to traditional Panamanian dishes. Boutique hotels occupy colonial buildings with charming courtyards and personalized service. Though compact, comfortable walking shoes are essential for navigating the uneven historic streets.

A harbor with several boats docked in the foreground and a city skyline in the background.
Photo by Journey Of A Nomadic Family
A modern, spiraling skyscraper with a unique design, surrounded by other buildings in an urban setting.
Photo by Fabiola Tile
A coastal cityscape with high-rise buildings and a curved bay.
Photo by Freddy Dominguez
A cityscape with modern skyscrapers, including a distinctive twisting tower.
Photo by Fabiola Tile
A city street lined with palm trees and high-rise buildings.
Photo by Vladimirs Pirtins

Bella Vista

Bella Vista balances Panama City's sleek business side with upscale urban living. Gleaming skyscrapers along Avenida Balboa house financial headquarters while trendy spots on Calle Uruguay buzz with after-work crowds. Shop at MultiPlaza Pacific mall, visit Crown Casino, or simply stroll the waterfront promenade for stunning bay views. Getting around is a breeze with two metro stations and plentiful taxis. Dining options range from rooftop restaurants to international cuisine that won't disappoint. High-rise hotels with spectacular views cater to business travelers and tourists who appreciate modern comforts with a side of ocean breeze.

A city skyline with modern high-rise buildings and a river in the foreground.

El Cangrejo

El Cangrejo pulses with modern energy around the iconic "El Tornillo" tower, where art meets business in Panama City's cosmopolitan heart. Korean BBQ aromas mingle with coffee scents from sidewalk cafes, while galleries showcase local talent beneath tropical sunshine. Colorful murals splash across office buildings as diverse cultures blend in this trendy district. The neighborhood serves up an eclectic fusion of Korean, Jewish, and Panamanian cuisines in stylish eateries and casual cafes. Modern boutique hotels and upscale business lodging dominate accommodation options. Getting around is a breeze with nearby Metro Line 1 stations, abundant taxis, and pleasantly walkable streets.

A modern, spiraling skyscraper with a unique design, surrounded by other buildings in an urban setting.
Photo by Fabiola Tile
A harbor with several boats docked in the foreground and a city skyline in the background.
Photo by Journey Of A Nomadic Family
A cityscape with modern high-rise buildings and a clear blue sky.
A cityscape with modern skyscrapers, including a distinctive twisting tower.
Photo by Fabiola Tile
A spiraling skyscraper against a clear blue sky.
Photo by My World

Obarrio

Obarrio dazzles with gleaming skyscrapers housing Panama City's financial powerhouses and luxury shopping. Multiplaza Pacific mall tempts with designer boutiques while the business crowd buzzes between meetings. When you're not trying your luck at local casinos, relax at a sophisticated coffeehouse or stroll the wide, clean sidewalks of Calle 50. Hotels range from international chains to boutique properties, with rates reflecting the upscale surroundings. Getting around is a breeze with excellent taxi service, frequent buses along Via España, and the Metro Line 1 connecting directly to Iglesia del Carmen station.

A coastal cityscape with high-rise buildings and a marina.
A city skyline with tall buildings and a clear blue sky.

Punta Pacifica

Punta Pacifica's gleaming glass towers and an iconic sail-shaped skyscraper create a skyline that screams luxury with a Pacific Ocean backdrop. Stroll the waterfront promenades where swaying palms frame perfect sunset views, or duck into Multiplaza Pacific Mall to browse designer boutiques in marble-floored splendor. The neighborhood balances business and pleasure with its mix of corporate offices and upscale leisure spots. Dining here means international cuisine with ocean views at rooftop bars and hotel restaurants where reservations are smart moves. High-rise hotels and serviced apartments offer amenities like infinity pools and concierge services. Getting around is easy with abundant taxis and walkable streets, though you won't find much public transit in this polished enclave.

Top landmarks in Panama City

A cityscape with a rainbow over buildings.
Photo by Fabiola Tile

Multiplaza Pacific Mall

9.0/10 (4,497 reviews)
If you want to give your credit card some exercise, head out to Multiplaza Pacific Mall in San Francisco. Splash some more cash at Avenida Balboa, Multicentro Panama, and Pacific Center.
See properties
A marina with numerous boats, a bridge in the background, and lush green hills.

Amador Causeway

9.0/10 (1,902 reviews)
If you're planning a bit of sightseeing head to Amador Causeway— just one of the monuments in Amador. You can also discover the churches and cathedral in the area— your sightseeing tour starts here. It's also full of great shops and restaurants, so you can spend the afternoon having a wander.
See properties
A city skyline with tall buildings along a waterfront.
Photo by Rob Gosse

Cinta Costera

9.2/10 (3,823 reviews)
Cinta Costera is worth a pic or two when discovering Calidonia.
See properties
A nighttime cityscape with illuminated skyscrapers and a river reflecting the lights.

Avenida Balboa

8.8/10 (3,608 reviews)
If you want to give your credit card some exercise, head out to Avenida Balboa in Calidonia. Splash some more cash at Multicentro Panama, Uruguay Street, and Multiplaza Pacific Mall.
See properties

Albrook Shopping Mall

8.6/10 (4,561 reviews)
Don't visit Ancon without stopping off at Albrook Shopping Mall, a top spot for shopaholics. It's also full of great shops and restaurants, so you can spend the afternoon having a wander.
See properties

Via Espana

8.4/10 (2,902 reviews)
If you want to give your credit card some exercise, head out to Via Espana in Bella Vista. It's also full of great shops and restaurants, so you can spend the afternoon having a wander. Splash some more cash at Uruguay Street, Multicentro Panama, and Avenida Balboa.
See properties

Fuerte Amador Resort & Marina

9.4/10 (169 reviews)
You can stroll along Fuerte Amador Resort & Marina for relaxing water views when you're in Amador. It's also full of great shops and restaurants, so you can spend the afternoon having a wander. If you carry on walking you'll get to Panama Cruise Terminal for some more water views.
See properties

El Dorado Mall

8.2/10 (1,337 reviews)
If you want to give your credit card some exercise, head out to El Dorado Mall in Bethania. It's also full of great shops and restaurants, so you can spend the afternoon having a wander.
See properties

Learn more about Panama City

Wander through the historic Casco Viejo district, marveling at colorful colonial buildings and bustling plazas. Cruise through the famous Panama Canal, watching massive ships navigate the ingenious locks system.

See all hotels in Panama City
A city skyline with high-rise buildings, a calm waterfront, and a sunset sky.

Check out reviews of Panama City hotels guests love

Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

10/10 Excellent
"The room was so clean, the staff was so help full. The hotel is next to the Múlti Plaza so well located."
Dailexy 1-night trip
Posted 1 hour ago
Courtyard by Marriott Panama Multiplaza Mall
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"My husband and I were impressed by the attentiveness of the staff. We had an issue with our first room and they quickly moved us to another room. They also called to check on us and sent a fruit plate and apology note. Overall a great experience."
Martin Anthony 3-night trip
Posted 4 hours ago
Hotel Riu Plaza Panama
Principe Hotel and Suites

Principe Hotel and Suites

8/10 Good
"Si incluyen desayuno sería mejor"
Ruben 4-night trip
Posted 5 hours ago
Principe Hotel and Suites
Hyatt Regency Panama City

Hyatt Regency Panama City

10/10 Excellent
"All staff were professional, capable and helpful. The front desk staff, particularly Isaac, stand out for their efforts to assist. I received expert recommendations and directions as well as hospitality at a five star level."
Jeffrey C 9-night trip
Posted 6 hours ago
Hyatt Regency Panama City
Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

10/10 Excellent
"Excelente ubicación, cerca de un centro comercial importante y de restaurantes. Las habitaciones geniales. Para el precio que se paga la calidad que se obtiene es buenísima. Totalmente recomendable"
Hector 3-night trip
Posted 7 hours ago
Ramada Plaza by Wyndham Panama Punta Pacifica
Megapolis Hotel Panamá

Megapolis Hotel Panamá

10/10 Excellent
"Execelente servicio solo como sugerencia! Se necesita un microondas en la habitación on en algún pasillo que pueda estar disponible por pasillo ya que aveces ay alimentos que se necesitan calentar 2 un mini market que pueda estar abierto las 24 horas dentro del hotel eso beneficiaría tanto al hotel como al huésped! De lo contrario todo Execelente las habitaciónes y donde se toma el desayuno es de lo mejor , muy recomendable…"
Jaime Alexander 3-night trip
Posted 7 hours ago
Megapolis Hotel Panamá
Aloft by Marriott Panama

Aloft by Marriott Panama

10/10 Excellent
"The bar and the cleanliness of the room were great. Breakfast selection options was also good."
Erick 3-night trip
Posted 7 hours ago
Aloft by Marriott Panama
Hospedium Princess Hotel Panama

Hospedium Princess Hotel Panama

10/10 Excellent
"We had a nice clean room, the breakfast buffet was very good and switched up every morning, the pool and pool bar was a great place to hang out at, and the staff was truly amazing"
Robert Hawk 5-night trip
Posted 23 hours ago
Hospedium Princess Hotel Panama
The Executive Hotel

The Executive Hotel

10/10 Excellent
"Great great Staff and I thought the morning buffet was pretty good! Only issue is WiFi going on and off. Works well on the bottom floor but 7th floor it was very shaky. Overall AMAZING experience. Great location aswell. Thanks so much to the beyond awesome staff!"
Desta 6-night trip
Posted 1 day ago
The Executive Hotel

Frequently asked questions

What accommodations do travelers like in Panama City?
Guests like Hotel Riu Plaza Panama, Central Hotel Panama Casco Viejo and Megapolis Hotel Panamá.
Where can I find free parking with my stay in Panama City?
Park your car for free at these properties: Marriott Panama Hotel, Canova and Gran Evenia Panama. You can browse all 20 options on our site.
Can I book a refundable accommodation in Panama City?
If you need the flexibility to change your plans to Panama City, most hotels provide refundable* rates you can book. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
Where should I consider staying in Panama City if I want an affordable accommodation?
Hotel Faranda Express Soloy and Casino, a member of Radisson Individuals is an accommodation you might want to consider that'll save you money. You may want to browse all 36 choices on our site.
Where can I stay in Panama City if I want a vacation home instead of a traditional hotel?
If you want a good alternative to a hotel, browse our selection of 59 vacation homes. In addition, there are 1107 apartments and 144 condos.
What will the weather in Panama City be like during my visit?
With an average temperature of 79°F during the coldest months, Panama City is a great place to visit any time of year.
Why should I book my Panama City hotel with Hotels.com?
There are plenty of reasons to book your Panama City travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.